Cimicifuga

Cimicifuga racemosa, Ell. Synonyms, Actsea racemosa, Linn ; Macrotys actseoides, Rat. ; Botroflus serpentaria, Rat. (Med. Flora).

Nat. order, Ranunculacese. Common names, Blacksnake root, Bugbane, Rattleweed.

Preparation, Tincture of the root.

Authorities. 1, Dr. T. S. Garden, effects of " full doses," Araer. Med. Recorder, 1823 (from Wibmer); 2, G. W. Mears, took an ounce of "saturated tincture" in two hours, in divided doses, Hempel's Mat. Med., 2, 506; 3, Chas. H. Burr, proving with fluid extract, 10 drops hourly for fourteen hours, then after twenty-four hours, 15 drops hourly for twelve hours, Inaug. Thesis, Horn. Med. Coll. of Penn., 1858 (from Hempel's Mat. Med., 2, 507) ;f 4, Dr. H. M. Paine's provings, repeated doses of the tincture, 10 to 40 drops (five different provings), N. Am. J. of Horn., 3, 207 ; 5, ibid., proving with the 6th dec. dil.; 6, Mr. S., proving with tincture, 5 to 20 drops, ibid.; 7, Mrs. A., proving with daily repeated doses of tincture, 10 to 20 drops, ibid.; 8, Dr. L. B. Wells, proving with 1st dil. (first day 3 drops, third day 3 drops), ibid.; 9, Dr. Luther Wells, proving with tincture, 102 drops in seven days, afterward 178 drops in eight days, afterward 210 drops in seven days; 10, resume of provings of Drs. Hill and Douglass, N. Am. J. of Horn., 7, 450, "provings on forty men and six women, medical students, entirely ignorant of what they were taking ;"J 11, Dr. Bacmeister's provings with half a teaspoonful of the tincture, Trans. Am. Inst. Horn., 1871 ; 12, Mrs. L. B., ibid.; 13, two girls took repeated doses of the 12th dil., ibid.; 14, Mrs. L. B. took half a teaspoonful of tincture, ibid.; 15, Mr. W. took 10 drops of tincture every four hours, Trans. Am. Inst, of Horn., 1872 ; 16, Cooper, effects of 1st dec. taken ten days, in a woman of 35, who had not menstruated for fifteen years, M. H. R., 15, 179 ; 17, Garrison, poisoning of a pregnant woman by 1 drachm of Squibb's fl. ext., Br. and F. Med.-Chir. Rev., 1869; 18, Chapman, effects, Elem. of Therap., 1, 357 (1831) ; 19, Davis, effects of large doses, Trans. Am. Med. Assoc., 1, 352 ; 20, Young, effects of a teaspoonful three times a day for chorea, Am. J. of Med. Sc., 9, 313.

Mind

Emotional. A sort of delirium, with an inclination to run over the subject on which he was reading

Half intoxicated feeling, with swimming of the head (after half an hour)

* Miserable, dejected feeling

In afternoon, depression and dulness (second day)

Anxiety

* Feels grieved and troubled, with sighing ; next day, a feeling of tremulous joy, with mirthfulness, playfulness, and clear intellect,10.-^ Intellectual. Mind clear (as a first effect)

Mind dull and heavy

Not disposed to fix the attention

* Not disposed to fix the attention on any subject (second day),6. J J y

Head p. 297

Vertigo. Vertigo

Vertigo to such an extent that she could not sit up (after two hours)

* Vertigo, fulness and dull aching in vertex (after ten minutes)

* Vertigo, impaired vision, dizziness, dulness, with fulness and aching in the vertex

Dizziness, dulness in the head (second day)

General Head. Dulness and heaviness of the head and eyelids, as if produced by cold

Dulness of the head, and pain in forehead and occiput (fourth day)

* Dull sensation throughout the head, as though he had been on a spree and was getting over the effects

Heaviness in head

Heaviness and dulness of the head

Heaviness, dulness, fulness, slight dull pain

Pains in head and face constant, and very severe

Slight pain in the head/.

Slight pain in the head, in the evening

* Great pain in the head, back, and limbs (after two hours)

Severe pains in the head, with much somnolency and coldness (after one hour), followed by warmth (after two hours)

On waking, had a most distressing pain in the head, with vertigo, flushed face, dilated pupils, and an increase of twelve beats in the frequency of the pulse (after three hours)

Slight dull pain in head

* Constant dvM pain in the head, particularly in the occiput, extending to the vertex, during the forenoon and part of the afternoon (second day)

Fulness and pressure in the brain (second day)

Slight fulness of head

Feeling of fulness, with headache

Sense of fulness and heaviness of the head ; soon after dull pain of forehead, heat of face, and slight sweat

Head feels too large

Brain felt too large for cranium ; brain feels compressed

Headache

Dull headache on getting up in morning

Dull, heavy headache, more in left temple, at 9 a.m. (second day)

* Aching pain in head, particularly in occiput, experienced only while indoors, relieved by the open air ; it increased during the afternoon, and was quite severe in the evening ; avoid 9 p.m. it disappeared entirely, after a walk in the open air (after two hours)

Feeling of pressure in head, and heat in head and face (after one hour)

Head and eyes relieved from an existing pressure

Acute pain generally through the head, during the day, at times more severe on the left side

* The pain in the head is always relieved by the open air

Forehead. Pain in front and top of head

Pain in forehead, which seemed to proceed from the right temple in burning lines, accompanied after an hour by a sense of fulness and heat; pain, heat, and fulness soon become continuous, with a sense of drowsiness (10- drop doses)

Pain in forehead and occiput, with heaviness of head (after one hour); the pain in the head continued for ten days

Slight pain in forehead, with dryness of the pharynx, and aching in the eyes, apparently between the eyeball and orbital plate of the frontal bone, at 10 p.m. (fourth day)

Occasional transient pain in forehead over right eye

Dull pain in forehead, in afternoon

Dull pain in forehead, before breakfast (second day)

Dull pain deep in forehead (soon after)

Dull boring pain in forehead over left superciliary ridge, continuing for two hours (after three hours)

Awoke at 2 A.m., with excruciating though dull pain in forehead, extending to temples, with coldness of forehead

Headache (frontal), (fourth day)

After hearty dinner, headache in left frontal region, continuing at intervals during the rest of the day ; worse outdoors ; after sleep, headache as before, worse during a walk out of doors ; better after entering a room (second day)

Pressure in front part of head and eyes

Temples. Pain in left temple

Headache through the temples ; headache as if it would burst

Sensation as if the temples were compressed, occasionally through the day

Sharp cutting pain in right temples (immediately)

Vertex. *Pain in vertex, during afternoon and evening

Fulness in vertex, in evening

Full feeling in upper part of brain, with dull feeling

* Aching pains in vertex and occiput, in paroxysms at times quite severe, immediately after rising ; the pains continued through the day, but not so severe as in the morning (second day)

After one hour, aching pain and soreness of vertex, increasing to great severity; after two or three hours passing to the frontal part of the head, continuing all night, and depriving him of sleep

* Pain from the eyes to the top of the head; it seemed as if the nerves were excited to too much action, lasting three hours ; under larger doses it lasted six hours

* DuU pain in the region of the moral organs ; a pressing outward and upward, as if there was not room enough in the upper portion of the cerebrum ; this pain was very oppressive and almost intolerable ; it began about 5 oclock p.m., after taking the second dose, and continued unabated till morning, when it was relieved in thirty minutes by a single dose of Bryonia

Patietals. Slight pain in left side of head (soon after)

Fulness on left side

Dull pressive pain in left side of head

Occiput. Pain extending from the right eyeball through to right side of occiput, slightly affecting the ear, at night

* The pain in the head seemed to extend, over and through the whole brain, producing a distinct sense of soreness in the occipital region, which was much increased by motion (15-drop doses)

Eyes p. 298

* During the headache the eyes were so congested as to attract the attention of every one, although there was no disagreeable feeling in them

Heaviness of the eyes, as if caused by cold

Eyes feel as if swollen

Aching of the eyes at 10 a.m. (fourth day)

Dull aching pain in eyes (fourth day)

IZroiV. Pain over the eyes (second day)

Pain over left eye, extending along the base of the brain to the occiput (second day)

Severe pain just over right eye

Acute pain over left eye ; in forehead, occiput, vertex, etc., in paroxysms ; pain relieved by the open air

Shooting pain over left eye (fourth day)

Lids. Inflammation of both eyelids (second day)

During afternoon, pain in right eyelid when closing it

Sensation of swelling of right eyelid, with heat, as if inflamed (after four hours)

Stinging in the eyelids (after one hour)

Stinging and inflammation of the lids

Hall. *Pain in the eyeballs

* Pain in both eyeballs (fifth day)

* Pain in the centre of the eyeballs, and also sensation as if pain were situated between the eyeball and the orbital plate of the parietal bone, in the morning on rising, continuing all day, but not so severe as in the morning (second day)

Eyeballs occasionally painful for a short time

Eyeballs painful for a short time in the forenoon (second day)

Pain in the eyeballs continued for two weeks after discontinuing the drug

Dull pain in both eyeballs

* Aching pain in both eyeballs, through the day (fourth day)

Severe aching pain in right eyeball, after retiring for the night

Constant dull aching pain in right eyeball and across forehead, accompanied with nausea

Pupils, Dilated pupils

Pupils dilated (after three hours)

Pupils enormously dilated (after two hours)

Vision. Vision very much disordered (after two hours)

Dimness of vision

Myopia increased

* Black specks before eyes

Nose p. 298

Objective, Sneezing

Sneezing at 4 p.m. (fourth day)

coryza during the day (second day) 4._Obstruction of left nostril, in even-

Face p. 299

After pain in the head, which continued ten days, coryza, sore throat, and extension to bronchial mucous membranes

the pain in the head was followed by coryza, with sore throat and a gradual extension of the disease to the bronchial mucous membrane, dry, short, and hacking cough night and day, continuing two weeks, which is uncommon, the prover not having had a catarrh or cold for several years,8.-Constant coryza during i 5iy -

martius and burning coryza relieved

Fluent coryza (third day )

blueut coryza of whitish mucus, during the day

Fluent coryza aching, and soreness in the nose, during the day (second day)

Fluent coryza, more so than for many weeks, as if caused by cold, at 4 p.m. (fourth ?7 V nfc n -Vatei'y C0,Tza

Copious coryza (fourth day),4; (fifth day)

[L4U.J Copious coryza during the forenoon (fifth day)/.

Profuse coryza in the forenoon ; aching pain in the head ; pain in both eyeballs many times through the day (third day)

Very profuse, greenish, and slightly sanguineous coryza

Very profuse, greenish, and slightly sanguineous coryza, after rising (fourth day)

At first, dry, stuffed condition of the nostrils, which was soon followed by an open, moist condition, with great sensitiveness to the cold air, as if the base of the brain were laid bare, and eyer inhalation brought the cold air in contact with it ; this is exactly similar to that produced by a sudden change of weather in winter, from cold and drvto damp thawing, as by a south wind, which melts the snow

Subjective. Inclination to sneeze, twice in the afternoon

Frequent inclination to sneeze, in the afternoon

Fine stitch to outside of right wing of nose

Stinging sensation in the nose, in the evening (second day)

Face p. 299

Face flushed (after three hours)

Redness of face and eyes

Very severe pain in face, more in under jaw, lower teeth, and articulation of lower jaw

Cheeks. Pain in right superior maxillary bone and teeth

At 10 a.m., feeling of lateral expansion and pressure outward in both malar bones and forehead

Lips. Dry lips (second day)

Dry sore lips

Dryness and soreness of the lips

Jaws. Severe pain in left jaw,10. 1

Mouth p. 299

Teeth. Thick mucus on teeth

Accumulation of thick mucus upon the teeth (second day)

During afternoon, peculiar uneasiness in teeth ; wants to chew or pick at them

ToiH/ue. Swelling of back part of tongue

Roots of tongue and fauces swollen

Mouth in General. Mouth dry in morning

Dryness of lips and mouth

Palate and uvula red and inflamed

Saliva. Increased flow of saliva immediately

Spitting of thick saliva, which seemed to stick to the mouth and throat, and to be detached with difficulty

Taste. Unpleasant taste

Unpleasant taste in mouth (15-drop doses),3; (second day)4

Throat p. 299

{150.] Throat dry

D dryness and soreness of throat on swallowing and on pressure, worse on left side

Fulness of throat and vertex, and stiffness of neck

Sensation as if the throat was partly filled, as low as the top of the sternum

* Throat sore

Sore throat, when swallowing

Soreness of throat when swallowing; sensation of fulness high up in throat, with fulness in vertex and stiffness of neck, in evening

Sensation of rawness in throat

Sensation of rawness in throat; slight difficulty in swallowing; hoarseness, which increased towards night; constant unpleasant fulness in pharynx

Irritation of throat with expectoration of mucus for half an hour, resulting in the cure of an existing cold

Roughness and dryness of the throat, with thirst

Uvula. Inflammation of the uvula and palate, more severe than the day before (fifth day)

Fauces, Pharynx, and (Esophagus. Increased secretion of thick viscid mucus in the fauces

Dry pharynx

Dryness of the pharynx, and inclination to swallow, during the night (fourth day)

Dryness of the pharynx at 4 p.m. (fourth day)

Fulness of pharynx, and inclination to swallow

Fulness of the pharynx, and constant inclination to swallow (fourth day)

Constriction of the pharynx, with increased secretion of mucus in the throat

During forenoon, sense of empty aching all along oesophagus (second day)

Stomach p. 300

Appetite. Loss of appetite (second day) ; experienced during the last few days of the proving, and continued for two weeks after

No appetite for supper ; repugnance to food (second day)

Desire for tobacco decidedly weakened (second day)

Thirst. Thirst, but no desire to drink

Eructations. Eructations tasting of the medicine (immediately)

Eructations and slight nausea (immediately)

Eructations, nausea, and loss of appetite

Violent eructations, but no relief',10.

Nausea and Vomiting. Nausea

Nausea for fifteen minutes (after half an hour)

Nausea with loathing (soon after)

* Nausea and vomiting (during the first twelve hours)

* Nausea and vomiting

Nausea, vomiting, and much gastric irritation in females, while in males it was hardly noticed as affecting the stomach in the least

Nausea all through the abdomen, followed by a loose stool, accompanied by sharp pain in abdomen and considerable downward pressure in rectum (after two hours)

Some nausea, followed by greater freedom of expectoration and more or less relaxation of the surface, with slight nervous tremors and vertiginous affections

Slight nausea and burning of the stomach

Slight nausea, with weak, trembling, exhausted feeling

Slight nausea, which increased with a sickening pain in the duodenum ; half an hour afterwards, flatulence, eructations, and more nausea ; a second dose increased the symptoms, with general feeling of illness ; supper abated the bad feeling, but nausea returned soon after

Awful nausea, with tremors all over

Violent retching

Stomach. Distension of stomach and upper part of abdomen

* Faintness of the stomach?.

Faintness of the stomach, two or three times, of short duration

* Faintness and emptiness of stomach

Faintness in the epigastrium, with repugnance to food, which, however, did not prevent his partaking of a moderate breakfast (second day)

Faintness in the epigastrium, generally in the morning, before eating (particularly if the medicine had been taken over night), not preventing eating, which was followed by a sensation of repletion, as if too much food had been taken

Slight faintness in the epigastrium during the forenoon (second day)

Great uneasiness at the stomach (after three hours)

Pain and heat in the stomach followed by eructation, which afforded relief

Pain and heat in stomach, followed by eructations, which afforded relief; the sense of heat in stomach continued, with a feeling of warmth and dryness in the whole alimentary canal

Before breakfast, slight pain in the epigastrium, extending to the left hypochondrium, with faintness and sensation of emptiness (second day)

Feeling as if too much food had been taken

During afternoon, sensation as if too much food had been taken into the stomach

Acute darting pain in the epigastrium, after a light supper

Tremor in the stomach

Sense of internal tremor in the stomach, after breakfast (second day)

Abdomen p. 301

Hypochondria. Pain in left hypochondriac region, worse on motion and on taking a deep inspiration

Dull pain in region of liver

Umbilical. Rumbling of flatus below the umbilicus at 10 p.m. (fourth day)

Dull griping-twisting at the umbilical region, more towards the left,™.

Acute cutting pain at the umbilicus

Acute cutting pain in the umbilical region, which, although acute, was not so severe as to prevent attending to his usual business ; uninfluenced by eating, and continuing through the afternoon (after three hours)

General Abdomen. Flatus

Flatulence

Flatulence, causing a sensation of fulness in the abdomen, at 10 p.m. (fourth day)

Pain in the abdomen

Wandering pains in bowels

Dull, heavy pains in the abdomen

Fulness, pressure in abdomen

Griping pains in bowels, from the umbilicus down

Periodic colic, with inclination to bend forward, relieved after stool

Soreness of abdominal muscles on taking a full inspiration

Hypogastrium and Iliac Regions. Flatus; rumbling in lower part of abdomen at 10 a.m. (fourth day)

Rumbling in lower abdomen

Fulness and pressure in lower part of abdomen ; increased pressure next day, with some pain

Soreness in lower abdomen (second day)

Slight pain in left iliac region ; afterwards, severe pains in bowels, mostly below the umbilicus, with weight and pain in lumbar and sacral regions

Rectum and Anus p. 301

Disposition to diarrhoea

Disposition to diarrhoea, in the evening

Slight disposition to diarrhoea

Slight disposition to diarrhoea, after rising (second day)

Urging to stool ; inclined to diarrhoea

Stool p. 301

Diarrhoea. Scanty diarrhoea, with tenesmus (fourth dose)

Two copious papescent stools in morning

Copious papescent stool in morning

Large papescent stool, with general indisposition (after second dose)

Constipation. Faeces hard and dry

Constipation

Evacuations natural during provings, but alternate constipation and tendency to diarrhoea for a month after

Evacuation regular and natural during the proving, but for a month afterwards, alternate constipation and tendency to diarrhoea

Urinary Organs p. 301

Urethra. Violent stitches in urethra in morning

Disposition to frequent urination (second day)

Disposition to frequent urination, with increased secretion

Micturition. Increased secretion of pale urine

Increased flow of urine (second day)

Profuse flow of clear watery urine

Passes a great quantity of clear urine, which makes her feel very Aveak

During the first of the proving it was necessary to void urine about once an hour

Urine scanty and high-colored (fourth day)

Retention of urine for eighteen hours, followed by frequent micturition

Urine. The second specimen showed that from a normal standard the urine in sp. gr. had gone down to 1.005. The following specimen showed that a change was taking place, and the next that it had gone up to 1.019. It soon reached 1.020, at which point it remained. It was collected in a vessel, and allowed to repose till the expiration of twenty-four hours, at which time it was strongly acid to litmus, and to the eye presented a dull cloudy appearance. A closer examination showed that there were thousands of little fibres, about the eighth of an inch in length, which the microscope exhibited as fibrinous casts of uriniferous tubes, (!) with minute lozenge-shaped crystals of uric acid adhering to their sides. On the addition of a few drops of hydrochloric acid quite an abundant deposit was thrown down, which presented the beautiful variety of colors peculiar to these crystals

In the vessel could be seen a copious deposit of uric acid in the form of yellow sand, while above it floated a cloud of mucus and the urate of ammonia. The urine above the cloud was filled with floating particles of yellowish sand, which seemed to be gradually settling to the bottom, presenting the appearance of a free admixture of ginger and water. Specimens of the sand were examined by heat, acids, and the microscope, carefully enough to determine that it was uric acid of the nucleated form of crystals, with the obtuse angles rounded so as to make an elliptical figure

Urine yielded abundant crystals on the addition of nitric acid ; these crystals had the fine satin-like lustre peculiar to the nitrate of urea, and were deposited without previous evaporation of the urine, which indicates that urea was largely in excess

Sexual Organs p. 302

Male. Pain and tenderness in testicles

Pain and retraction in right spermatic cord

Drawing pain along right spermatic cord

Female. Leucorrhcea and chronic inflammation and congestion of uterus cured during the proving, while no other symptoms were observed on the provers until disappearance of the uterine disease

(Leucorrhcea of long standing cured during a week's proving)

Bruised, sore feeling in vagina (second day)

* During menses, very severe bearing-down, forcing pains

Labor-pains ceased entirely for thirty-six hours (after two hours)

Taken unwell in the morning; wandering pain in back and around through hips, inside, lasting all morning, quite severe at 10, when she was obliged to lie down ; has never had so much pain during menses; flow more profuse since 5 p.m. (second day)

Menorrhagia

Suppression of menses

Respiratory Organs p. 302

Larynx and Bronchi. Constant inclination to cough, from tickling in the larynx, increased by speaking

Constant inclination to cough for half an hour, caused by a tickling sensation in the larynx, which almost prevents speaking, at 7.30 p.m.; an attempt to speak is followed by an inclination to cough (fourth day)

Sensation of slight contraction in the bronchial tubes, which rendered expiration somewhat difficult, after a full inspiration (after six hours)

Voice. Hoarseness (fourth day),4; (after nine hours and a half)

Hoarseness after rising (second day)

Hoarseness, more towards night

Hoarseness and roughness of throat

Hoarseness, roughness, and scraping in the throat

Hoarseness, with roughness and scraping of the throat

Hoarseness; unpleasant fulness in pharynx (third day)

Slight hoarseness (fifth day)

Cough. Dry cough of long standing cured after short irritation of throat and expectoration

Dry, short, hacking cough, night and day, for two weeks

Slight dry cough four or five times, produced by tickling in larynx (after nine hours and a half)

Short dry cough

Short dry cough several times during the evening, caused by tickling in the larynx (third day)

Respiration. Offensive breath? 10.

Offensive breath

Decidedly quickened respiration on waking

Difficult respiration after slight exertion, with general feeling of illness

Chest p. 302

Slight pain in chest

Soreness of the chest (second day)

Lancinating pain along cartilages of false ribs, increased by inspiration

Lancinating pain along the cartilages of the false ribs, increased by taking a long inspiration, soon after waking, at 3 a.m. The same pain, very severe and piercing, so as almost to prevent inspiration for a short time, immediately after retiring, between 10 and 11 p.m., and continuing for half an hour

Prickling sensations during the day in the (female) mammae, with cold chills

Sides. Pain in the left side of the chest

* A catching pain in the left side, just where the heart is, which comes on when she bends her body forward, sometimes when sitting still at dinner and after dinner

Acute pain in right lung, from apex to base, to the right of the sternum, aggravated by inspiration

Acute pain in right lung, extending from apex to base', about two inches to the right of the sternum, aggravated by every inspiration, continuing for two hours, and gradually diminishing in intensity until after retiring ; similar pain next morning, for half an hour, but much less severe (second day)

Heart and Pulse p. 303

Preecordium. *Pain in region of heart, followed by slight palpitation ; at the sixth hour the pain was felt all the time, and accompanied by frequent paroxysms of palpitation

Stitches in the region of the heart or in the heart

Heart's Action. Palpitation and faintness

Pulse. Pulse quick and weak

Pulse feeble and accelerated

Pulse increased twelve beats (after three hours)

* Pulse 70 or 80, irregular (after one hour)

Pulse ranged at about 80 (15-drop doses)

Pulse 86, full, hard, and irregular (after twenty minutes)

Pulse too slow, every third or fourth pulsation intermitting (second day)

Pulse too slow, every third or fourth beat intermitting

Pulse fallen from 78 to 72 (after one hour)

Pulse went down to 69 (after six hours)

Depression of the pulse, which remains for a considerable time

The pulse is considerably lowered, and is apt to remain so for some time

Pulse very weak, with general feeling of lassitude and weakness, with heat and smarting of the face (after third dose)

Pulse weaker and very irregular; 80 to the minute (after three-quarters of an hour)

Feeble pulse (during the first twelve hours)

In the morning, pulse feeble, with weakness and trembling

Pulse small

Neck and Back p. 303

ITech. Stiffness of neck

Stiffness of neck, in evening

Rheumatic pains in the muscles of the neck and back ; a feeling of stiffness and contraction

Cramping in the muscles of the neck on moving the head, first in the left, afterwards in the right side

Sack. Trembling and weakness in the back

Pain as of boils in the back, small of back, and extremities

Terrible backache (second day)

Symptoms of the back, etc., felt for several days

Backache better from pressure (second day)

Dorsal. Pain below left scapula

Occasional slight pain in either scapula and right shoulder

Occasional slight pains in either scapulae and left shoulder

Dull pain behind right scapula

Dull pain in region of lower dorsal and upper lumbar vertebrae

* In the morning, on bending the neck forward, a severe drawingtensive pain at the points of the spinous processes of the three upper dorsal vertebrae, which continued for several hours

Drawing pain in a single muscle between the right scapula and spine, for some hours

Stitches in back, a little below the right scapula and spine

Lumbar. Lame, tired feeling in the back, extending from the region of the kidneys to the sacrum, relieved by rest and increased by motion

* Weight and pain in the lumbar and sacral regions, sometimes extending all around the body, somewhat below the crest of the ilium

Feeling of weight in the small of the back

Weak trembling pain in the small of the back

In early morning, dull pain in small of back, both sides of spine

A dull heavy pain in the back, in the region of the right kidney ; this pain (after twenty minutes) was continuous and increased by motion

Dull, heavy aching in small of back, extending towards the sacrum

Extremities in General p. 303

Objective Trembling in the limbs ; scarcely able to walk

* Twitching of the fingers and toes (second day)

Subjective. *An "uneasy feeling amounting to almost an ache ," through all the extremities every time she took it, which would continue from one to three or four hours

Pains in the extremities

Pain in the extremities, as of boils, with fulness of the head on left side

Restless, drawing sensation in the extremities

Pain in all the limbs (second day)

Rheumatic pains in the muscles of the arms and legs, of a drawing character

Pain in right arm, elbow, wrist, and in the knee, extending down to the ankle

In morning, his joints felt, on motion, as if he had labored exceedingly hard the previous day; joints felt stiff for a day after

Superior Extremities p. 304

Severe pains in the arms, with a numbing sensation, as if a nerve had been compressed. These pains were first felt in the shoulder, and passed down the arm, and then the forearm, producing a very peculiar lame, numb, and sometimes cramping sensation. Similar pains in the legs, but more severe and constant in the upper part of the thigh, about the hip-joint and inguinal region. Slight rheumatic pains all next day

Dull pain, in the right arm, in the muscles, from the shoulders to the wrist

Dull pain in right arm, deep in the muscles, extending from the shoulder to the wrist, continuing during the next day

Elbow. Laming, aching pain in left elbow-joint, anteriorly

Wrist. Lameness of left wrist

Pains in wrist and right elbow, which had continued all day, were relieved

Hand. Hands and forearms weak and trembling; cannot grasp anything firmly; later, hands and feet cold as death, with general chilliness

Fingers Trembling of the fingers when writing

Lameness and inability to flex the second finger of left hand

Inferior Extremities p. 304

Rheumatic pain in left leg

Thigh. Constriction of left sartorius muscle

Knee. Rheumatic pain in kneejoint

Leg. Lameness in right leg, worse when bending forward; soreness and stiffness, moved forward to inside of ankle (second day)

While walking out of doors, sense of aching and shortening in the tendo Achillis (left leg), (second day)

Towards evening, soreness, aching, and stiffness in region of tendo Achillis, aggravated by walking (second day)

Ankle. Sharp wandering pains in left ankle and scapula (after twenty minutes)

Excruciating pain in left external malleolus and left forearm

Foot. Feeling in foot as if it had been compressed

Toes. *Pain in right great toe (second day)

* Dull aching-burning pain in second joint of right great toe

* Dull burning-aching pain in second joint of right great toe, extending up the limb, continuing an hour, from 8 to 9 P.M. The same pain at the same time the next evening, but not extending up the limb. The same pain, less severe, on the third evening

Stinging of left great toe for a few moments on the lower surface, and afterward on the upper, in the afternoon

Generalities p. 304

Objective Nervous shuddering through upper and back part of body

Very trembling

* Tremors all over (after third dose)

* After going to bed, jerking commenced on the side on which he was lying, obliging him to change his position; it began by a perceptible twitching in the left foot

Easily fatigued, as after great exertion

Weak, trembling, exhausted, sinking feeling, with slight nausea

Nervous weakness, afternoon

Prostration (during the first twelve hours)

Restlessness Restlessness

Restlessness, afternoon, moving about, not knowing what to do

* Continual restlessness during the forenoon; desire to move about, not knowing where to go, or what to do

Restless the latter part of the night

During night, very restless

Nervous uneasiness, during the afternoon (second day)

* The general uneasiness and disturbance in the whole system ivas such that it was difficult to fix the attention on any subject oj business or study

Uneasy feeling, hardly amounting to pain, in all parts, principally the right side

All day nervous, Ml of work, and doing it fast

Sensibility. Sensitiveness to cold air

Great sensitiveness to cold air, which seemed to penetrate the system (second day)

Subjective. .Desire to lie down and close the eyes

General feeling of weariness, weakness, and prostration, as if from over-exercise

Feels tired

Feels very tired

Feels very tired and worn out (fourth day)

Feeling of exhaustion, as from over-exercise

Sensation as if from severe muscular exercise, especially in the small of the back

Feeling, which only those know who "spree "court or watch all night with the sick

Feels bad generally (third day)

General feeling of illness

In morning, general feeling of lameness, and many unenviable feelings, which he thinks the feeling on getting over a "spree would hardly express, unless it was a pretty hard case

Sick all over ; so weak and trembling as not to be able to go out or study ; believes the condition to be but one remove from mania-a-potu ; next morning weak and trembling (after fourth dose)

* Soreness and stuffiness of whole body, as after hard labor

* General bruised feeling, as if sore

Peculiar tingling in the muscles, followed by an aching pain in the limbs, from above downward

Affects the left side most

Skill p. 305

Eruptions Dry. Small red papilla? first appeared, becoming a diffused redness

Eruptions, Pustular. Single pimples on the back of the hand, with a little pus at the apex

In morning, soon after rising, observed a single pimple on dorsal surface of left hand ; it was larger, but similar in appearance to those produced two mouths since; a little pus secreted at its apex; after three or four days it disappeared (second day)

Ulcers. Ulcer on inner surface of lower lip

Small ulcer on inner surface of lower lip

Subjective. Itching of the back of the hand and wrist

Itching and redness of the back of the hand

Itching and redness of the dorsal surface of the right hand, in the afternoon, and especially in the evening

Itching of the dorsal surface of the left hand and wrist, particularly on the dorsal surface of the thumb, in the evening; small red papulae first appeared, becoming, after slight irritation, a diffused redness, which disappeared in a few hours, but could be reproduced at any time by slightly irritating the surface; this symptom gradually disappeared in a few days

Sleep and Dreams p. 305

Sleepiness. Very sleepy (second day)

In afternoon, felt as if he could not keep awake, but must lie down and go to sleep

Drowsiness, with creeping chills upon the back, during the evening, followed by frequent wakings during the night, and desire to throw off the bedclothes, although the thermometer was below zero

So drowsy that he laid down and soon fell asleep, and remained in this state an hour (after two hours)

Sleeplessness. During the night, slept well for three or four hours, then restless

Sleep very restless

Disturbed, restless, unrefreshing sleep from 3 to 5 A.M., with disposition to fold the arms overthe head (second day)

Frequent wakings during the night, and a copious, papescent stool in the morning

Frequent wakings during the night, during some of which there were flushes of heat, and desire to throw off the bedclothes, when the thermometer was below zero

Cannot sleep

Fever p. 305

20 at night ( fourth day),15-

Dreams. Troublesome dreams

* Unpleasant dreams of being in trouble, of being in a sad plight

Fever p. 306

Surface of the body, together with that of the face and hands, became cool and dry (after six hours)

Chilliness in the forenoon

Afternoon chilliness (second day)

Cold chilliness, with cold hands and feet

Chilly, in bed before rising (third day)

General, internal], nervous, chilly feeling all over, but less over the back

Cold chills, with prickling sensations in the breasts

Cold chills and prickings in the female mammae

Occasional cold chill

Coldness and chills, especially of the arms and feet

Soon after waking, in morning, whole surface became cold

Soon after waking, at 3 a.m., the whole surface became cold ; slight cold perspiration, and sensation as if it would become profuse, continuing for an hour, accompanied by lancinating pain along the cartilages of the false ribs left side, increased by taking a long inspiration (second day)

During afternoon, chilliness in back

Heat. Heat in front part of head

Heat in left side of face, with lassitude all over

Increased heat of face ; slight inclination to sweat ; pulse rather full, and 90 in the minute, it being nearly 80 before taking the drug (after three-quarters of an hour)

Flashes of heat in cheeks

Heat, pain, and weariness in the region of the kidneys (second day)

Sneat. Disposition to perspire at night, for three weeks

Perspiration, headache, similar to morning sickness during pregnancy, etc.,10.

Slight cold perspiration, with lancing pain along cartilages of false ribs, increased by inspiration

Skin dry and hot

Cold sweat on hands and feet (third day)

Conditions p. 306

Aggravation.

(Morning), On waking, pain in head; on getting up, dull headache ; before breakfast, pain in forehead ; on waking, at 2 oclock, pain in forehead, etc.; after rising, pains in vertex, etc.; on rising, pain in eyeballs, etc.; after rising, coryza ; dry mouth; before eating, faintness at epigastrium; before breakfast, pain in epigastrium, etc. ; after breakfast, sense of tremor in stomach ; after rising, disposition to diarrhoea ; papescent stools; stitches in urethra; on waking, quickened respiration ; on bending neck forwards, pain at points of spinous processes of vertebrae ; early, pain in small of back ; feeling in joints ; from 3 to 5 oclock, disturbed sleep, etc. ; in bed, before rising, chilly ; soon after waking, surface cold.

(Forenoon), At 9 oclock, headache ; at 10 oclock, aching of eyes; eyeballs painful ; coryza; at 10 oclock, feeling in malar bones, etc.; sense of aching along oesophagus ; faintness in epigastrium ; at 10 oclock, rumbling in abdomen; restlessness; chilliness.

(Afternoon), Depression, etc.; pain in head; dull pain in forehead; pain in eyelid; at 4 oclock, sneezing; inclination to sneeze ; uneasiness in teeth ; at 4 oclock, dryness of pharynx; sensation in stomach; towards evening, soreness, etc. ; in region of tendo Achillis; stinging of great toe; nervous weakness; itching on hand; chilliness; chilliness in back.

(During forenoon and part of afternoon), Dull pain in head.

(Evening), Pain in head ; at 10 oclock, pain in forehead, etc.; fulness in vertex; after retiring for the night, pain in eyeball; obstruction of nostril; stinging in nose; sore throat; towards night, hoarseness ; at supper, no appetite ; at 10 oclock, rumbling of flatus ; at 10 oclock, flatulence ; disposition to diarrhoea ; dry cough ; stiffness of neck ; from 8 to 9 oclock, pain in great toe; after going to bed, jerking; feeling of lameness, etc.; itching, etc., on hands; drowsiness.

(Afternoon and evening), Pain in vertex.

(Night), Pain from eyeball through occiput ; dryness of pharynx, etc. ; restlessness ; disposition to perspire.

(Bending forward), Lameness in leg.

(After hearty dinner), Frontal headache.

(Inspiration), Pain along cartilages of ribs; pain in lung; pain in hypochondriac region.

(During menses), Forcing pains

(Motion), All symptoms ; soreness m occipital region ; pain in hypochondriac region ; fame, etc., feeling in back.

( Outdoors), Frontal headache ; while walking, aching, etc., in tendo Achillis.

(Speaking), Inclination to cough.

(After supper), Pain in epigastrium.

( Walking \, Soreness, etc., in region of tendo Achillis.

Amelioration p. 307

( Open air), Pain in head ; pain over eye

(Eating), For a time, seemed to relieve all symptoms.

(Pressure), Backache

(Best), Lame, etc., feeling in back.

(In room), Headache in frontal region.

(After stool), Colic.

(Supper), Nausea, etc.

Footnotes

† Original not to be found. j This resume would seem to include much of Dr. Paine's provings, many of the groups of symptoms being identical in expression and sequence ; Drs. Hill and Douglass furnish no details of doses, nor day-books. — Editor.