Guarana

Paullinia sorbilis. Mart.

Natural order, Sapindacejse. Common names, Guarana, Guarana-uva, Brazilian cocoa.

Preparation, Triturations of the seeds.

Authorities. 1, Montegazza ; general effects of ^ to 4 grammes ; Bull. Gen. de Therap., August 20th, 1867, from Annales d’Omodei, April, 1865; 2, Dr. W. Macdowell; J. D. G., aged 28 years, took ^ a drachm, first day; 1 drachm, twice, second day; 1 drachm, three times, third day; 3 drachms, fourth, fifth, sixth, and seventh days; 4 drachms, eighth day; Practitioner, Sept. 1873, p. 172; 3, J. G. took 1 ounce in drachm doses, ibid.; 4, Dr. Macdowell himself took 30 grains, twice, first day ; 30, 45, and 60 grains, second day ; 90 grains, twice, third day ; 90 grains, four times, fourth day ; then after two weeks’ interval, 1 drachm, first day; 3 drachms, second and third days ; 8 drachms, fourth and fifth days ; 1 drachm, three times, eighth day; 1 drachm, twice, ninth day ; 1 drachni, three times, tenth and eleventh days; 2 drachms, 4 times, twelfth day; ibid.

Mind

Gayety,h

Extravagant behavior

Mental hyper0esthesia ; intellectual excitement

He thought he was more lively and readier for work than usual

Unusual humor for continued hard work (second day)/.

Head p. 512

From 9 p.m. till bedtime my head felt rather confused ; I was quite “out of sorts and unable to settle to work (first day)

He awoke at midnight, and complained of a tightness across the forehead (second night); he fell asleep shortly, and had no return of pain in the head when he awoke next morning

Eyes p. 512

Persistent twitching of the eyelids (after first dose, second day)

Stomach p. 512

Loss of appetite

Bowels moved normally at 10.30 A.M., and a small motion occurred at 8 p.m. (fourth day); operated normally at 11.45 a.m. and 10.15 P.M. (fifth day)

Slight constipation

Very slight constipation (third day)

Bowels operated at noon ; decidedly constipated (second day)

Bowels operated at 11.45 p.m. for the first time for about seventy-two hours; a very unusual occurrence for me to be so very long constipated (third day)

Urinary Organs p. 512

Spasm of the bladder

Heart and Pulse p. 512

Diminution of the heart-beats

Before the proving the pulse averaged 70 in the morning ; 75 at midday and during the afternoon ; 78 at 9 p.m. ; 75 at midnight; during the proving, 73 during the morning; 70 at midday; 76 during the afternoon; 78 at night

Generalities p. 512

I felt unsettled, restless, and unable to work with vigor ; there was a really distressing fulness and throbbing in the head, chiefly in the temporal regions, afternoon and evening (second day)

Spasmodic restlessness

Shift p. 512

Urticaria

Prurigo

Sleep p. 512

Sleeplessness

(It prevented or removed drowsiness after food),".t

Fever p. 512

Temperature before the proving averaged 98.3° during the morning; 98° at midday; 98.1° during the afternoon, at 9 p.m., and 98° at midnight; during the proving, 98.3° during the morning ; 98.2° at midday ; 98.1° during the afternoon ; 98° at night