Croton Tiglium

Croton tiglium, Linn. (Tiglium officinale, Klotzsch). Natural order, Euphorbiaceae. Common names of seeds, Croton oil seeds, Puergirkorner, Pinones de Maluco, Grames de Til ley, Petit Pignon dTnde.

Preparation, Tincture of the oil from the seeds.

Authorities. 1, Herrmann, Praktischen Mitt, (from Roth's Mat. Med.); 2, a girl, aged 25, took one drop on sugar, from Buchner's collection, Archiv. f. Horn. Heil, 19, 116; 3, effects of one drop on a young, black-haired girl, ibid.; 4, effects of three drops on a girl, aged 26, with carious teeth, ibid.; 5, effects of three drops on another girl, ibid.; 6, effects of three drops on a girl of 36 (taken for urticaria), ibid. ; 7, effects of three drops triturated with sugar, and taken in three doses, on a girl aged 26, ibid. ; 8, effect of three drops on a student, aged 23, ibid. ; 9, a girl, aged 20, took one-eighth of a drop daily, afterward three-eighths, afterward one-half, and again three-fourths of a drop daily, ibid. ; 10, a man, aged 32, took one drop on sugar, ibid.; 11, Dr. S.T.,aged 26, took repeated doses of three-tenths, one-half, three-fourths of a drop, and one drop, ibid. ; 12, a girl, a^ed 32 took one-half a drop for several days, afterward three-fourths of a drop' ibid. ; 13, K. M., aged 26, effects of smelling a solution of two drops to 100 of Al., afterward of the pure oil, and of taking two or three drop doses, ibid.; 14, B., a man, aged 27, took numerous doses of from one-tenth to one drop each, during a period of about seven weeks, ibid. ; 15, effects on a girl of lo of rubbing five drops on the arm, ibid. ; 16, Commensur. Jour d. Pharm., 18, p. 394, effects of getting some into the eye, ibid. ; 17, Tavernier, Froriep's Noticed, 12, p. 287, rubbed some oil about the umbilicus, ibid. ; 18, C. M., rubbed some oil over the left deltoid muscle, and afterward a little below the same place, ibid.; 19, the same, effects of the fumes inhaled while rubbing the oil into the arm ; 20, the same, effects of rubbing od above the umbilicus; 21, Dr. Joret, effects of one or two drops taken internally (Archiv. Gen. de Med., 1833), A. H. Z., 4, p. 69; 22, A. H. Z., Mon. BL, 9, p. 62, a man drank some by mistake, taking about half an ounce ; 23, Rump, effects of whole plant, especially of the leaves, Herb. Amboin, t. 4, p. 98, from Wibmer; 24, Buchner, effects of chewing aud spitting out a seed, Toxicologic, 1827, from Wibmer; 25, Wibmer, effects of one drop made into two pills, taken with an interval of half an hour; 26, Laudsberg, effects of half a large seed, Pharmacog. Euphorb. Diss. Berol., 1831, from Wibmer; 27, same, effects of one drop on sugar; 28, same, effects of rubbing oil into the abdomen; 29, Hence, effects of rubbing oil into umbilical region, Archiv. f. Horn. 20, 2, 183 ; 30, same, proving with 2d trit. of seeds; 31, Dr. Renter, proving with 15th dil., ibid.; 32, same, provings with 4th dil. ; 33, Connell, general effects, from Buchner's collection, Archiv. Horn., 19, 1, 119 ; 34, Piedagnel, general effects, ibid. ; 35, Meinel, effects of rubbing oil into inguinal region, Fr. Mag., 4, 966 (from Deutsche KL, 1851) ; 36, Guttseit, effect of two drops, repeated after two days, for obstinate constipation, Fr. Mag., 4, 274 (from Med. Zeit., 1846); 37, Graefe and Walter, effects of one drop, Fr. Mag., 1, 592 (Rust's Mag., 1836) ; 38, Hutchinson, general effects of rubbing in six drops on the skin, Bost. Med. and Surg. Jour., 8, 411 ; 39, effects of two drops, taken for scanty menstruation, from the last ; 40, Pereira, effects of the dust encountered while emptying packages of the seeds, Mat. Med., 2, 1, 606; 41, Prujer, Rust's Mag., 19, 3, 525, from Roth's collection (Mat. Med.) ; 42, Koller, Rust's Mag., 46, p. 45, ibid. ; 43, Romberg, Casp. Wochen., 1835, ibid. ; 44, Brandes, Hufel. Journ., 57, p. 120, ibid. ; 45, omitted ; 46, Horn's Archiv., 60, p. 574, ibid. ; 47, Murray, App. Med., 4, 150, ibid. ; 48, Choanse, Act. nat. cur., 9, p. 39, ibid. ; 49, Bouet, Axille Med., 1845, ibid. ; 50, Vautherin, effects of inunction of stomach with twelve drops, Monograph des Graines de Crot. Tig., Paris, 1864; 51, Med.- Chir. Rev., July, 1834 (All. Med. Zeit.), general effects of external use ; 52, Mayer and Halle, poisoning of three persons by strawberries impregnated with the oil, Ann. d'Hyg., 35, 193 ; 53, Maurezin, poisoning of a girl of 6 years by three grammes in " cafe au lait," Gaz. des Hop., June, 1868 ; 54, omitted ; 55, C. C. Shayer, general account of poisoning of five persons by eating some birds over which some Crot. oil had been spilled, Am. J. of Med. Sci., Jan., 1867 (the birds had been well washed previous to cooking) ; 56, Tilbury Fox, general effects of inunction, Lancet, April, 1867 ; 57, S. R. Percy, general effects of internal and external use, Am. Med. Times, 5, 170 ; 58, Bryon, effects of a teaspoonful of a mixture of equal parts of Croton aud olive oil, Ed. Med. Jour., 1861 ; 59, J. L. Bunting, poisoning of a woman by one ounce, Med. Record, 3, 274 (Boston Med. and Surg. Jour.) ; 60, Keith, effects of a teaspoonful on a boy, given by mistake in hooping-cough (Ed. Med. Jour.), from Br. J. of Horn., 2, 129; 61 Berridge, proving on a man with several doses of the 200th dil., Lehrman (A. J. of H. M. M., 1874, p. 128) ; 62, Marchand, proving on self with two pills of Croton oil taken in bread, " Du Croton Tiglium, Pans, 1861 ; 63, Vautherin, effects of eight or ten drops taken by mistake with food, " Des Graines de Croton Tiglium," Paris, 1864, p. 88.

Mind p. 608

Emotional. Disinclined to speak ; uttering no complaints (after three hours),™.

Sadness

Great depression of spirits

Anxiety

Great an diet)T,13 ; (after one hour)

A peculiar feeling of anxiety, as though some misfortune were about to happen

Solicitous mood

Fretful

Peevishness and fretfulness ; everything is unpleasant to him

Morose mood

He is very morose and dissatisfied

Intellectual. He has no inclination to work ; would much rather dance than attend to his business

Thought difficult

Loss of memory

Head p. 608

Confusion and Vertigo. Confusion of the head

Confusion in the head, especially in the temples

Confusion of the head, immediately on rising

Confusion of the head, with dulnessand pressure in the forehead

Confusion of the head, but especially of the frontal region, with pressure and heaviness

Confusion of the head, especially on the right side, with pressure downward from the vertex, so that there is sometimes sticking extending downward below the ear, with impaired hearing in the right ear

Confusion of the whole head, lasting through the night

Confusion of the whole head, on going into the open air

Great confusion of the head with the vomiting, which also lasted three days, with loss of appetite

Great confusion of the whole head, with pressure towards the frontal region, and nausea

Head very much confused

Confusion of the forepart of the head, especially of the frontal region

Confusion of the forehead

Confusion of the left half of the occiput

Confusion of the occiput

Vertigo

Vertigo, so that she could scarcely remain sitting, especially on looking up

Vertigo and confusion of the head, lasting all the afternoon

Vertigo, especially on the right side, with pressure in the right eye

Vertigo, with nausea, so that she was obliged to go into the open air, where she became worse, looked pale, seemed very weak and exhausted

Attacks of vertigo, while walking in the open air

Head felt dizzy

Dizziness of the forehead

He became very giddy and fell down insensible

Gen eral Head. Head feels as after intoxicating drinks

Heaviness of the head (in half an hour)

Heaviness and confusion of the whole head, with prickling in the eyes

Head heavy, dull, and confused, in the morning, on waking

Pains in the head, especially worse in the middle of the day, and particularly for a few hours after dinner

Headache, day and night, for three days, affecting the anterior and upper part of head ; it is dull, continuous, and very confusing ; not affected by rest or work

Headache, as from disordered stomach

Headache, with confusion, followed by general heat and copious sweat

Violent headache

Burning pain in the head

Feeling of fulness of the head

Head full and confused, with heaviness of the forehead

Head very full and heavy, so that she was unable to read

Congestion seems to rise from the abdomen to the head, with warmth of the skin and sweat

Sticking headache, extending to the vertex (second day)

Sticking twitching in the head

Sensitiveness of the head ; the weight of his hat gives him a headache when out walking (which had not happened previously). When he took off his hat, the headache stopped (in an hour and a half) 1

Jerking in the head

Forehead. Pain in the forehead, with tearing extending to the right temple, where it remains for two hours as a sticking pain 12

Slight pain in the forehead, relieved after keeping quiet for half an hour 31

Violent pains in the forehead, with throbbing tension and pressure outwards, and general confusion of the head, aggravated bv taking some beer and bread

Fulness and pressure in the frontal region 13

Tensive pain m the forehead, with pressure and sticking

Pressure iu the forehead .

Pressure in the right side of the forehead aud temporal region

1 pressive pain iu the left half of the forehead

Sticking in the forehead, while walking

Temples. Pain in the left temporal region, as it burnt with hot coals

Pressure in the temples

Sticking iu the left temple

Twinging pain in the temples

Vertex. Tearing in the head, towards the vertex

Sides. Sticking, as from needles, in the right side of the brain, above the eye

Occiput. Pressive headache in the occiput

External Head. Prickling in the scalp on the vertex

drawing in the occiput,14. t Eye

Objective. Eyes quite bright, peculiar at times

Violent inflammation of one eye

Violent ophthalmia and inflammation of penis and scrotum, iu consequence of inadvertently carrying the fingers (after applying the drug) to the eyes and genital organs (two cases)

Subjective Heaviness, weakness of the eyes

Violent pains in the eye (local effect)

Violent pains, followed by swelling of the whole eye and side of the face (from some of the oil getting into the eye)

Sticking in the middle of the left eye, and afterwards some indications of it in the right

Orbit. Slight tensive pain above the right orbit, with pressure in the right side of the occiput

Lids. Violent twitching of the eyelids

Cramplike pain in the right eyelids, especially towards the external canthus

Jerking sticking in the right external canthus, with frequent contraction aud twitching of the whole eye

Lachrymal Apparatus. Running of water from the eyes and nose

* Copious lirJiryinatlo)i,w.

Conjunctiva. Inflammatory redness of the conjunctiva of the left eye

Ball. Sticking in the left eyeball

Pupil. Pupils dilated

Vision. Vision impaired, with staring, glittering eyes

Sight dim, as if there were smoke in the room

The sight vanishes easily

Sight vanishes easily, as though a veil were before the eyes

Vision vanishes in the room, with slight vertigo

Fog before the right eye, followed by weakness of it

Ears p. 609

Sticking beneath the left ear

Dragging and twisting sensation towards the orifices of both ears

Dull dragging pain towards the orifices of both ears

Twinging pain in the left ear

* Spasmodic twinging pains deep within the left ear

Heaving. Roaring in the ears

Roaring in the ears, and a kind of vertigo ; he Avas unable to stand from fear of falling

Hearing and sight disappeared with the nausea

Nose p. 609

Objective. Increased secretion from the mucous membrane of the nose (after smelling the oil)

Coryza, with slight discharge from the nose, lasting some days

Coryza, with slight watery discharge

Subjective. Dryness of the nose and throat

Burning in the right nostril, obliging him to rub it (in three hours and three-quarters)

Burning sensation in the nose and mouth

Drawing pains, extending through the nose to the root, and thence into the brain

Constant irritation in the nose and in the conjunctiva of the eyes (from the fumes of the oil)

Face p. 609

Objective. Countenance distressed

Face expressive of fatigue and debility

Countenance pale and rather shrunk (after threequarters of an hour)

Face pale, with sensation of coldness

Slight jaundice color

Face, hands, and toes cyanotic

Swelling of the face aud hands (from triturating the grains in a mortar)

Swelling and redness of the face and eyelids, which are covered with small vesicles-

Mouth p. 609

39 (from the effluvia)

Subjective. Increased warmth and burning in the right half of the face, starting from the corner of the mouth

An illusory sensation, as though insects were creeping on the face

Lips. Lips swell and become quite sore (external application), (1 or 2 drops)

Lips dry, cracked

Lips dry and tense, in the evening

Burning in the angle of the mouth, with slight swelling on the outer border, lasting several days

Tension in the corner of the mouth

Mouth p. 610

Teeth. Drawing in the right lower eye-tooth

Sore pain in the left molar of the lower jaw on chewing

Gams. Painful swelling of the gum of the inner side of the right upper jaw

Gum bleeds easily in the morning while washing

Tongue. Tongue white, showing impress of teeth (one case), (after eighteen hours)

Tongue coated white

Tongue red, smooth, glistening, and dry in centre (second day)

Tongue furred and dry (second day)

An eruption plainly visible at the root of the tongue, on the soft palate, and on the posterior wall of the pharynx (third day)

Swelling and numbness of the tongue

Burning and sensation of contraction at the tongue and pharynx (during twenty -four hours)

Sensation of peppery heat, at first not very marked, but gradually increasing, successively felt on the palate, uvula, isthmus faucium, pharynx, tongue, and lips (after a few seconds)

He stated that his tongue felt too large for his mouth, and appeared to be without feeling, and he had bitten it two or three times to ascertain whether there was any sensation in it. On examination, however, no change could be observed in the size or appearance of the tongue or parts about the mouth

Tickling painful sensation in the tip of the tongue

Feeling as though the tip of the tongue were electrically sensitive, with a sweetish bitter taste

General Mouth. Inflammation of the mouth, lips, and pharynx

Swelling of the palate for several days

Some vesicles in the mouth on the hard palate

Some pustules in mouth (with return of burning in mouth and throat), (one case), (after eighteen hours)

Dryness of the mouth

Dryness of the mouth, without thirst (in half an hour)

Dryness in the mouth, with scraping sensation in the throat

Complains of his mouth being parched

Burning in mouth and throat (after one hour)

Burning sensation in mouth and pharynx

Mouth feels as if burnt

Burning scraping in the mouth and throat, extending low down into the oesophagus, not relieved as formerly by cold water, lasting over two hours (soon)

Saliva. Increased secretion of saliva,1314; (after one hour),62; (after four hours)

Profuse salivation, soon

Profuse secretion of saliva and mucus

•Collection of water in the mouth

Taste. Taste at first agreeable, like chocolate; but soon followed by the peculiar burning (effects of the roasted seed)

Taste at first sweetish, afterwards extremely bitter and burning; the scraping-burning taste was coincident with increased warmth and accumulation of saliva

Acrid burning taste in mouth and throat (1 or 2 drops)

Taste sometimes burning, sometimes scraping (from a drop of the oil)

Taste flat

Nauseous, flat taste

Taste pasty

Bad taste (immediately)54; (second day)

Sharp sour taste rising up from the stomach

The burning sensation has risen above the entrance of oesophagus, and is accompanied by a remarkably acrid taste in the back of the mouth, like pimento (after one hour)

Somewhat bitter taste in the mouth (immediately)

Taste as after almonds,14. Water tastes flat and nauseous, and causes a feeling of emptiness ; he drinks very little on account of a severe burning in the throat,13. Aa^ft r0(*!l

Ofyectwe. Redness and smarting of the throat (third W 'L !'°at rv and sore (second dav)

Hawking of mucus, which nas a sour taste, like vinegar

Subjective. Dryness in the throat, with sense of increased irritation of the pharynx, during inspiration, almost like a slight pharyngeal angina (in twenty-four hours)

Throat dry.

Ration as though a morsel were in the throat, which he was unable to nf! "nSj?^ throat (soon),6».-Burning in the throat,11 ; (immediate u uJ f Urning in the throat and stomach

Burning in the throat, as ri he had eaten pepper

Burning and contraction of the throat and tongue

Constant burning and contraction of the throat

Sensitive burning and scraping in the throat

Burning pain in the throat/

intense burning sensation in the throat, and all down the oesophagus (after half an hour)

Feeling of warmth in the throat, and along the oesophagus, sometimes extending to the pit of the stomach and lasting several minutes (immediately)

Complaints that his throat was swell- 1Ug', •

b7aPlng lu the throat

Scraping in the throat, lasting six hours

scraping in the throat, causing frequent hawking

Scraping at the throat, worse during an expiration

Scraping in the throat, followed by burning in the chest

Slight scraping in the throat, with sensation ot warmth in the back of the mouth, lasting half an hour, disappearing after cold water (soon)

Burning scraping in the throat and fauces

Rawness in the throat

Intolerably acrid sensation in the throat and all down the oesophagus

Jerking and shooting through the throat

Scraping tingling in the throat

Tickling followed by scraping and then burning, at the point where the hard and soft palates unite (soon)

Uvula and Tonsils. Redness and elongation of the uvula, u.

Swelling of the tonsils, painful to external pressure

Titillation in the right tonsil (in a quarter of an hour)

Fauces, Pharynx, and CEsophay US. Increased warmth in the fauces

Burning in the fauces ; relieved on inspiration; aggravated by expiration

Scraping in the fauces, followed by burning, and afterwards tickling in the larynx

■ Feeling of warmth along the pharynx and oesophagus, extending to the pit of the stomach, lasting several minutes (soon)

Burning in the pharynx and bowels (from the effluvia)

Burning in the pharynx (again on the second day), allayed a little by drinking water

Acrid sensation in pharynx

Severe pain in the oesophagus (soon)

Burning extending up the oesophagus,14 ; (after three-quarters of an hour)

Prickling at the entrance of the oesophagus (while swallowing the dose)

Frequent inclination to swallow, which always causes pain on the left side of the oesophagus, as though a small ball were being pressed through its wall

Constant irresistible inclination to swallow saliva, with a sensitive pain deep in the oesophagus, as if a small ball were being pressed out of the left side, lasting half an hour, relieved after cold water

Swallowing. Difficult swallowing

External Throat. Swelling of the submaxillary glands, painful to touch

Stomach p. 611

Appetite. Very great appetite, after the pains had entirely ceased

Hunger, without appetite

Unnatural hunger, with emptiness of the stomach

Appetite diminished

Appetite and thirst very slight

Loss of appetite,9 12 40.

Loss fall appetite

Little appetite at lunch, with feeling of repletion after eating very little (after six hours)

Loathing of his usual breakfast, soup a lean (in eleven hours)

Although without appetite, and even with a feeling of fulness, he eats his usual allowance at luuchtime (after five hours)

Thirst. Considerable thirst (second day)

Thirst intense,150; (after one hour)

Aversion to beer

Eructation and Hiccough. Eructations,9"; (after one, two, and four hours)/.

Eructations of water in her mouth

Eructations, nausea, and weakness

Constant eructations of water from the stomach

Empty eructations

Empty eructations, especially in the afternoon

Empty eructations followed by nausea

Acrid and burning eructations

Watery eructations

Bilious eructations, in the evening

Hiccough, yawning

Heartburn, Heartburn

Heartburn, with some nausea; after dinner

Nausea and Vomiting, Nausea,38; (after one hour),12, etc.

Nausea and vertigo, increased in the open air

Nausea with collection of sour water in the mouth

Nausea and eructations

Nausea and eructations after every drink

Nausea and desire to vomit (after half an hour)

Nausea with inclination to vomit, after taking some milk

Nausea and vomiting (larger doses)

At times nausea, seldom vomiting; the latter especially in women

Constant nausea, with accumulation of water and saliva in the mouth, with slight chilliness

Unusual nausea

Sleep sound until midnight, after which it was disturbed by much nausea, followed by sudden vomiting of a sour, exceedingly strongsmelling fluid in rather large quantity; after the vomiting, diarrhoea, with a feeling as though a fluid were swashing about in the abdomen

Great nausea

Great nausea, as if to vomit

Insufferable nausea, with inflation of the bowels and borborygmi in the epigastric region (fu three hours and a half')

Continual inclination to vomit, which he tries to restrain (in half an hour)

Retching, with vomiting of food and some water

Frequent retching, with accumulation of water in the mouth

Violent retching and vomiting, with rumbling in the abdomen and diarrhoea

Violent retching with very difficult vomiting of yellowish water, of an oily smell, and sweetish-bitter, oily taste (after one hour and a half )

He was obliged to lean against the washstand with all possible force in order to resist the spasmodic retching

Vomiting (one case)

Vomiting followed by diarrhoea

Vomiting, borborygmi, and diarrhoea, twentyfour times in succession

Severe vomiting (after five minutes)

Severe, vomiting (after five minutes) of matter containing numerous streaks of a white, shiny, emulsion-like substance, mixed with clear, glairy fluid (after three-quarters of an hour)

Violent and very copious vomiting, for threequarters of an hour (soon )

Sudden violent vomiting, frequently repeated, of whitish-yellow, frothy liquid ; with most violent contractions of the stomach

Vomiting of light and glairy matter (one case), (after eighteen hours)

Vomiting of a very large quantity of sour, strongly smelling fluid

Vomiting of some water, mucus, and food, with constant nausea, after eating

Vomiting of mucus with a bitter taste

Vomiting of bile

Stomach. Gastro-enteritis (excessive doses)

Rumbling in the stomach, with heaviness on the chest

Anxiety, oppression, anil pressure in theepigastric region, with great nausea

Feeling of warmth and burning in the pit of the stomach

Sensation of emptiness in the stomach (after one hour)

* An unpleasant sensation of emptiness and hunger, <ui(l rumbling in the abdomen (after half an hour)

Empty, hungry sensation

Very empty feeling in the stomach before eating

Sinking in the stomach, with sensation of weakness (after two hours),32. Stomach feels relaxed and is painful to pressure

Epigastric pain for several days

Severe pain in the epigastrium (two cases)

After vomiting had 'continued for a quarter of an hour, she began to complain of severe pain in stomach, not aggravated, however, by pressure

Burning in the stomach

-Burning as from coals in the stomach

Burning and feeling of repletion at the stomach (after ten minutes)

Burning pain at the stomach.41.

Epigastrium felt hot and tense

Fulness and oppression of the stomach at midnight, followed by nausea, and afterwards by easy vomiting of the food eaten at supper; then by sweat of the face and comfortable feeling; after half an hour repeated vomiting of the contents of the stomach, which were somewhat bitter, after which he slept well until morning

Feeling of fulness in the stomach

Feeling of repletion at the stomach, which impedes respiration (in three-quarters of an hour)

Tension in the epigastric region

Constriction in the stomach

Some constriction in the upper part of the stomach

Cramp in the stomach and upper abdomen

Pressure in the stomach,14; (after a quarter of an hour)

Pressure in the epigastric region

Pressure in the pit of the stomach, 9 13 19.

Pressure in the stomach, in the forenoon

Pressure in the stomach, with anxiety

Pressure in the epigastric region, and a feeling of fulness

Pressure and fulness in the region of the stomach and chest

Pressure and constriction in the epigastric region

Pressure at the stomach, which changes into nausea, with accumulation of saliva in the mouth i after a quarter of an hour)

Pressure in the stomach, with discomfort of the abdomen

Pressure in the stomach, with tickling sensation, qualmishness, and slight spasmodic motions, as though one would vomit

Pressure in the pit of the stomach, transient

Some pressure in the stomach

Sense of weight and heat in the epigastrium, such as is felt after drinking strong spirits (after fifteen minutes); the heat seems to radiate in every direction, from one spot ; it is confined to the stomach, and is unpleasant, but not painful (after twenty-five minutes) ; it becomes a burning and extends to the cardia (after half an hour) ; it is relieved for a minute or two by a glass of barley-water

Cuttings in the stomach, afterwards below the stomach, and followed by tearing in the intestines of the right side near the ileum

Cutting pains beneath the stomach

Violent colic in the stomach and abdomen

Scraping in the stomach, followed by slight nausea

Burning scraping extending down into the stomach and along the intestinal tract

Sensitiveness of the epigastric region to touch

Abdomen p. 613

Hypochondria. Pressive pain in the left hypochondria (after nine hours)

Pressure in the region of the spleen

Sticking in the spleen, in the evening

Throbbing in the region of the spleen

Umbilical. Painful movements about the umbilicus, with increased pain on touch or pressure

Dull vermicular movements, with slight gurgling about the umbilicus

Tension between the umbilicus and pit of the stomach

Tension and movement about the navel, with pressure towards the anus, while lying down

* Griping about the umbilicus

Griping and pinching pains in the abdomen, about the umbilicus, extending to the left side of the bowels

Violent, dull, spasmodic pain seated in the umbilical region, more violent while sitting with the abdomen bent over than when erect or when walking

Pressure, with twinging, above the umbilicus

Cutting about the navel, as though two knives were cutting towards each other in the intestines, relieved by two evacuations; after which a watery stool follows, without any disturbance

Cutting pains about the umbilicus

Sticking to the left of the navel

Tearings about the navel, after dinner

Pains about the umbilicus, as though the intestines were twisting, followed by tearing in the left side of the abdomen (after one hour)

Twinging and tension in the umbilicus, on going out, with pressing upward to the epigastric region, and sudden nausea

Coliclike pains about the umbilicus

Colic, so that she could scarcely get her breath ; the cutting pain seemed to be about the navel, extending up to the stomach, and caused her to bend double ; thence it extended to the left side of the abdomen

Very transient colic below the navel, in the evening, with distended abdomen, followed by urging to stool

General Abdomen. Fulness, tension, and rumbling in the abdomens- Flatulent distension of the abdomen, with sensation of heaviness in it .

Abdomen full, with tension of the parietes

* Abdomen full and distended, with griping above the navel

An audible and but slightly felt disturbance of the bowels (after a few minutes), followed by liquid evacuations (after twenty minutes) ; during the six or eight hours that the effect continued, he had fifteen very copious stools

Movements in the intestines become perceptible, accompanied by slight griping pains

* Gurgling in the intestines, as though only water were in them, mostly on the left side

Rumbling in the abdomen,34 ; (after five minutes)

Rumbling and gurgling in the abdomen

Rumbling in the intestines

Rumbling in the intestines, on the leftside

Rumbling and loud noises in the intestines (after half an hour)

Rumbling in the intestines, and emission of offensive flatus, on rising and while rising

Borborygmi (after threequarters of an hour to one hour).21

Borborygmi in the bowels, and several eructations (in an hour and a half)

Flatulence

Flatulence, with slight but frequently recurring coliclike pains

* Flatulence, soon followed by urgent desire for stool; evacuation sudden, with flatulence; stool thin, small (second day)

Much flatulence

Passage of much flatus, in the evening

Easy emission of flatulence, while walking ; indication of speedy stool

Emission of offensive flatus

Frequent emission of offensive flatus

Frequent passage of offensive flatus

Constant desire to pass flatus, which, however, was emitted suddenly

Very urgent desire to pass flatus, while sitting

Movings, rumblings, and gurglings, with painfulness to touch on the navel

Slight movements and retractions, with dragging pains in the upper abdomen and umbilical region, followed by stool

Uneasiness, griping, and twinging in the abdomen

Unpleasant sensation in the intestines, with rumbling in the abdomen, lasting half an hour (after one hour)

Sensation as though diarrhoea would occur (after four days)

An unpleasant feeling in the abdomen, as though diarrhoea would occur

Heaviness and confusion of the whole abdomen, with retracted parietes

Feeling of heaviness in the upper abdomen

Pains in the abdomen

Pains in the abdomen, relieved an hour after eating some gruel

Pains in the abdomen, with passage of much offensive flatus, in the morning, after rising

Pains in the walls of the abdomen, especially deep, so violent that slight pressure or deep inspiration made it intolerable

Pain in bowels (with the nausea), (one case)

Feeling of fulness in the abdomen, with slight griping

Feeling of fulness in the abdomen, with rumbling and slight colic

Violent annoying tension and distension of the whole abdomen, with urging to stool, tenesmus, and emission of offensive flatus from the anus ; these symptoms are worse while sitting than while walking or standing

She seemed to feel distinctly the medicine work downward into the coecum, and cause a contraction ; as it approached the umbilicus, it caused some twinging

Griping in the transverse colon, repeated before every stool

Griping and gurgling, with feeling of fulness in the abdomen, and pressure towards the anus

Slight griping after dinner, transient

Griping pains in the upper abdomen,11 u.

Slight griping pains in the intestines, especially aggravated by touch

Violent griping pains, with rumbling and gurgling rUni t!1** *abdomen> soon followed by emission of offensive flatus

Lo90.J Dragging spasmodic pains in the upper abdomen, especially while sitting, followed by tensive pain

Cutting in the bowels, followed by stool, -. Cutting pains, tenesmus, and alvine evacuation, at first pultaceous, then liquid, mingled with mucus and bile (after two hours), then three more diarrhoeic stools of a greenish-yellow

Cutting pains in the intestines and about the umbilicus

Cutting pains in the bowels, with emission of fetid flatulence (after twelve hours)

Sticking in the ccecum,u.

Tearing in the abdomen, while eating

Tearing in the transverse colon

Twinging and cutting pains, mostly in the colon

Frequent twinging pain in the abdomen

Spasmodic twinging pains in the abdomen and about the umbilicus, while walking

Coliclike pains, with rumbling in the abdomen, and feeling as if diarrhoea would come on, lasting half an hour, and disappearing after passage of flatus (second day)

Violent colicky pains and passage of loud offensive flatus (after six hours)

Pressive coliclike pains in the abdomen

Colic (after one hour)

Colic, generally

Colic, after eating

Colic and tenesmus

Slight colic

Violent colic, after eating, and while walking

Griping colic, with pressure towards the anus

Slight griping colic, with dragging towards the anus

Flatulent colic, in the evening

Flatulent colic, disturbing sleep ; the colic lasted about half an hour, and was relieved after the passage, of much noisy flatus (after six hours)

Slight tenderness of abdomen, but none of epigastrium (one case), (after eighteen hours)

Painful sensitiveness of the abdomen, especially felt on pressing upon it

Soreness in the abdomen on coughing

Whole abdomen sore and easily painful

* Swashing in the intestines, as from water (second day)

Swashing, rumbling, and griping in the intestines

* Feeling as though fluid were sivashing in the abdomen

Hypogastrium and Iliac Region. Very severe pain in lower part of bowels ; not increased by pressure (after two hours)

Pressive pain in the lower abdomen and bladder

An undefined pain in the left inguinal region

Tensive pain in both inguinal regions

Pressive pain above the posterior superior spine of the left ilium

Meet a m and An us.

Rectum. Feeling within the rectum, as though purging would follow

Anus. Swelling and burning extending to the anus

* TJpon pressing upon the umbilicus, a painful sensation is felt down to the anus, where there is constant pressing outward

Burning about the anus, so that he was scarcely able to sit

Burning and itching in the anus

Feeling of constriction, with, at times, stitches in the anus, on walking

* Dragging to the anus, as if diarrhoea woxdd easily ensue

* Pain in the anus, as if a plug were sticking in it, and forcing outward,™.

Sore pain, with burning in the anus, after moving about

Stool, followed by very painful sore sensation within the anus, with feeling as though the rectum was swollen and would protrude, with constant desire for another evacuation ; compression of the abdomen and pressure towards the intestines, causing pain extending into the genitals and ending in the glans penis as a sticking, so that, on account of the pain,, he became very anxious and oppressed, and was obliged to keep as quiet as possible; accompanied by sweat upon the forehead and nausea, with vanishing of sight and hearing; the pain was more violent when the body was bent over than when sitting, riding, or walking, which latter he was scarcely able to do on account of a very sore pain on the outer portion of the anus; the pain was gradually relieved by rest, when the anus seemed to return and become contracted ; this latter was followed by general prostration, ill-humor and loss of appetite

Scraping in the anus, immediately after a stool

Pulsating, sticking, and burning in the anus

Itching at the anus (after twelve hours)

Itching at the anus, obliging him to rub;10.

Urging, Urging to stool, in the morning, in bed ; on rising, a stool, rather soft, light-brown, followed by a very sore sensation in the anus

Urging to stool, with fulness in the abdomen and apparent fulness of the rectum ; the stool was scanty and difficult to pass

Urging and tenesmus while sitting at stool, with, however, passage of very little thin stool of a green-brown color, evacuated at three times and very forcibly as if shot out of the rectum

Great urging and pressing towards the rectum

Great urging to stool, the evacuation accompanied by griping, spasmodic pains in the abdomen ; stool rather soft, dark-brown, offensive

Immediate urging to stool on returning to the house

Sudden urging to stool ; he was unable to reach the closet, nevertheless was obliged to sit a long time

Frequent urging to stool without result (third clay ) ; the usual stool followed on the fourth day with some colic, succeeded by slight pains in the rectum

Constant urging to stool, followed by sudden pasty evacuation, which is shot out of the rectum, of a dirty-green color and offensive

Soon after luncheon, tenesmus and scanty evacuation, mixed with mucus (in five hours and a half)

Stool p. 616

Diarrhoea. Diarrhoea

Diarrhoea, with urging

Hypercatharsis (larger doses)

Free action of the bowels (repeatedly induced by putting two or three drops upon a surface denuded of its epidermis by a blister), (Rayer)

Violent purging, with great pain in bowels (after eight minutes), passages being without pain and apparently involuntary; the faeces had numerous streaks of a white, shiny, emulsion-like substance mixed with a large quantity of clear glairy fluid (after threequarters of an hour)

Recurrence of purging, after the first attack had been relieved (one case), (after eighteen hours)

Numerous evacuations, the first flocculent, the others yellow and green

Very frequent stools (two cases)

Twelve diarrhoeic stools, without colic (second day)

Bowels were opened freely (after one hour and a half), and at intervals for the ensuing thirty hours; in all, some thirteen movements

Stool at first nodular, mixed with many white points, the second containing many white long (3") worms as large as threads ; the remaining nine evacuations offensive and bilious, or slimy and at last watery

Ten copious, mucous stools, with some colic, but without tenesmus (after one hour)

Five stools, with profuse sweat, especially on the forehead

Five 'soft, slimy evacuations, without griping, with some tenesmus

Four forcible evacuations

Three watery stools (second day)

Acts upon bowels as a drastic purgative, causing three or four copious watery evacuations (1 or 2 drops), (after one or two hours)

Bowels very freely opened, twice (after one and two hours)

Two rather scanty diarrhoeic stools

Two dirty-yellow, mealy stools

The usual stool in the morning was followed by a second, after three hours

Solid stool (soon), followed by a liquid stool with slight borborygmi and slight colic, in the epigastric region and hypochondrium ; a third stool, also liquid (after two holirs and a half) ; a fourth stool (liquid), (after three hours aud a half) ; and a fifth stool also liquid (after six hours and a half )

* A pasty UghUrown stool covered with mucus, with frequent urging, followed by rumbling and gurgling in the text side oj the abdomen ; after another hour, a second, very soft, pasty, mucous, ana urgmt stool, of a grayish-green and dirty-brom color, which is evacuated forcibly

Soft stools, without tenesmus, and without heat in the anus

Watery stools, in the afternoon (second day)

Stools exceedingly large/ .

Profuse stool, with rumbling in the abdomen

Stool diarrhoea-like, light-yellow, accompanied by sweat, crawling in the occiput, pressure upon the larynx, especially the left side

Soft stool

Pasty stool, with burning in the anus?

A thin stool every day at the accustomed time, Thin stool, with scratching on the posterior left wall of the anus

Thin stool, with passage of flatus, in the afternoon ; in the evening, urging to stool reappears, but without result

* Stool very thin, like yellowish water, forcibly evacuated

Thin liquid stool, with passage of flatus (second morning)

* Watery, painless stool (after three hours and a half )

-Slimy stool, with tenesmus

Stool with some rumbling and colicky pains in the epigastric and hypochondriac regions

Stool at first fecal, afterwards watery, with slight sticking pain in the abdomen

Constipation. Constipation (second day)

Constipation followed after some days

Constipation (absence of the usual daily evacuations), and, at length, in seven hours, a scanty evacuation, caused by the efforts of the abdominal muscles, unaided by the peristaltic action of the bowels

The usual morning stool did not occur, but in the evening an unsatisfactory soft stool passed slowly and sluggishly (third day)

Stool crumbly, solid, passed with exertion

Stool tenacious

Urinary Organs p. 617

Urethra. Burning in the urethra, while urinating

Micturition caused burning in the urethra

Urging to urinate

Micturition. Frequent micturition

Micturition nearly every half hour

Increased secretion of urine

Increased secretion of urine, which was turbid and cloudy

Great increase of urine

Urine greatly increased in quantity

Passage of much yellow urine

Profuse secretion of urine

Profuse micturition, at least equal to the amount of drink

Urine. Urine pale, frothy

Urine pale, depositing a white sediment

Urine standing over night is pale orange-yellow, with a slight turbid sediment, which is at first somewhat flocculent

Urine which had stood through the night looked almost blood-red, and had deposited a thick mucous sediment

Urine, at night and in the morning, dark fiery red, depositing a very flocculent, turbid sediment, with some clearer substances; the surface covered with an oily pellicle

Foaming urine, in the morning

Turbid urine

Urine burning, soon becoming turbid, and depositing a copious brown sediment

The urine has a cloudy deposit, which, however, gradually disappears, and after twenty-four hours brownish crystals form, which seem to float where the clouds have been, and adhere to the walls of the glass

Sexual Organs p. 617

Male. The inner surface of the prepuce is slightly inflamed and irritable, with some secretion

Constant painful erections

No erection in the morning during the proving, contrary to custom

Burning in the glans penis, while urinating

Burning in the glans penis on urinating, immediately followed by renewed desire to urinate

Painful sensitiveness of the penis, with redness of the glans, and stitches in the urethra

Frequent corrosive itching on the glans penis and on the scrotum

* Scrotum shrivelled, with severe itching, especially disturbing the sleep; relieved by scratching, which, however, caused, a voluptuous sensation; this itching was troublesome for several daijs*1.--* Corrosive itching pain on the scrotum, lasting all day, worse while walking ; there was no eruption, only redness of the part (third day)

Left testicle retracted, the right relaxed

Drawing in the left spermatic cord hindering walking

Female. Menstruation, scanty (after fourteen days)

Respiratory Organs p. 618

Larynx, Trachea, and Bronchi. Laryngeal catarrh

Collection of mucus in the larynx, which rattles somewhat, in the evening

Accumulation of mucus in the larynx

Accumulation of mucus in the larynx, with tickling and irritation

Constant collection of mucus in the bronchials, which he is unable to remove

Frequent hawking, cough, and irritation to cough

Pressure in the larynx, especially the left side, with the stool

Provocation to cough, with accumulation of mucus in the trachea

Voice. Speech low

Voice hollow ; he is obliged to hawk constantly

Voice rather hollow than hoarse, as though he had a severe cold

Voice husky (second day)

Voice hoarse and rough

Coff/h and Expectoration. Cough in the evening, with white mucous expectoration and oppression of the chest

Cough with difficult yellowish expectoration; spitting of blood, after which the yellowish expectoration continued a long time

Frequent cough, in the morning, with expectoration

Constant cough

Expectoration of much tenacious mucus, which tastes sour

Respiration. Breathing short and hurried

Respiration slow and powerless

Respiration, 12,22.

Oppressed respiration

Respiration impeded and painful

Anxious, oppressed, difficult respiration

Respiration difficult, with constriction of the chest

* Sensation as though he could not get air enough into the air-cells, and could not perfectly expand the lungs

* 0n inspiration, it seems as though he could not expand the lungs

Difficult breathing

Very short breath after the stools

Respiration through the nose stopped

Dyspnoea, aggravated by going upstairs

Chest p. 618

Feeling of hollowness in the chest

Peculiar discomfort in the chest and abdomen

Peculiar malaise in the chest and abdomen, which forces him to yawn and stretch

Feeling as though there was mucus in the lungs, which could not be removed by hawking, together with difficult breathing, and slight whistling, on deep inspiration and expiration

Pains in the chest

Fulness of the chest, somewhat impeding respiration

Fulness, pressure, and burning in both thoracic cavities

* Feeling of fulness in both thoracic cavities, with burning stitches in the left thorax, and towards both scapiilce

Tightness at the chest

Pressure, deep within, at the. middle of the chest

Oppression of the chest

Oppression of the chest, in the evening

Oppression of the chest on deep inspiration

Oppression and an xietv

Severe oppression of the chest, in the evening

Stitches in the left thorax

Tearing alono- the edges of the ribs, extending backward and down to the small of the back 2

Painfulness of the chest to touch

Sudden throbbing in the region of the aorta,u.~ Front. Transient pressure over the sternum (after seven hours.

Sides. Pressive pain in the left chest, and left hVpochondrmm (after ten hours)

Pressive pain in the left chest, with feelinoof oppression (after twelve hours)

Sticking in the left half of the chest 14

Sticking in the right lower third of the chest, during inspiration 14

V olent stitches through the middle of the left side of the chest in the afternoon, Throbbing in the posterior portion of the right thoracic cavity, . F frequent throbbing-bubbling in the lower right side of the chest between the sixth and seventh ribs ; next day, very frequent throbbing and pulsating in the same region

Heart and Pulse p. 619

Frascordium. Very perceptible pulsation and throbbing of the heart

Sticking in the precordial region on expiration, repeated after one hour

Frequent sticking in the precordial region/*-

Some jerkings in the left side of the heart

Heart's Action. Palpitation of the heart in the afternoon

Palpitation after dinner, especially when lying down

Violent palpitation

Fulse. Accelerated pulse

Pulse rapid and weak (soon)

Pulse small and rapid (after three-quarters of an hour)

Pulse small, rather rapid

Frequent and weak pulse

Pulse so weak and quick that it could not be counted (after three hours)

Pulse 108, very feeble

Pulse 120 (after one hour and three-quarters)

Pulse 150, and very weak (after two hours and three-quarters)

Pulse small, weak, 64,™.

Pulse full

Feeble pulse (one case), (after eighteen hours)

Pulse weak and small;13.

Small, contracted pulse (after four hours)

Pulse at first weak and small, becoming stronger and fuller than usual

Neck and Back p. 619

Neck. Pain in the muscles of the left side of the nape, on nodding the head (after four hours)

Fulness extending up to the neck from the abdomen, with pressure in the pharynx

Pressure in the right side of the neck

Pressure and drawing in the cervical vertebra?,14.

Sticking between the nape and occiput

Back. Violent pains in the back and the lumbar region, in the space between the lumbar vertebra, false ribs, and ilium

Lumbar. Warmth starting from the lumbar vertebra

Pains in the small of the back

Violent sticking in the region of the left kidney, in the afternoon, • taking away the breath

Stitches in the left renal region (after four and a half hours)

Extremities in General p. 619

Trembling of the hands and feet

Weakness of the arms and legs (from the effluvia)

Pains in the limbs

Superior Extremities p. 619

Heaviness and weariness of both arms

Tearing in the right arm, extending to the upper arm, afterwards down to the fingers

Shoulder. Pressive pain in the right shoulder-joint

Sticking in the left shoulder-joint

Tearing in the right shoulder

Arms. Heaviness of the upper arm, which is easily fatigued

Heavytense sensation in both upper arms

Pain on the inner side of the left upper arm

A rheumatic pain in the left upper arm, waking him from sleep, disappearing during the day

Tension, weary pain, in both upper arms

Tension and pressure in the right upper arm, with sensation of weariness extending to the hand

Tearing in the right upper arm, and afterward in the right shoulder-joint

Sudden tearing pain in the left upper arm, especially in the deltoid muscle, lasting two hours (after four hours)

Elbow. Boring pain in the left elbow at noon

Forearm. Drawings in the right forearm

Tearing in the left forearm

Wrist. Drawing above the right wrist; in the evening

Fingers. Drawings and tearings in the left middle finger

Tearing pain in the finger-joints of the right hand, lasting several hours

Inferior Extremities p. 619

Weariness and exhaustion in the lower extremities

Prostrated and exhausted feeling in the legs

Hip. Tensive pain in the left hip-joint, which makes it difficult to rise from the Beat

Thigh. Paralyzed feeling in the left thigh

Awoke, after midnight, feeling as though the thighs were as heavy as lead

Burning and swelling of the nates where they approximate by the anus, after moving about

Itching burning in the middle of the left thigh

Especially painful pressure in the thighs

Sore pain between the left thigh and the scrotum (second day)

Knee. Tension and prickling in the knee-joints

Cramplike pain in the right knee-joint, transient (after ten minutes)

Drawings in both knees

(Drawing and tearing in the knee-joints)

Leg. Twitching of the legs during the midday nap

Pains in the legs and feet

Tearing in the left leg

Ankle. Heaviness and pressure in the ankles, in the evening

Sticking extending from the right external malleolus to the forepart of the foot

Foot. The feet failed him on going upstairs

Feeling of nervous weakness in the feet

Sticking on the margin of the left foot, as though she had turned , it, while sitting

Rheumatic tearings in the left foot

Frequent pain, as if sprained, in the left foot

Jerking in the left foot, while sitting,14.-

Frequent cramplike pain in the sole of the left foot, and on the inner side of the foot

Jerkings and tearings at times in the sole of the left foot

Toes. On walking he is attacked, three times in succession, with sticking and tearing pains as if sprained, especially in the left metatarsal bone of the great toe, so that he is unable to step fairly upon it

Violent sticking in the left great toe, and after a quarter of an hour also in the right

Rheumatic tearing in the right great toe

Painful prickling and sticking in the right great toe where the nail enters the skin

Crawling in the right little toe

Jerklike crawling in the right great toe

Generalities p. 620

Objective. Sudden emaciation

Trembling of whole body

Weakness

Great weakness

Great weakness on rising in the morning, with trembling of hands and feet

Very great debility

Prostration

Prostration of whole body, with frequent slight nausea

Stool followed by prostration, and some pain in abdomen

General prostration

State of collapse

During vomiting, and for two hours after, constant tendency to faint, and deathly, indescribable feeling of prostration (one case), (after eighteen hours)

Attacks of faintness

Lay in a lethargic state, sometimes drawing himself up as if in pain (after three hours)

Very restless; tossing convulsively about as if in pain (after one hour and three-quarters)

Generally lying quiet on belly, but occasionally tossing about (after two hours and threequarters )

Anxious oppressed tossing about in bed, with loss of sleep

Uneasiness

Subjective. Disinclination for every exertion

Weariness

Weariness, with prostration of the limbs, in the morning, on waking

General weariness and exhaustion, with ill-humor

Feeling of Weakness

Sensation of complete dulness of the whole body

General sick feeling

General sick feeling, worse after eating bread and butter ; she was obliged to lie down

Discomfort after dinner

Malaise, which is soon allayed; but a sort of nausea remains a long time after (in one hour)

Frequent stitches, with profuse sweat on the forehead

Tearings in left side, extending from groin up to right nipple, lasting several minutes

The pain causing nausea is aggravated while lying

Skin p. 620

Objective. Redness of the skin (from triturating the seeds in a mortar)

Slight redness of the skin, with a sensation of coldness, at last followed by slight warmth

Rubescence to a greater or less extent dependent upon the individual susceptibility ; this gradually increases until a general, though moderate, tumefaction occurs, apparently affecting parts deeper seated than I have seen occur from the use of any other external irritant ; this is succeeded, in a period varying from six to twelve hours, by numerous vesicles, some distinct, others confluent, differing in size and shape ; at first containing merely limpid serum, afterwards distinct and consistent pus, and terminating in slight scabs. The redness produced is not of a vivid, but of a dull brickdust hue. These circumstances, though regular in their course, vary in extent according to the parts upon which the oil is applied ; thus, on the abdomen, I have never been able to excite so active a rubescence as in other parts of the body. Over the muscular region of the arms and legs the effect is not so violent as where the bones are more superficially situated. The most powerful effects are produced upon the face, scalp, larynx, and chest, according to the observations I have made, in the order enumerated. When Croton oil is applied to the face and scalp it is frequently succeeded by erysipelas, but I have never seen any destructive or suppurating process established ; Whenever applied only erysipelas followed its use upon any part of the neck, abdomen, or extremities. In general, its effects are certain when applied to any part of the body, with the exception of over the abdominal muscles; at least I have never seen it tail of producing the sequelae described when applied upon any other part of the body

Enlargement of a cutaneous gland in the right lower lid, half an inch from the caruncula lachrymalis ; the skin is reddish and elevated, as large as a mustard-seed ; disappearing after four days

Ei'Uj>tions, Dry. Eruption of red pimples as large as millet-seeds, with corrosive itching and sore pain when touched or rubbed (from external application)

Erythema, with pustules (second day), forming crusts the next day

Eruption on the right side of the septum of the nostrils ; when washing in the morning the spot was painful to touch, was red, of the size of a pea; on the same day it formed a small slightly elevated crust, which desquamated on the sixth day ; the epidermis continued red and tender, and again desquamated

Burning-itching eruption round about the neck ; some pimples appear seated on a red base, and this when there could have been no direct application of the remedy to the face

Eruptions, Moist. ^Vesicular eruption on the scrotum and penis ( the patient's hands not having touched the parts), (from rubbing the oil upon the limbs)

Eruption of small vesicles on the labial commissures, right upper eyelid, and left buttock (caused by touching these parts when the hands Nvere covered with the ejecta), (second day)

Erysipelas phlyctenoides of the face, ending in desquamation in four hours (from an external application to the neclO

Several itching vesicles on the chin, which coalesce and form a scurf, which becomes moist on pressure • after about five days the crust desquamates and leaves a red spot which lasts a long time (after four days)

* On the left thigh opposite the scrotum, a red moist spot, exuding an offensive moisture; it is painfully sore to touch and walking, which also causes troublesome biting,™.

Eruptions, Pustular. The eruption which is brought out by the external use may be divided into five stages : 1. Rubefaction of the skin; 2. Formation of spicuous when the friction has been made with 10 or 12 drops of the oil on a part of the skin where there is much subjacent cellular tissue. The patient at first experiences a tingling warmth, which is quickly followed by a considerable redness, extending an inch or so beyond the sphere of the rubbing. These appearances are generally noticed within seven or eight hours, sometimes in one or two, at other times not for ten or twelve hours ; the differences of time required depending, no doubt, on the delicacy of the skin. In from fourteen to twenty-six hours myriads of small, close-set vesicles make their appearance upon the inflamed skin ; occasionally a few of the vesicles become greatly magnified, forming true phlyctenae, filled with a turbid lymph, which speedily changes into a purulent matter. In twelve out of thirt3r-one cases, reported by our author, the vesicles passed to desquamation without undergoing the suppurative process. The usual period at which the serum becomes puriform is from thirty-six to fifty-four hours after the application of the oil. In one or two days subsequently the pus begins to exude, and forms grayish crusts over the pustules, and the desquamation is generally over by the eighth or ninth day. If the Croton oil is rubbed upon any part which has been recently vesicated the eruption is, as we might expect, more speedy and abundant

A peculiar pustular and vesicular eruption (external application)

Papulopustulous eruption (second day)

The pustules are riper; their bases are inflamed ; some are larger than others, and have already lost the inflammatory areola, but are full and tense. There are large phlyctenae on the scrotum, and some pustules on the pubis; the glans penis is partly denuded of its epidermis (from the contact of the patient's hand covered with the oil). The urine is darker-colored ; urinating causes pain at the end of the penis, owing to the condition of the glans and prepuce (third day)

Not much smarting in the eruption ; there is some heat. A general redness in the affected part, which is covered with numerous white, glossy, tense pustules, having but slight areola?. Those which were in the same stage of development yesterday are now desiccated. Some small papulous vesicles have newly appeared ; others, with areola?, are just changing into true pustules (fourth day)

The pustules which desiccated yesterday have left only a yellowish spot or crust, formed of pus and dried epidermis ; those which were then at their height have sunken ; there are visible very small elevations, without areolae, remarkable for their regular shape, their small size, and the complete absence of surrounding redness; these are pustules developed between the laminae and the horny layer of the epidermis (intraepidermic pustules), (fifth day)

General redness diminished. The pustules are less numerous, and among them are some which are projecting sensitive, surrounded by areolae, and whose contents are of a reddish hue', owing to blood-globules mingled with the pus; these are dermic or sanguino-purulent pustules. A pustule was noticed surmounted by another smaller one. This is the heo-story pustule. There are some thick crusts caused by the patient's scratching open the pustules (sixth day)

Diminished eruption and redness; more crusts from torn pustules. An herpetic spot, which was situated at about the centre of the eruption, has almost disappeared (seventh day)

The evolution of the later pustules seems more speedy than on the first days, so that those which were fully matured yesterday have now hardly left a trace; even the raised epidermis has subsided. The two-story pudule, already observed, is developed - the top story, formed by an intra-epidermic pustule, has increased in size, probably from the effect of endosmosis; its circumference is no longer even with that of the lower pustule (eighth day)

All the pustules have sunken ; desquamation is beginning with the small pustules without areola? (ninth day)

Desquamation is proceeding; the herpetic spot appears again (tenth day)

Here and there new pustules, glossy and tense arrive at maturity, whilst others are desiccating; the herpetic spot has cleared off (eleventh day)

When the scabs fall off from the scratched pustules they are succeeded by pits, while they leave the others still elevated so that the hand perceives a roughness Long after the scabs have gone their places are marked bv a brownish discoloration, like the coppery hue ot syphilides (twelfth day)

The redness diminishes, and the desquamation continues to extend (fourteenth dav)

Formation of pustules aud almost general inflammation of the wafts of the abdomen, followed after several days by desquamation

Pustules thickly covering the whole scrotum and face ; the pustules on the side of the scrotum -were flattened and became suppurating ulcers ; in other parts the pustules dried and desquamated

The whole abdomen, even where the oil had not been applied, was covered with numerous small elevated pustules, surrounded with brighter areola, but without itching, and with no general symptoms (after two hours) ; violent itching began in the night, disturbing sleep and causing general discomfort ; on the next morning the redness was less marked, and every pustule had a tip somewhat paler than the skin around it ; pressure upon the eruption was not painful, but somewhat sensitive; gradually the pustules became pale, aud disappeared, without crusts or desquamation; on the eighth day only a few pale-red spots remained, not larger than a grain of corn

Slight redness, soon followed by burning ; on the next morning, while lying in bed on the left side, throbbing, tension, and frequent jerking in the left upper arm, extending to the fingers ; this spasmodic jerking involuntarily contracted the fingers; they noticed a large number of large and small, isolated, red-pointed, and roundish pustules ; the itching and burning were worse on touch or motion, especially on rubbing with the hand ; the arm and shoulder felt heavy; the whole skin was slightly red; the place felt rough and uneven ; the small pustules disappeared as whitish, shiny, small elevations; the whole skin became whitish; the large pustules remained red even after five days, when they gradually diminished, with only a very slight whitish desquamation, onl}' noticed when rubbing with the hand, when a few small scales were found upon the hairs of the arm ; an itching, which provoked scratching, remained for some two weeks, and also an alternating sensation of heaviness and tension in the upper arm

On the second day there was some itching in the place where the oil had been rubbed, but the surrounding skin, even where the oil had not touched, was still more red ; an eruption of very numerous, isolated, large and small, dark-red pustules ; movement of the arm causes some itching and burning; touch, or uncovering the part, even in the room, increased the painful burning and itching; the whole spot was elevated, uneven, and rough ; the small pustules disappeared after a few days, leaving a slight elevation of the skin ; the large ones remained for five days isolated and red

Herpetic eruption on the scrotum (from rubbing it into the abdomen)

Subjective. Itching after half an hour, followed by painful burning

Prickling in the lower third of the left lower leg

Prickling in the first toes of the right foot

Crawling in the lumbar region, as from beetles

Itching of the left upper lid

Itching on the right lower lid

Itching on the scrotum

Itching on the left middle finger, and on the right ring finger

Frequent itching, or rather smarting, as from vermin, in the pubic region, and on the glans penis (second day)

Very troublesome irritating itching on the scrotum (second day)

Prickling itching aud burning on the sole of the right foot

Corrosive itching on the scrotum, disturbing sleep, relieved by rubbing, which, however, caused erections (third day)

Corrosive itching on the scrotum, and a moist, offensive spot on the thigh ; these places afterwards become dry and desquamate

Sleep and Dreams p. 624

Sleepiness. Yawning, nearly the whole forenoon

Frequent yawning

Sleepiness

Sleepiness and prostration

Sleepiness towards noon, so that he wished to lie down ; after lying down after dinner inability to sleep, with some palpitation of the heart

Great somnolence and weakness (from the effluvia)

Almost irresistible desire to sleep

Easy falling asleep, followed by chill, especially across the back

Falling asleep from weariness, with numerous anxious dreams

-After the vomiting, fell into a deep sleep which lasted four hours

Sleeplessness. Sleep uneasy

Sleep uneasy, with many dreams

Sleep very uneasy and full of dreams

Sleep light, disturbed by many dreams

Sleep, with sudden waking, although he was unable to remember having a dream

Night restless ; full of dreams

Sleeps lying on the back, and sudden awaking after an emission

Dreams. Sleep very dreamy

Sleep disturbed by many dreams

Sleep, with heavy dreams, till 1 oclock at night, when she was suddenly awakened by violent headache

Night full of interrupted dreams ; he could not remember ever having passed such an anxious night before

Dreams about the occurrences of the day, during the afternoon nap

Fever p. 624

Chilliness. Surface cold

Surface of the body cool

Skin cool, clammy

Chilliness and shivering

Chilliness, especially in the abdomen

In the afternoon chilliness obliged him to seek his bed, where he did not get warm for a long time

Very transient attacks of chilliness extending especially over the whole of the back

Easily chilled.19

Coldness, especially of the lower extremities, so that she seemed covered with gooseflesh ; she was obliged to lie in bed in order to keep warm

Sensation of coldness, weakness, and prostration

Shivering all over (in three hours and a half )

Extremities cool

Extremities cold

* Coldness of the feet, extending as far up as the calves,1*. Feeling of coldness in the abdomen

Sudden coldness and paleness of the hands, with fingers very much shrivelled

Feet cold (after one hour and three-quarters)

* Feet and legs cold (after two hours and threequarters)

Extremities rather cold (after three-quarters of an hour ),60. Heat. Increased temperature of the whole body, followed by pricklingburning warm sensation

Warmth of body, especially of the face

Warmth over the whole body, followed by feeling of coldness in the reo-lou of the abdominal vertebrae

Warmth of the surface of the body, especially of the hands, which are usually cold, with remarkably swollen and prominent veins

Generally increased warmth of the whole body, with slight sweat

Skin, at first cool, becomes warm, and afterwards always profuse transpiration

Increased sensation of warmth through the whole body

Heat of the body

Heat and sensation of anxiety so that she sought for^a chair

Feeling of heat, with increased salivation

Flushes of heat

Hot and perspiring, with pulse as high as 190 (afterfive hours and a half)

Febrile symptoms

Feverish condition (with the eruption of pustules)

Creeping warmth in the parietes of the abdomen

Itching warmth in the upper third of the right tibia

Heat of the face, Slight febrile excitement across the whole upper abdomen .

Burning in the cheeks

Sweat, Sweat

Skin moist (one case), (after eighteen hours)

Sweat on the forehead

Sweat stood in drops on the forehead, and she thought she was unable to go to the house on account of the nausea

Conditions p. 625

Aggravation.

(Morning), Immediately on rising, contusion ot the head ; on waking, head heavy, etc.; after rising, pain in abdomen, etc. ; in bed, urging to stool ; cough; on rising, weakness, etc.; on waking weariness, etc.

(Forenoon), Pressure in stomach.

(Noon), Pains in head ; pain in elbow ; while sleeping, twitching of legs.

(Afternoon), Eructations ; stitches through left chest ; palpitation of heart ; sticking in kidney region ; chilliness.

(Evening), Lips dry, etc.; bilious eructations; sticking in spleen ; colic below navel ; passage of flatus ; colic ; mucus in larynx ; cough, etc. ; oppression of chest ; drawing above wrist; heaviness, etc.

(Midnight), Fulness, etc., at stomach.

(After midnight), On waking, heaviness in thighs.

(Open air), Confusion of head; vertigo, etc.; nausea, etc.

(Ascending stairs), Dyspnoea

(Beer with bread), Pains in forehead, etc.

(Bending body), Pain within anus.

(After bread and butter), Sick feeling.

(On coughing), Soreness in abdomen.

(After dinner), Pains in head; heartburn, etc.; griping; especially when lying down, palpitation; discomfort.

(While eating), Tearing in abdomen.

(After eating), Symptoms always aggravated; colic.

[During expiration), Scraping in throat; burning in fauces.

( Walking), Sticking in forehead ; pains in abdomen, etc. ; colic ; stitches in anus ; pains in great toe.

(During inspiration), Sticking in chest.

(Deep inspiration), Yams in walls of abdomen.

(Looking up), Vertigo.

(Lying), Pain causing nausea.

(After milk), Nausea, etc.

(After moving avoid), Pain in anus.

(On going out), Twinging, etc., in umbilicus.

(Pressure), Pains in walls of abdomen.

(On rising and while rising), Rumbling in intestines, etc.

(In room), Vision vanishes, etc

( While sitting), Desire to pass flatus ; tension, etc., of abdomen ; pains in upper abdomen ; sticking on margin of foot ; jerking in foot.

(Sitting xvith abdomen bent over), Pain in umbilical region.

(Before every stool), Griping in colon.

(After stool), Scraping in anus.

(Touch), Griping in intestines.

Amelioration p. 625

(Eating gruel), Pains in abdomen.

(Inspiration), Burning in fauces.

(Best), Pain in forehead; pain within anus.

Footnotes p. 620

† The prover was formerly subject to rheumatic troubles in the knee.