Indigo

An oxidation product, from the juices of several plants, chiefly Indigofera tinctoria, Linn.

Natural order, Leguminosae.

Preparation, Triturations.

Authorities. 1, Hartlaub and Tricks, Annales, 3, 329 ; 2, Blaufuss took repeated doses of 1 to 3 grains, Martin’s provings, Horn. Vierteljahrsschrift, 10, p. 81; 3, Fries took 1 grain daily for three days, ibid.; 4, Grsefe took 1 grain first day, 2 grains second day, ibid.; 5, Gunther took 1 grain daily for three days, afterward a dose of Tooth grain, ibid.; 6, Hilpert took 1 grain, first, second, and fourth days, proving subsequently repeated, ibid.; 7, Horn took 1 grain, first and second days, ibid.; 8, Kuntzrnann, proving with 1 grain doses, ibid.; 9, Martin, provings, 1 grain doses, ibid.; 9a, same, Tooth grain doses; 9 6, same, 5 grains of 1st trit.; 10, Oehler took Toffth grain in the morning and afternoon, ibid.; 11, Reichinann, effects of Tooth grain in the morning and afternoon, ibid.; 12, Vulpius took 1 grain, first, second, and third days, ibid.; 13, Werther took 1 grain daily for three days, ibid.; 14, Wilcher took 1 grain first and second days, ibid.; 15, Dr. Lembke’s provings, A. H. Z., 45, 338, repeated doses of 2d trit., 2 to 12 grains, afterward of 1st trit., 2 to 10 grains, and after a week 26 grains; 16, Both, Diss., Berlin, 1834, and Br. and For. Med. Rev., 1836, effects of Indigo in epileptics; 17, Dr. G. von Stahl, Jr. (reference as last), effects in epileptics; 18, Nankievitz, Preuss. Ver., 1837 (from Both, Mat. Med., I); 19, Hilsenberg, ibid.; 20, Groszheim, ibid., 1833 ; 21, Doepp, Hufel. Journ., vol. 80 (from ibid.); 22, Idler, effects of doses of from 1 scruple to 1 ounce in epileptic patients. Lancet, June, 1835, from Berl. Med. Zeit.; 23, same as 17; 24, same as 16.

Mind p. 93

Illusions of sensation; it constantly seems to her as though she had a large goitre, which was very prominent; she was constantly obliged to look down and feel whether it was so

Very lively mood (third day)

Sad, discontented, ill-humored, retired in himself

Great irritability (second day)

Ill-humor, in the evening (second day)

Fretfulness, ill-humor, indolence

Anxiety

Great anxiety

Great desire to work (fifth day)

Dulness of sense

Head p. 93

Vertigo. Vertigo (fourth day)

General Head. Rush of blood to the head (after 3 grains)

Congestion of the head, transient

Dulness and heaviness in the head on moving it, in the forenoon (after one hour),h

Heaviness in the head (twenty-second day)

Sensation of heaviness and swaying in the head (seventh day)

Head heavy and confused, with pressure deep within the brain (twenty-third day)

Head heavy, as if full, especially in the forehead, with increased warmth of the forepart of the head and drawing in the arms and legs, in the morning (second day)

Headache (second and fifth days)

Headache, with redness and heat of the face (first day)

Headache, in the evening (third day)

Headache, about 8 or 9 p.m. ; disappearing, but returning violently at 11 p.m. (second day)

Violent headache, with chilliness (second day)

Raging and beating in the whole head as with a hammer (after two and a half hours)

Warmth rushes into the head and distresses her for a long time as soon as she goes into the house after walking in the cold air; the grumbling also reappears frequently during the day, especially on suddenly rising from sitting or stooping, but disappears in the open air (first day)

Feeling of heat in the head

Heat in the head ; pressure in the temples from within outward (twenty-third day)

Transient heat mounts from the stomach into the head while sitting

Feeling of distension, and as if everything were turning around in the head, while reading at 8 a.m. (eleventh day)

A peculiar sensation of distension in the middle of the brain, with a trembling sensation on every step beneath both eyes and extending to the temples, with a painful, weak sensation in the lower legs (fourth day)

Bursting pressure deep within the brain extending towards the ears, at 8 A.M. (ninth day)

Dull headache, in the evening (second day)

Boring in the bones of the head in various places on the left side, several times (nineteenth day),'®. Drawing in the cranial bones (twenty-third day)

Drawing in the cranial bones and left side of the lower jaw (seventeenth day)

Pressure in the brain (tenth day)

Pressure in the cranial bones (twenty-third day),'^-y Pressure beneath the cranial bones, lasting a long time

Pressure within the head, in various places (nineteenth day)

Pressure deep within the head (fourteenth day)

Pressure deep within the brain (seventeenth and nineteenth days)

Pressure deep within the brain, as if upon the base of the brain, followed by a sensation of distension extending from the middle of the brain towards the temples (fifth day)

Tearing in the cranial bones, especially on the right side (eleventh day)

Tearing beneath the right cranial bones (twenty-fourth day)

Beating at times in the cranial bones; now in the right, now in the left side ; at times in the whole head while sitting, in the forenoon (third day)

Sensation in the head like a wavelike rushing, not unpleasant, almost itching; extending forward through the whole head to the forehead, whereupon the vision becomes indistinct; lasting a long time while sitting, in the forenoon

Forehead, Frontal headache (after a quarter of an hour)

Constant pain in the right side of the forehead (second day)

The forehead seems full and distended (nineteenth day)

Bursting pain in the forehead (seventh day)

Sensation as though the head were bound about the forehead with a band (after two hours and a half)

Pressure in the forehead (twenty-second day)

Pressure in the forehead extending to the sides of the head (fourth day)

Pressure in the right side of the frontal bone (fourth day)

Pressure in the left frontal bone (fifth day)

Frequent pressure in the forehead (eleventh day)

Violent pressure in the left frontal bone (third day)

Sticking in the middle of the forehead, just above the root of the nose (second day)

Tearing in the forehead and vertex, rather beneath the bones (nineteenth day)

Tearing in the forepart of the forehead, with sleepiness and prostration, in the evening (third day)

Tearing in the left side of the frontal bone (seventeenth day)

Bruised pain in the forehead (sixteenth day)

Temple, Headache, in the right temporal region, after the late breakfast (fourth day)

Intermitting boring as with a borer just in front of the left ear, in the temple

Drawing pain in the left temporal region (second day)

Pressure, or rather a cramplike pain, in the left temple (after one hour)

Pressure from within outward at the temples (fifth day)

Pressing from within outwards in the left temple (fourth day)

Pressure from within outward in the right, afterwards in the left temple (seventeenth day)

Sharp stitches in the right temple, in the forenoon (third day)

Some tearings in the right temple, and immediately afterwards in the chin and thumb, with gnawing in the middle of the lower jaw

Painful tearing and sticking in the left temple, deep in the brain; in the forenoon (third day)

Vertex. Sensation as though something heavy were lying upon the vertex (fourth day)

Heaviness in the head as if a heavy weight were lying on the vertex, when stooping, in the afternoon

Sticking in the top of the head, deep in the brain, and also externally (first day)

Acute though only transient sticking on the vertex, in the afternoon (third day)

Tearing on the vertex, deep in the brain, extending to the occiput

Pavietals. The head feels screwed in from both sides, relieved by stooping, less violent on rising up (seventh day)

Drawing in the right side of the head (after four hours),h

Pressure on the right parietal bone (third day)

Sticking pain in the right side of the head, extending thence to the ear (after one hour),h

Sticking as with knives in the right parietal bone and at the same time in the stomach, on sitting bent over, disappearing on becoming erect, in the afternoon (first day)

A coarse stitch in the right side of the head extending deep into the brain

Severe coarse stitches as with an awl in the left side of the head (after two days),h

Painful tearing in the right side of the head, extending forward, in the forenoon, while sitting (third day)

Beating externally in the left parietal bone; in the upper part near its union with the right; immediately a,afterwards a similar beating in the left outer ear, while sitting; after dinner

Violent jerking pain in the upper part of the right parietal bone, in the morning after rising; disappearing after some motion

Occiput, Painful raging in the bones of the left side of the occiput

Dull headache like a heaviuessin the occiput, in the forenoon

Warmth, and rushing like boiling water in the occiput (first day)

Heat in the occiput, afterwards more in the middle of the brain, lasting a longtime (fifth day)

Drawing pain in the left side of the occiput, in the afternoon

Pain in the left side of the occiput, lancinating, shooting through the head to the occiput (second day)

Extremely violent sticking pain in the right side of the occiput (after two hours)

Some violent fine stitches in the occiput, which reappear after a few minutes while sitting (first day)

Throbbing, together with painful stitches in the occiput, at 7 p.m. (first day)

Pulsation in the left side of the occiput, and in the right elbow-joint (first day)

Extemcil Head. Painful drawing in the upper part of the head, externally (after half an hour)

A peculiar sensation of fine sticking and of coldness in the scalp in front of and above the right ear, spreading out like rays from this point, quite momentary (first day)

Several fine burning stitches as when one pulls out a single hair (third day)

Feeling as if some one pulled a lock of hair on the vertex

Feeling as if some one pulled the hair on the left vertex, while sitting in the forenoon

Eyes p. 95

The eyes seem weak as though they would close, without sleepiness

Pressure in the eyes, for several days

Pressure in the left eye (after half an hour)

Ovhit, Pain in the left side of the orbit (after two hours)

Tearing in the bones of the left lower orbital margin, towards the nose, while sitting (after two hours and a half)

lads, Inflammation of the meibomian glands of the left lower lid (fifth day)

Jerking or twitching above the right lid, painless (first day)

Jerking and burning in the right lower lid

[HO.] Spasmodic twitching of the right lower lid (second day),*l

An agreeable sensation about the lids and nose (fourth day)

Sensation as if the upper lid were drawn down (after one hour and a half )

Twitching in the right canthus so violent that it impaired vision, in the evening (third day)

Fine sticking in the right inner canthus, disappearing on rubbing (second day)

Itching in the inner canthus, now in one, now in the other eye, in the evening (third day)

Eall. Pain in the left eyeball, in the evening (second day)

Ears p. 95

Sudden sensation as if the ears were stopped and as though the head were distended at both sides, immediately disappearing (third day)

Pain in the left ear, extending into the left parietal bone and left temple, while sitting soon after dinner

Boring gnawing pain in the left ear, extending towards the right, with undiminished mobility of the jaw, disappearing on rubbing, in the afternoon

Violent boring pain deep in the right ear, extending towards the parietal bone and over the temple, in the afternoon

Pressure and roaring in the ear (after one hour)

Painful sticking in the right ear, extending forward towards the temple; the pain extends into the right lower jaw (after half an hour)

Stitches in both ears at the same time (after one hour and a half ),h

Tearing deep in the right ear, shooting thence into the left parietal bone, in the forenoon (second day),h

Tearing in the right inner ear, then changing into the lower back teeth of the same side, while sitting in the afternoon

Painful tearing in the left external meatus, frequently repeated (first day)

Violent tearing in the right ear for half an hour, in the evening (third day)

Violent tearing in the right concha, in the evening (second day)

Violent tearing in the bone behind the left ear (third day)

Violent painful tearing in front of the right ear, in the bone (first day)

Roaring in the ears (fifth day)

Nose p. 96

Ohjective. Bleeding of the nose (thirteenth day)

Bleeding from the nose, in the morning (tenth day)

Bleeding from the right nostril, in cool weather and without apparent cause (fifth day)

Bleeding from the right nostril, in the evening during cool weather and without being previously heated (ninth day)

Nosebleed, with vanishing of vision, in the afternoon (third day)

The right nostril bleeds easily (second day)

Blowing of some blood from the right nostril, in the morning (second day)

Suddenly bright red blood from the right nostril, with a constricted sensation in the region of the heart and palpitation (eleventh day)

Ineffectual efforts to sneeze (after two hours)

Unusual sneezing (after a quarter of an hour’)

Frequent sneezing, especially violent at 11 P.M., often followed by great irritability of the nose (fourth day)

Violent sneezing, repeatedly, in the afternoon (fifth day)

Violent sneezing four times in quick succession, followed by some blood from the nose, which is bright red (fifth day)

Violent sneezing six or seven times (after half an hour)

Violent sneezing, lasting a quarter of an hour, followed by profuse bleeding of the nose, lasting three-quarters of an hour (after one hour)

Subjective. Stoppage of the nose (second to fourth day)

Drawing sensation extending up both nostrils (after one hour and a haff)

Tearing, cutting as with knives in the bones and cartilages of the nose, in the afternoon while sitting

Fine tearing in the right side of the nose, lasting a long time, in the afternoon (first day)

Great irritation in the root of the nose (fifth day)

Tickling in the nose (after two hours)

Face p. 96

Ohjective. Frequent rush of blood into the face, with burning in the cheeks (third Subjective. Tickling sensation in the face, in the evening (fifth day)

Cheeks. Sticking in the upper jaw and upper lip, in the afternoon (first day)

Pain in the right zygoma, extending to about the orbit

Very painful sticking as with an awl in the right zygoma; in the afternoon while sitting (fifth day)

Lips, Jerking in the right side of the lower lip, in the evening (third day)

Chin. Tearing in the chin (after half an hour)

Boring inhe right side of the lower jaw, especially beneath the back teeth (thirteenth day)

A boring pain in the angle of the left lower jaw, thence it extends up into the left temple and head, afterwards back again, while sitting- relieved by rubbing; after dinner

Boring-jerking pain extending from the right temple into the bone of the lower jaw, while sitting in the forenoon

Tearing in the middle of the right lower jaw, afterwards a similar pain in the teeth of the left upper jaw, while sitting in the afternoon,’._ Tearing in the right lower jaw, rather towards the front from time to time, while ^walk^ng in the open air, then also continuing in the house, lasting till evening (first day)

Violent tearing in the middle of the lower maxilla, which then changes to the back teeth, where it becomes a gnawing, while sitting in the forenoon,h

Boring, gnawing, tearing pain in the angle of the left lower jaw; thence it extends into the left parietal bone, then into the inner ear, afterwards in the right and then again into the left ear; together with throbbing deep in the bones; at 1 p.m. while sitting

Gnawing pain in the middle of the right lower maxilla, which then changes to the teeth corresponding to the same bone, disappearing when biting the teeth together; while sitting in the afternoon

Mouth p. 97

Teeth. Pain in the teeth, pressive (first day) ; intermitting (second day)

Toothache (fifth day); (fourteenth day)

Toothache, after dinner and supper (ninth day)

Toothache an hour after eating, lasting for two hours, and especially violent when walking rapidly (tenth day)

Fine, sudden, transient stitches in the upper incisors, nape of the neck, left ankle-joint (third day)

Tearing in the lower front incisors, and as she opens the mouth again two violent tearings, in the forenoon (first day)

Feeling of crawling in the roots of the three lower right front teeth, lasting an hour, transiently relieved by pressing upon them, at 7 p.m. (first day)

Crawling and almost tickling in the three front lower incisors, disappearing on biting upon them but immediately returning, at 4 P.M. (first day)

Pressive, frequent tearing pain in the right upper teeth, and especially in the left back teeth (after two hours)

Sticking in the roots of several upper teeth of the left side, at 2 p.m., especially violent about 4 p.m., and frequently repeated (seventh day)

Tearing in the right lower teeth (twelfth day)

Tearing and gnawing now in the right, now in the left lower molars, disappearing after lying down in the evening (third day)

Sudden tearing in the right lower hollow back teeth, as though the teeth would be drawn out; the tearing extends into the upper back teeth, the ascending rami of the jaw, the right ear, and the temples, associated with increase of saliva, perspiration of the right half of the head and general perspiration, in the evening in bed ; the pains are aggravated by warmth, relieved by motion of the body ; cold air seems to relieve for the moment; pulsation in the whole right side of the lower jaw ; (took Nux 3, at 10 p.m., after which the pain gradually disappeared) (sixth day); the pains in the right lower back teeth returned the next morning after the dose, were paroxysmal, afterwards increased, were aggravated by drawing in the warm air, and accompanied by accumulation of saliva; in the afternoon the teeth felt as if protruding from their sockets, returning at intervals for the next two days

Frequent jerklike tearing in the right lower back teeth, causing involuntary crying out, at 5 p.m. (eighth day)

Gnawing pain in three sound middle molars of the right upper jaw, which extends into the zygoma; thence the pain extends into the left middle upper teeth, and then into the corresponding zygoma, where it disappeared

Some jerks in the right lower back teeth (seventh day)

Tonfflie. Vesicle on the tip of the tongue, at 4 p.m.

Burning on the tip of the tongue, lasting a long time (after one hour)

Cooling burning, as from peppermint on the tongue in a small spot (after three hours)

Sensation of lateral contraction of the tongue, immediately

Biting on the tip and forepart of the tongue, as from pepper (soon)

General 3Ioutll. Burning in the posterior portion of the palate

Feeling as though there was a bad odor in the mouth, only noticed by himself (after one hour and a half)

Numbness of the whole inner mouth, in the morning after waking, disappearing after rising (second day),k

Silicum Profuse secretion of saliva (after one bour)

Expectoration of bloody saliva

Accumulation of water in tbe mouth (after two hours and a half)

Taste. Metallic taste on tbe tongue, soon after first administering, in most instances

Metallic taste on the tongue, with contracted feeling in the pharynx

The soup at noon seems sweet to her

Throat p. 98

Sticking in the left side of the throat while swallowing, in the morning (second day)

Tickling in the throat, with dry cough, during the epistaxis (third day)

Fauces and QSsophaffus. A sense of constriction at the fauces, soon after first administration (in most instances)

Distressing spasm at the isthmus faucium, when administered in the form of a powder (in some cases)

Scraping in the fauces, immediately

Feeling in the oesophagus almost like heartburn (after half an hour)

External Throat. Contractive sensation externally in the forepart of the throat (after one hour)

Cramp in the parotid glands (after one hour)

Drawing in the skin of the right side of the throat, extending into the lower jaw (after three hours)

Violent tearing, extending from the left submaxillary gland into the left lower teeth (after a quarter of an hour)

Jerking in the left jugular vein, disappearing for only a short time on rubbing, then returning again in a less degree, while sitting in the afternoon

Stomach p. 98

Appetite. Appetite increased (sixth day)

Increased sensation of hunger

No desire for anything at noon, though there was no aversion ; daily

Thirst. On the second, third, and fourth days, he drinks almost nothing

Constant inclination to eructate, with a distressing sensation in the stomach, lasting a long time

Friictation and Hiccough, Eructations and loss of appetite, towards noon

Frequent empty eructations

Ineffectual eructations (after two hours)

Sour eructations (after three hours)

Bitter eructations (after two hours)

Eructations tasting like ink, which she was unable to get out of her mouth for a long time (soon)

Sweet uprisings in the stomach

Hiccough

Hiccough after dinner (first day)

Nausea and Vomiting. Nausea, soon after breakfast (soon)

Nausea, after the early breakfast (second day)

Nausea, inclination to vomit, etc., with delicate persons even vomiting ; at times the retching is so violent as to preclude the further use of the remedy, whilst in other cases the nausea continues for two or three days, and then gradually subsides ; the retching and vomiting differ somewhat from those produced by common emetics, the contractions of the abdominal muscles and of the diaphragm being less violent, and the act not being succeeded by the usual feeling of distress and prostration ; the ejecta present no peculiarity, except a blue color

■ Nausea, vertigo, and headache, at noon (second day)

Nausea, with the headache and vertigo, lasting the whole afternoon, and only disappearinoin the evening, after being a long time in the open air (second da'y)

Nausea, with weakness (second day)

Nausea and eructations, with frequent inclination to vomit, without effect, and rumbling in the bowels (after two hours)

Great nausea, followed by vomiting, consisting of much mucus colored with indigo (second day)

Inclination to vomit (fourth day)

Frequent inclination to vomit, with eructations of a very great deal of gas

Vomiting

The vomiting takes place without much strain, suffering, or fatigue

At first the patient vomited freely, without any straining or derangement of the digestive organs **_ Vomiting, with diarrhoea

Vomiting of mucus

Women vomit more easily than men

Stomach, Gastrosis, with loss of appetite, pressure in the head, vertigo, and sometimes cloudiness of vision

Moving back and forth in the stomach, with burning (after one hour and a half)

Uncomfortable feeling in the stomach, with nausea and eructations of air, lasting a longtime (seventeenth day)

Cardialgia, with intestinal colic

Feeling of fasting in the stomach (after two hours)

Stomach feels as after complete fasting, with uprisings of heat from time to time, while sitting (after three hours)

Pressure in the stomach (soon); (first day)

Pressure and cutting pain in the stomach, as yesterday, after a cup of bouillon (fifth day)

Violent pressure in the stomach, aggravated by external pressure, with distension in the epigastric region (even while fasting) ; the pain lasted half an hour, and then extended to the back and into the left scapula, afterwards into the left arm ; a bruised sensation remained in the pit of the stomach ; a reminder of pain aggravated by external pressure (fifteenth day)

A clawing pain in the pit of the stomach, extending down into the umbilical region (first day)

Sudden cutting pain and pressure in the stomach, after a cup of bouillon ; the stomach does not seem to tolerate broth (fourth day)

Severe cutting pain in the stomach, with excessive flatulence, in the evening (second day)

Abdomen p. 99

Hypochotulcia. Pain in the left hypochondrium (seventeenth day)

Pressive pain in the right hypochondrium (after a quarter of an hour)

Painful stitch in the right hypochondriac region, as large as the palm of the hand, with a stitch extending to the front of the shoulder-joint; while sitting, disappearing on moving about

JJmhilical. Intermitting gurgling extending from the stomach into the abdomen in the umbilical region, while sitting (after two hours)

Pain in the umbilical region; (fifth day)

Pain in the umbilical region, which feels hard to the touch, aggravated by pressure and inspiration, as well as by fasting, and also in the evening, only, however, while sitting (first day)

Violent cutting pains at the umbilicus (second day)

Griping about the umbilicus and urging to stool, followed by diarrhoea, with griping in the abdomen ; after the stool the griping ceases (after one hour)

General AJbdomen. Rumbling and moving about in the abdomen

Flatulence (soon),”; (after half an hour)

Emission of much flatulence (second day)

Unusual flatulence and urging to stool (after one hour, second day)

Frequent emission of offensive flatus, in the evening, night, and morning (second and third days)

Slight gastro-enteric pains during nausea and retching, and during the diarrhoea, in rare instances so violent as to proscribe the further use of the remedy

Pain in the upper abdomen, with nausea and anxiety, lasting an hour, at 2 a.m. (first day)

Painful tension about the upper abdomen; afterwards griping, followed by at first hard then liquid stool, in the afternoon (first day)

Fulness in the abdomen, with much flatulence (second day)

Sensation of fulness and moving of flatulence in the abdomen

Griping and rumbling in the abdomen, as if diarrhoea would follow; afterwards a soft stool, with emission of much flatus (fourth day)

Violent griping in the whole abdomen, about 5 a.m., so that she is awakened by the pain, followed by urging to stool, and a profuse semiliquid stool, with cessation of the pain

Uncomfortable, oppressed sensation in the upper abdomen, on waking unusually early in the morning (second day)

Cutting pains wandering about the whole abdomen, aggravated by pressure, worse in the rectum (twenty-second day)

Constant cutting pain in the abdomen, increased by retracting the walls of the abdomen and by pressure, momentarily relieved by bolding oneself erect; the abdomen is full of gas (the pains last two hours'), (third day)

Violent colic, with flatulence and urging to stool (third day)

Twinging in the abdomen in the morning in bed, followed by the usual stool and cessation of the pain (third day)

Hypogastiiiim and Iliac Megion. Griping in the right lower abdomen, lasting a minute, at 7 p.m., soon followed by a soft stool and disappearance of the pain

Pain almost like a drawing in the right groin near the ilium, immediately afterwards a griping in it, and afterwards a stitch from within outward above the female breast

Pinching-sticking cutting, or rather a long stitch, as with a knife in the right groin (after second day)

Violent stitch in the left groin, so that she was obliged to stand still ■while walking, at 1 p.m. (second day)

Twinging in the left groin, extending to beneath the ribs, while sitting, after dinner

Biting in the left groin (after one hour and a half)

Rectum and Anus p. 100

Dull sticking in the rectum (twenty-third day)

Urging to stool, followed by liquid evacuation (after half an hour)

Great urging to stool, at 6 p.m. (second day)

Stool p. 100

IJiavrlicea. It seems to promote the stool in its primary action

Slight diarrhoea, which, however, ceases spontaneously when the Indigo begins to be more easily assimilated with the digestive organs

Constant diarrhoea

After all inclination to vomit has ceased a diarrhoea usually takes its place, increases rather than diminishes as the treatment proceeds, and lasts during the whole time that the Indigo is administered ; from four to six stools of a semifluid consistency and a blue-black color are produced daily, with accompaniment of slight gastro-enteric pains

At first the patients vomited frequently, without any straining or derangement of the digestive organs; after a few days this ceased, and they had six or eight stools a day, sometimes accompanied by slight colicky pains ; after a short time the purging diminished, the matter passed assumed a fluid character, and this state continued as long as the drug was administered, without the appetite or digestive organs being injured

Four to six soft stools daily

Two evacuations in the morning, followed by tenesmus, without pain in the abdomen (after second day)

Stool with violent pressure, though it was soft, and after a quarter of an hour a loose stool

Liquid stool, without any symptoms either before or after'

Urging to stool, followed by liquid evacuation (although he had had a stool shortly before taking the drug), soon

Stool softer than usual (fourth day)

Hard stool daily

Constipation. Bowels remained obstinately constipated instead of being relaxed (one or two cases)

Stool indolent during the whole proving

Stool delayed, scanty, hard, for several days (ninth day)

Stool withheld (first day)

Stool retained (second and third days)

Urinary Organs p. 100

Bladder, Pain in the bladder, during micturition (second day)

Urethra. Sticking iu the urethra (fourth day)

Peculiar itching in the urethra and on the scrotum (second day),®._ M-micturition, Constant desire to urinate; the urine is turbid (second day)

Constant desire to urinate, he is obliged to go every hour regularly, without, however, having drunk more than two cups of coffee; urine turbid (second and third day)

Secretion of urine decidedly increased, so that he was obliged to pass it twenty-four times during the day ; however he had respite during the night; during micturition a decided sensation of contraction of the urethra, with pain in the region of the bladder • urine very slimy and turbid (fourth day); symptoms somewhat relieved, urine much clearer and passed with less tension (fifth day),h

Great desire to urinate, at an unusual time (first day)

Great desire to urinate (after one hour) ; urinating four or five times during the hour

Frequent urging to urinate with burning in the base of the bladder (after fourteen days)

Excessive and frequent urging to urinate in the afternoon, and especially at night; only a little turbid urine was passed each time, and micturition was painful (first day)

Frequent micturition, with pressure in the abdomen, urine clear, throughout the first day

Increased emission of urine

Increased flow of urine, in the afternoon (second day)

Burning micturition (third day)

Urhie, Urine increased (third and fourth day)

Urine increased and passed more frequently than usual (second day)

Secretion of urine increased (second day); in afternoon

Urine of a dark violet hue; that secreted at night paler than that of the morning

Urine colorless, very thin (first day)

Urine turbid (second day)

Sexual Organs p. 101

3Pale, Coldness of the glans penis and prepuce

Itching of the glans penis (fourth day)

Sexual excitement increased (fourteenth day)

Sexual desire somewhat increased (fifth day)

Sexual desire greatly depressed (third day)

Female. Menstruation eight days too early (sixth day)

Respiratory Organs p. 101

Larynx and Trachea. Sticking in the larynx, in the evening (third day)

Sticking and tickling in the larynx, with irritation to cough (first day)

Fine sticking in the larynx, lasting a long time (first day)

Stitches in the larynx and short paroxysms of cough, a few times (fifth day)

Violent stitches in the larynx causing lachrymation and accumulation of saliva (sixth day)

Clawing pain in the trachea, which gradually extended lower down until it seemed to involve the smallest bronchi, provoking cough which loosened small masses of tenacious mucus; these symptoms gradually disappeared after half an hour (after half an hour)

Cough and Expectoration. Cough in the morning after rising, soon disappearing

Cough wakes her frequently at night; she also coughs frequently during the day (sixth day)

Cough amounting to suffocation, in the evening before, and two hours after, lying down (second day)

Violent cough, which provoked vomiting, before, and half an hour after, lying down (third evening)

Profuse expectoration of mucus from the bronchial tubes and trachea

Respiration. Oppressed respiration, while sitting (fourth day)

Respiration impeded, like a cramp in the chest, in the open air (after ten minutes, first day)

Difficult respiration

Difficult respiration, with oppression of the chest as from a weight, worse while sitting, lasting several hours (twenty-second day)

Respiration short and difficult, with oppression of the chest and anxious sensation in the heart and short beats of the heart, worse during rest, better when walking (lasting several hours), (twenty-third and subsequent days)

Chest p. 101

Rumbling and gurgling in the chest on every inspiration, lasting a long time

Pain in the walls of the chest, in various places (thirteenth day)

Pain in the short ribs of the right side (after two hours)

Pain almost like a burning in one of the lower ribs of the right side, frequently occurring (first day)

Tightness in the chest (twenty-fourth day)

Tightness of the chest, with difficult respiration (seventeenth day)

Pressure on the middle of the chest, without affecting respiration (after one hour and a half)

Pressure upon the chest and oppression behind the sternum (fifth day)

Pressure upon the chest, with difficult respiration (seventh day) ; while sitting (first day),'^. Oppression of the chest

Oppression of the chest, the breath is inspired with difficulty, while sitting (third day)

Oppression of the chest with palpitation, while sitting (fourteenth day)

Constant feeling of oppression in the chest as from a weight, with difficult respiration, and with the assistance of the abdominal muscles, while sitting (nineteenth day)

Cutting pain in the middle of the lower false ribs of the right side, in the forenoon (first day)

Sticking in the walls of the thorax (eleventh day)

Stitch in the right false ribs, extending to the small of the back (after two hours),’. Stitches extending around the left wall of the thorax (second day)

Sharp stitches in the lower false ribs, very painful

Fine stitches through the left lung, more towards the anterior wall of the thorax (fourth day)

Constrictive stitches in the chest

Violent palpitation, like a twitching, in the region of the right fourth and fifth ribs, at 3 p.m. (second day)

Front. Pain in the sternum and on the sides of it (sixth day)

Gurgling-like pressure in the upper part of the sternum (after two hours)

Pain in the sternum as if bruised, on entering a warm room

Pain almost like a sticking in the ensiform cartilage

Pain like a cutting above the ensiform cartilage (first day)

Sticking in the sternum, in the afternoon, while sitting (second day)

Stitches behind the sternum (first day)

Violent sharp stitch in the middle of the sternum, extending through the chest, while sitting (after two hours and a half)

Three sudden frightening stitches in the sternum, above the pit of the stomach, in the forenoon (first day)

Sides. Pain in the right wall of the thorax, after supper (fourth day)

Drawing pressure in the side of the chest, just beneath the axilla, extending through into the right scapula, in the afternoon while sitting

Sticking in the right side of the chest near the sternum (after one hour)

Fine stitches in the left wall of the thorax (third day)

Tearing in the left wall of the chest (twenty-fourth day)

Throbbing in the right side of the chest (fourth day)

3T(ininiW. A long-continued burning behind the left breast while sitting (third day)

Boring into the right female breast while sitting

Painful sticking in the left female breast; on rubbing it extended farther backward; afterward it appeared again in the first place, while sitting in the afternoon,’.-

Extremely painful stitch beneath the left female breast, extending inward, in the afternoon while sitting

A long stitch just beneath the right nipple (after three hours)

A sudden burning stitch near the left female breast, near the sternum, extending inward, in the afternoon while sitting

Heart and Pulse p. 102

Prcecordium. Tensive pain in the region of the heart (third day)

Oppression at the heart, while sitting (fourth day)

Hearths fiction. Some violent beats of the heart at its tip (seventh day)

Several strong beats of the heart (sixth day)

Violent beating of the heart (eleventh day)

Violent beating of the heart perceptible in the head, at 7 a.m. (seventeenth day)

Violent irregular beating of the heart, while sitting

Palpitation (two hours after 3 grains)

Palpitation with oppression of the chest (eighteenth day)

Palpitation and rush of blood to the head with heat, while walking rapidly, even lasting some time in the house, in the evening (fourth day)

Pulse, Pulse rapid (second day)

Pulse more rapid than usual, with violent beating of the heart perceptible in the head and arm, together with short and impeded respiration, while sitting (frequently repeated during the day), (seventeenth day)

Pulse spasmodic; (after half an hour)

Hard pulse (two hours after 3 grains')

Neck and Back p. 103

Week, Feeling of stiffness in the cervical muscles, during rest (fourth day)

Drawing in the left side of the neck (eighth day)

Violent drawing on the left side of the neck, while walking, especially under the skin (seventh day)

Violent pressure in the muscles between the neck and left shoulder, several times (sixth day)

Tearing beneath the skin on both sides of the neck, in the evening (fourteenth day)

Tearing in the left side of the neck (twelfth day)

Tearing extending up and down in the left cervical muscles (third day)

Hack. Drawing extending from the small of the back into the shoulders (after three hours)

Sticking in various muscles of the back (seventeenth day)

Bruised pain in the muscles of the back (twenty-third day)

Dorsal. Pains in the left scapula (fourth day)

Pressure between the scapulae

Dull pressure in the spinal processes of some of the dorsal vertebrae, lasting a long time (fifth day)

Constant fine sticking in the right scapula (after one hour)

Drawing sticking pains following the course of the left musculus rhomboideus

A stitch between the sea[)ul?e, after dinner

Stitches in the scapulae (nineteenth day)

Stitches in the muscles between the scapulae (first day)

Lulilbav. Sticking in the small of the back, preceding a hard stool; the pain disappears after the stool (first day)

Dull stitches in the right lumbar region, intermitting

Nephritic colic, with greenish urine

Extremities in General p. 103

Objective. Subsultus tendinum in all the limbs (third day)

Weariness of the limbs (fifth day)

Weakness of the hands and feet, as if sprained (third day)

Subjective. Feeling of weakness in the limbs (fourth day)

Drawing in several joints (tenth day)

Pressure in the right elbow (fifteenth day)

Pressure in right lower leg and right forearm (sixth day)

Pressure in left calf and forearm

Pressure in left calf, upon right tibia, and right radius, coming and going several times (fourth day)

Tearing in right shoulderjoint, afterwards in right ankle (fourteenth day)

Tearing in the joints of the hands and feet, a few times during the day (third day)

Tearing in the right great toe and in the first and middle joints of the left ring and middle fingers, while sitting in the afternoon

Bruised pain, suddenly changing its location, in the joints and soft parts near the joints (nineteenth day)

The pains in the limbs seem to be aggravated after every meal (sixth day)

Superior Extremities p. 103

Weakness of the arms, in the forenoon

Drawing in the muscles of the arms (eighteenth day)

Drawing, extending down the left arm, starting from the lower portion of the neck (fifth day)

Drawing, extending from the right shoulder-joint through the whole arm as far as below the joint of the thumb, where it ended in the bone \with a jerking, while sitting; disappearing on moving about (after three hours)

Frequent bruised pain in the arms (sixteenth day)

Shoulder. Pressive pain in the right deltoid muscle (twentysecond day)

Sticking beneath the right axilla

Sticking pain through the left shoulder from before backwards, while sitting in the afternoon

Violent sticking in the right shoulder-joint, at 4 p.m.

Tearing in the left shoulder-joint, at 4 p.m. while sitting

Upper Arm. Pain beneath the left humerus (after two hours)

Drawing in the right upper arm (seventeenth day)

Painful jerking drawing, extending from the right shoulder along the outer surface of the humerus to the vicinity of the elbow and back again, thence into the right scapula, where it disappeared, while sitting,h

Sticking on the outer surface of the right upper arm from without inward (after two hours)

Frequent stitches in the upper arm (seventh day)

Tearing in the right upper arm (twelfth day)/

Tearing in the left upper arm (fourteenth day)

Tearing in the muscles of the right upper arm (eighth day)

Tearing in the middle of the right upper arm, in the bone, at first aggravated by pressing upon it, but relieved by long-continued pressure, while sitting (first day),h

Tearing and pressure in the muscles of the upper arm, frequently followed by a sensation of loss of power in the forearm, which is afterwards felt in the pectoral muscles (twenty-second day)

Painful tearing above the elbow, extending into the shoulder-joint, while sitting in the afternoon

Bruised sensation in the left upper arm (twenty-third day)

Bruised pain in the left upper arm (sixth and seventeenth days)

Bruised pain in the right upper arm, afterwards on the inner margin of the left scapula (fifteenth day)

JElboiV. Sticking in the elbow-joint, extending into the shoulder, while sitting in the afternoon

Fine sticking just above the bend of the right elbow, at pulselike intervals (after two days)

Two burning stitches in the right inner condyle of the elbow

Fine tearing in the anterior surface of the right elbow, as if in the periosteum, disappearing after pressing upon it

Gnawing pain in the elbow-joint, extending along the ulna to near the wrist, relieved by moving and flexing the arm (after two hours)

Violent pulsation in the left elbow-joint (fourth day)

Foveuvm. Rheumatic pains in the forearm

Drawing in the right radius (fifth day)

Drawing in the muscles of the left forearm, afterwards in the right (eleventh day)

Drawing pain in the left forearm at the place where one feels the pulse (after half an hour)

Violent gnawing-tearing pain, extending from the elbow-joint down the posterior side of the arm as far as the first joint of the right little finger; after moving the arm the pain again extended into the elbow, thence into the shoulder-joint; after violent motion it again returned in the same finger-joint, where it at last disappeared, while sitting in the forenoon

Wf ist. Sticking in the right wrist on moving it, lasting five minutes (second day)

Uufld, The veins of the hands swell, become red, and tense, as if swollen, in the forenoon (second day)

Transient sticking on the back of the right hand in the first finger-joints (second day)

Tearing in the back of the left hand (after half an hour)

Tearing in the metacarpal bone of the left thumb (seventeenth day)

Fhufers, Pain in the left index finger (after tw’o hours)

Drawing in the left thumb and in the lumbar muscles; disappearing on moving about (third day)

Drawing in the left fingers, in the upper arm, and in the right side of the forehead (eighth day)

Pressure in the joints of the right thumb

Fine stitches on the dorsal surface of the second joint of the left index finger, worse on moving the joint (seventh day)

Painful tearing in the first phalanx of the right thumb, and a painful drawing from the left shoulder into the left side of the head (after two hours and a half)

Jerking tearing in the »’'<rht little finger, especially in the last and middle joints, while sitting in the afternoon

Inferior Extremities p. 104

Great weakness of the lower limbs, even in the evening, lasting after lying down (sixth day)

(Rheumatic heaviness of the limbs), (second day)

A drawing in the anterior surface of both legs, while walking, changing to a sensation of weakness while sitting (fourth day),^^-

* Tearing pain four fingers breadth above the the left kneejoint, extending to a hand’s breadth above the ankle; in the afternoon while sitting; disappearing 07i rising and walking about

Hip. Sticking from without inward just above the right hip (after two hours)

Thigh. Indescribable pain, extending from the middle of the thigh to the knee, in the bone, disappearing when walking and returning during rest, in the afternoon

Drawing in the flesh on the outer side of the right thigh (first day)

Tearing in the left femur towards the outer surface, while sitting after dinner

Tearing in the middle of the left thigh, in the bone, in the afternoon while sitting (third day),b

Bruised pain in the middle of the thigh, as usual before the menses, even while in bed in the evening (fifth day),b

Wandering bruised pain in the left thigh, back of the right foot, and right side of the cranial bones (twenty-second day)

Knee, Constant weariness of the right knee (first day)

Boring pain in the left knee-joint, while sitting

Drawings in the left knee and in the left dorsal muscles (fourth day)

Drawing pains in the left knee-joint, extending to the middle of the left thigh, in the bone (after three hours),b

Pressure above the right knee (seventeenth day),’b

Stitches in the right knee (sixth day),’b

Stitches in the forepart of the knee, while sitting (second day),^b

Tearing in the knee (after three hours),b

Leg, Pain, extending from the knee-joint through the tibia to below its middle, while sitting, disappearing on moving about (after two hours),b

Drawing in the left lower leg (ninth day),^b

Drawing in the left tibia (twenty-second and subsequent days)

Painful drawing on the outer side of the left leg, remaining for some time in the external malleolus and its vicinity (first day),^b

Pressure in the lower legs (fifth day),^b

Pressure in the left leg (twenty-third day)

Pressure in the left calf and in the right wall of the thorax (fourth day),'b

Pressure in the left calf, continuing as long as he keeps the leg quiet, but disappearing on moving it (first day),^b

Pressure in the right tibia (second day),^b

Dull pressure in the left tibia, extending into the ankle-bone (second day),^b

Sticking in the left calf (seventeenth day)

Tearing in the right lower leg (seventh day),^b

Tearing from the left ankle to above the knee, in the bone, in the afternoon,b

Tearing in the right tibia (nineteenth day),^b

Tearing in the left tibia (seventeenth and eighteenth days),*b

Pricking sensation in the left leg, at the point where the muscle passes into the tendo Achillis, in the afternoon

Bruised pain in the joints and muscles of the right leg (nineteenth day),^b

Anhle. Heaviness in the malleoli of the right ankle, with a feeling of contraction extending up into the thigh (after two hours),b

Violent drawing in the right ankle, in the left radius, afterwards in the right (eleventh day),^b

Pressure in the right ankle and right parietal bone, after dinner (fourth day),’b

Pressing in both ankles, compelling him to move them, when it disappears (first day),^b

Much fine sticking near the right inner malleolus (first day),^b

Stitches in the left ankle (seventeenth day),*b

Continuing stitches in the right internal malleolus, while in bed in the evening (third day),^b

Foot. Feeling of weakness of the left foot,b

Drawing upon the back of the left foot, afterwards on the right (fifth day),^b

(Suddenly the most violent pain in the sole of the left foot, in the forenoon while sitting, she was unable to step upon it, with a feeling as if the tendons were too short; she was obliged to limp while walking; the ball of the foot was thereby swollen; when the foot hangs down, and also at night, there is a throbbing, long-continued, as in an abscess, even painful to pressure, lasting eight days),ht

Drawing in the left heel and ankle, while sitting (nineteenth day)

Toes, Drawing in the right toes and right side of the forehead (seventh day)

Two violent painful tearings in the joints of the left great toe, so that she fears that the toe will be torn from the joint, while sitting during dinner

Generalities p. 106

Objective, Circulation excited

Nerves very much affected (sixth day)

Subsultus tendinum

Slight ^spasms and twitchings of the tendons (after a few weeks), (in some cases),'**. Indolent, very weary, in the forenoon

Unusually little weariness, after eating

Great weakness through the day

Great weakness, after only a short walk

Subjective. Constant malaise and vomiting

Very sick and weary (second and third days)

Sticking and tearing here and there over the whole body, in the afternoon and evening (fifth day)

The pains are either removed entirely by rubbing and pressure, or they return in a less degree

Skin p. 106

JEruj)tions Dry, Eruption of fine heat-rash, especially on the leftside of the face, extending from the forehead to the throat (after 3 grains)

Pimples on the forehead, also on the right side of the lower jaw, all with a painful sensation (fifth day)

The whole face and also the whole body covered with pimples (after a few days)

Eruptions 3Ioist. Itching vesicle on the back of the left hand, in the evening (third day) ; the following morning the same on the back of the right hand

Eruptions Pustular. A small boil on the right side of the neck, disappearing after three days (after seven days)

A rather large boil on the left nates (after four days)

Subjective. Itching of the skin, especially of the face (after 3 grains)

Violent itching in various parts of the body, especially in the right elbow-joint (second day)

Tingling in the forehead (fifth day)

Tickling sensation alternately in various parts of the face, especially about the external canthus and wing of the nose (third day)

Feeling of tickling in the left cheek (second day)

Itching on the chin, disappearing on rubbing

Itching of the hypogastric region (third day)

Itching of all the limbs

Itching on the backs of both hands, followed by eruption of hives, which soon disappears, but returns in the evening (after one hour)

Itching on the back of the left hand, with eruption of two pimples

Itching on the inner side of the thigh (third day

Sleep and Dreams p. 106

Sleepiness. Yawning, with sleepiness (after two hours)

Much yawning

Frequent yawning, in the forenoon

Great inclination to sleep, the whole day (third day)

Sleepiness in the afternoon

Great sleepiness in the evening (first day)

Great sleepiness, while sitting, at 9 a.m.

Excessive sleepiness (third day)

Very sleepy towards evening, but then a restless night (second day)

Prolonged sleep, in the morning, with agreeable dreams of journeyings (third day)

Sleeplessness, Falls asleep late in the evening

Sleep gentle, refreshing, but not sound

Uneasiness at night

Starting up and frequent waking at night

Dreams, Uneasy dreams at night (second day)

Frightful dreams (fifth day); (sixth day)

Remembered dreams of quarrels and fights (first night)

Dream of flying upon the back, several feet above the earth (first day)

Anxious dream that she was riding in a wagon, and the horses ran away, whereupon she woke in a fright (second night)

Muttering unintelligible words in sleep, before midnight (first day)

■}• She had a similar attack four months previous, after a long walk.

Fever p. 107

ChiJlittess. Chilliness over the whole body (after half an hour); (second day),^l

Chilliness of the whole skin, coldness of the usually warm hands (after one hour)

Unusual chilliness (the whole first day),k

Coldness in the morning, after rising

Some coldness befoi’e going to sleep,b

Coldness of the hands, lasting a quarter of an hour (after half an hour)

Heat. Great heat, especially of the face

Feeling of warmth in the forepart of the chest (first day)

Conditions p. 107

Aggravation.

(Morning), Head heavy, etc.; at 8 oclock, while reading, feeling in head; after rising, pain in parietal bone; after waking, numbness of inner mouth ; early, on waking, sensation in upper abdomen; after rising, cough ; after rising, coldness.

(Forenoon), While sitting, beating in cranial bones; while sitting, sensation in head; stitches in temple ; tearing, etc., in temple; while sitting, tearing in side of head.

(Afternoon), Sticking on vertex ; while sitting, sticking in zygoma ; at about 4 oclock, sticking in roots of teeth ; at 5 oclock, tearing in back teeth ; while sitting, sticking in sternum ; while sitting, j9ams in limbs; sticking, etc., all over.

(Evening), Headache; at 8 or 9 oclock, returning at 11 oclock, headache ; twitching in canthus ; itching in canthus; pain in eyeball; pain in stomach, etc.; sticking in larynx ; cough ; palpitation, etc.; tearing in sides of neck; stitches in malleolus; sticking, etc., all over.

(Sitting bent over). Sticking in parietal bone, etc.

(After breakfast). Nausea.

(After walking in cold air). On going into house, warmth rushes into head.

(After dinner). While sitting, relieved by rubbing, pain in angle of jaw; hiccough.

(After eating). The pains; especially when walking rapidly, toothache.

(Fasting), Pain in umbilical region.

(Inspiration), Pain in umbilical region.

(After every meal). Pains in limbs.

(Motion),Th.e, pains.

(Pressure), Pain in umbilical region.

(Rest), All symptoms.

( While sitting). Heat from stomach into head; stitch in hypochondriac region ; pain in umbilical region ; difficult respiration ; oppression of chest; pains in breasts; pains in limbs.

(After supper). Pain in wall of thorax.

( Warmth), Pain in back teeth ; pain in sternum.

Amelioration p. 107

(Motion), Pain in parietal bone ; pains in back teeth ; drawing in thumb, etc.

(Moving arm). Pain in elbow-joint.

(Rubbing), The pains.

(Stooping), Screwed-in feeling in head.

( Walking), Short respiration.