Lactuca

Lactuca virosa, Linn.

Natural order, Compositje.

Common names, Poisonous Lettuce; (Germ.), Gift-Lattich; (Fr.), La laitue vireuse.

Preparation, Tincture (prepared from equal parts of the expressed juice of the herb and 80 per cent. Alcohol).

Aidhorities. (Nos. 1 to 37 from Journ. f. Horn. Arzneim., vol. 2, collection of Dr. Ed. Seidel.) 1, “S,” provings with tinct., 10 to 30-drop doses, and with 3 to 4-grain doses of the extract; la, same, effects of teaspoonful doses of the fresh juice of L. sativa; 2, Ernst, effects of 20 drops of tinct. ; 3, Espe, 10 drops of tinct.; 4, Theine, 40 drops of tinct., and 2 to 4 grains of extract; 5, Piper, 16 drops to ^ an ounce of tinct., and 10 grains of extract; 6, Hence, 10 drops of tinct.; 7, Netolitzky, 4 to 6 grains of extract; 8, Helbig, 40 to 120 drops of tinct.; 9, Preu, 5 to 10 drops of tinct.; 10, a girl of twenty-six, 20 drops of tinct.; 11, a girl of fifteen, 20 drops of tinct.; 12, a girl of sixteen, 1-2 grains of extract; 13, a girl of nineteen, 2 grains of the extract; 14, a girl of twenty-two, 2 grains of extract; 15, a woman of thirty, 2 grains of extract, and 20 drops of tinct.; 16, Angry, Traite des Aliments de came, from the exhalations; 17, effects of 10-15 grains of Parisian Lactucarium, Rothamel, Heidelb. khu. Annal., 5, 2, 277; 18, Tott, Lactucarium virosum. Rust’s Mag., 43, 1, 138 ; 19, Halle, Gift-historie, Berlin, 1787, p. 228 ; 20, Gmelin, Geschichte der Pflanzengifte, 1777, p. 486; 21, Vicat, Plant, ven. de la Suisse, p. 209; 22, Wibmer, Wirk. der Arzn., 3. 3, p. 301; 23, omitted ; 24, Dioscorides, Mat. Med., L. IV, c. 55 ; 25, Pliuiu?, Hist. Nat., xix,_8 et 18 ; 26, Silesius, Krauterbuch, 1577; 27, Richter, Arzueim., 2, p. 605; 28, Kolb, Broniatologie, 1829, p. 209 ; 29, Brach, Arzueim., 2d ed.; 30, Sacs and Dulc, Arzueim.; 31, Candou, Contr. Med., etc.; 32, Voigt, Lehrb. d. Pharm.; 33, Schroeder, Apothekerbuch, 1686; 34, Francois, Rev. Med., 1824; 35, Dierbach, Arzueikrafte der Pflauzeu, 1831; 36, Glaser, in Braudes Archiv, 18, p. 252 ; 37, Ganzel, Diss. de Lactuca sativa, 1819; 38, Austrian Sac. Allopath, physicians, Zeit. der Gesell. der JErz. zu Wien., 1847, provings Avith the extract, to 30 grains at a dose; 39, Schopf, Lehrbuch der Pharm., experiments with dr. of Aust. Lactucarium ; 40, same, experiments on two persons with doses of 1-| dr.; 41, Fronmiiller, loc. cit., effects of doses of to 62 grains of Lactucarium, Syrup. Lact. and Lactucin, in several cases ; 42, A. Boe, poisoning of a family by eating a salad of L. virosa. Bull. Gen. de Therap., from Biblioth. Horn., Ang. 1876.

Mind p. 488

JEinotiofial, Lively mood (secondary action)

Merry delirium, which began about midnight and increased until morning; sang, jumped about on his bed, and played all sorts of antics (boy)

In the evening after grief, stupefying headache, violent contraction in the larynx, inclination to weep caused by the grief; though Lactuca seems to cause sadness with exalted fancies, so that the worst fears and apprehensions are aroused by the merest trifles (after twelve hours)

Internal uneasiness, anxiety (after eight hours)

Extremely ill-humored from the slightest cause (second and third day),h

Fretful mood, with disinclination to work (second to eighth days)

She is fretful, excited by trifles, and aroused to anger (first day),^h

Very fretful but depressed mood (first day)

Peevish mood (first day)

Intellect Hal, Unusual disinclination to work, ill-humor; it does not trouble him in bed (second day),h

Diminished power of thought (after a quarter of an hour)

Mental labor cannot be accomplished; the thoughts become confused; or no connected train of thought can be carried on (first hours)

Stupefaction

Head p. 488

Confusion and VertUjo. Confusion of the head; in morning (second day ),*; (second morning)

Confusion of the head, lasting twelve hours

Confusion of the head in the morning, as after a debauch (second to fifth day)

Confusion of the head, in the morning after rising, with pressing from within outward in the forehead and orbits (after eight hours)

Confusion anddulness of the head (after one hour)

Somewhat confused in the head (after one hour),h

The head is confused and heavy (second morning)

Confusion in the forehead (after one hour)

Confusion and a feeling of heat in the forehead (while bruising the fresh herb)

Confusion in the forehead externally, alternately more sensitive, now in the right, now in the left frontal eminence ; on stooping, there is at times short transient stitching through the left eminence (second, third, and fourth days)

Confusion in the right side of the forehead, in the morning, for several minutes

The head is befogged, dizzy, though without impairment of the power of judgment

Vertigo; also from the exhalations; (from 10 to 15 grains of Parisian Lactucarium),”; (from Lactucarium Genuinum)

Even the odor causes vertigo

Vertigo ; it suddenly became black before the eyes; the threads ran together while sewing; but if she looked off of her work for some time vision became better (after half an hour, and recurring several times during the day)

Vertigo in a warm room, with a feeling of too great fulness in the head (after half an hour)

Vertigo and heaviness, especially in the occiput (soon after taking, and lasting a long time)

Vertigo, together with heaviness in the limbs,h

Slight vertigo (immediately),h

Whirling vertigo, lasting half an hour (after half an hour)

Dizzy and confused in the head, as if she would fall; as if she had not slept through the night (soon)

Dizzy and heavy, especially in the occiput (soon after taking, and lasting a long time)

Somewhat dizzy in the head, in the morning on rising (second day),f

He became dizzy on suddenly moving the upper part of the body, in the forenoon (first day)

Lactuca intoxicates from eating it, or even inhaling the fumes when cooking

GeiieVdl Jlefld, Heaviness in the head, with some transient stitches in the forehead, especially in the region of the left frontal eminence (after one hour)

Headache, in the afternoon (first and third days); (first night and second morning)

The head seems too large, distended, with slight vertigo (after a quarter and half an hour)

Some headache, as if full and confused (after half an hour)

Dull headache (after three hours)

Dull headache lasts for a long time (after three-quarters of an hour)

Dull headache, especially in the forehead (after two hours)

Dull headache, with great indolence and physical prostration (first day)

The head is very painfully shattered by slight cough, so that a whirring and pressing remain in it for a long time afterward (first day)

A waving pulsating sensation in the head, while at rest in the forenoon (first day)

Shaking and swaying in the brain on every motion of the head, so that it threatened to make her dizzy, and she was obliged to close her eyes in order to relieve it; for a short time (after one hour)

Forelieud. The forehead is hot, with burning pressive pain in it, in the evening (first day)

Transient frontal headache, in the morning on waking (second day)

Drawing pain in the forehead

Indefinite, transient, drawing headache, extending from the temples toward the forehead (after a quarter ot an hour)

Slight pressure in the frontal region gradually increases, and becomes at last decidedly painful (after ten minutes), (from 2 grains of the extract)

Pressive pain in the forehead, aggravated by the warmth of the room (after four hours)

Sticking pressive pain in the forehead, as from a dull knife (after twelve hours)

Some dull jerks in the frontal region, the first hour

Pressive frontal headache after slight mental exertion, involving the eyes (after twelve hours)

Pressive frontal headache constantly becomes prominent, accompanied by a feeling as if the whole brain were loose (after two hours)

Temj)les. Dull pain within the head, in the fore and upper part of the left temple, on violently moving the head sideways while washing the face, aggravated on each renewed shaking of the head ; lasting in a slight degree, aside from this motion, for two hours (after a quarter of an hour)

Pressive pain from within outward in both temples,*. Constant pressing-outward pain in the left temporal region, sometimes shooting through the whole head (after ten hours)

Tearing pain in the right tem- 2)oral region (after three hours)

Fe/'tex. Pain in the region of the vertex (after half an hour)

A small spot on the vertex is painful more externally (clavus hystericus), in a woman of 25 (after two hours),. viatftiS» A seated dull pain in a small spot on the left parietal bf)ne, in the afternoon (first day)

Extremely painful drawing in a small spot on the right parietal bone, which is also painful to touch, in the afternoon (first day)

Sharp pressive pain in one side of the head, as if on the bone (after three hours)

Heaviness and pressure in the occiput

Indefinite painful sensation in the occiput, and here and there in the head, the whole forenoon

Dull pain and heaviness in the occiput (after one hour)

Pressive tense feeling in the occiput, with heat in the forehead and cold hands (first hours)/.

Compressive pain in the occiput

A pressive heavy feeling in the occiput, the whole afternoon (first day)

llx‘te)‘nal Head. A small painful spot suddenly appears near the crown externally, which is still more painful when touched (after five hours)

Eyes p. 490

Weakness of the eyes (soon),h

Weakness of the eyes for a few minutes, during the first hours

Slight transient burning in the eyes, Biting in the eyes, especially in the external canthi, so that she is obliged to rub them much, which, however, makes them worse,®. Biting pain in the left inner canthus (after one \\owv)

BroiV. Transient griping above the eyebrows (after a quarter of an hour)

Extremely acute pressive pain in the glabella, lasting ten minutes (after ten and fourteen hours)

Lids. Margins of the lids covered with mucus (first and second days)

Slight burning in the lids during the day, while writing (first day)

Burning pain in the lids, especially of the right eye, with dimness of vision and dilated pupils (first and second days)

Ball, Pressive pain, with a feeling of tension in the right eyeball (soon)

Pupil, Dilatation of the pupils,"^'; (6 to 8 grains of Paris Lactucarium)

PwptYs veris much dilated; in the boy especially the iris was almost invisible (second day)

Vision. Vision became dim, with burning in the eyes

Weak dim vision (from frequent eating of lettuce)

Vision impaired ; the eyes seem clouded, but the film disappears on looking intently at anything (after half an hour)

Vision is periodically and momentarily obscured by a slight film, in the forenoon (first day)

He seeks here and there before he can find anything (after a quarter of an hour)

After closely examining the capital letters in a newspaper he mistook M for P, ana O for V, and the effort to read caused strong congestion of the eyes (boy; second day),*l

Unable to distinguish anything. On trying to read could not make out a single letter, large or small (man and woman; second day),'l

On stooping, inuscje volitantes, after dinner (after five hours)

Visual hallucinations (in delirium); fancied he saw an inkstand, a soldier, etc., on his bed (boy; second day)

Ears p. 490

Alternating drawings in the ears

Some dull stitches, followed by tension in the left ear (after ten hours)

Hearing. Slight humming and feeling of fulness in the head and before the ears (after half an hour)

Roaring in the ears; (first night)

Violent whirring before the ears, in the evening in bed (first day)

Nose p. 490

Frequent sneezing, which aggravates the chest-troubles (fifth day)

Catarrh, leaving soreness in the nose, with dryness

A peculiar pressing-asunder pain in the tip of the nose, in the afternoon (third day)

A peculiar indescribable odor before the nose, with a similar taste in the mouth (first day)

Face p. 490

Sickly expression (after several repetitions of 6 to 8 grains of Parisian Lactucarium)

Face pale, distorted

[HO.] Tense crawling sensation in the face (after a quarter of an hour)

Swelling of the lymphatic glands in the lips (second day)

Fine twitching in the lips (after eight hours)

Stitches extending sideways in the chin (at the exit of the submaxillary nerve), (after half an hour)

Loath p. 490

Teeth and Gums. Pain suddenly appearing in the left lower back teeth, as though a diseased tooth were twisted about

Aching of the gum in a cavity while chewing (third to eighth days)

Tongue, Tongue coated white; (first and second days)

Tongue thickly coated with mucus (from 10 to 15 grains of Parisian Lactucarium)

Constriction beneath the tongue (as after ink), (soon)

The tip of the tongue pains as if burnt (soon after, and second day)

Geneva! 3Mouth, Dr guess of the mouth; without thirst (after four hours)

Tension in the posterior portion of the mouth, and especially of the palate, which constantly obliges spitting of saliva

Saliva, Accumulation of saliva (after a quarter of an hour)

Greater secretion of saliva than usual in the mouth,h

Saliva increased, acid (after one hour),h

Taste, Flat taste (from 10 to 15 grains of Parisian Lactucarium)

Bitter taste (after a quarter of an hour)

Bread and butter leave a bitter taste in the mouth (after three-quarters of an hour),h

Throat p. 491

Tenacious mucus accumulates in the throat, in the morning (first days),h

Slight burning in the throat (soon after taking); towards evening (first day),k

An unpleasant feeling in the throat, as if the part had been exposed to too great heat of the stove (after six days)

Rawness in the throat, after lecturing (after twelve hours)

Some rawness and scraping in the throat (after one hour); and in the afternoon (first day).

Mucus accumulates in the fauces (after one hour)

Swallowing is difficult, with a feeling of burning and rawness on the uvula

Swallowing is difficult, not as from an obstruction in the pharynx, or from a constriction, but because the pharyngeal muscles refuse to act (after a quarter of an hour)

Sticking-drawing pain, extending from the right submaxillary gland to the tongue and ear (after three hours)

Stomach p. 491

Appetite, It caused appetite

Increased appetite (fifth day); at noon

Appetite and loss of thirst (third day)

Diminished appetite at noon (second day)

Loss of appetite (from 10 to 15 grains of Parisian Lactucarium)

No appetite

No appetite at noon, eating is repugnant to her (first day)

Appetite for bread and meat fails (third day)

Thirst, Increased thirst (first day)

Much thirst the whole da)q beginning in the morning after rising (fifth day)

Eructation, Eructations

Frequent eructations (first day) ; during the day

Frequent eructations (tasting somewhat of the bitterness of the extract), lasting only a short time

Frequent eructations, at first without relief, afterwards with relief of the tightness of the chest (soon after, and frequently during the day)

Slight eructations

Frequent eructations of air (after one hour),'; (first day)

Frequent disagreeable eructations, which cause a transient feeling of coldness along the oesophagus, and leave a long-lasting bitter taste (first day, and soon after taking)

Acrid eructations several times during the afternoon

Acid, acrid eructations (after half an hour)

Nausea and Voniitinf/. Nausea; (2 scruples of Lactucarium); soon,*; (after a quarter of an hour)

Nausea and eructations (soon)

Nausea and vomiting (from large doses of Lactucarium)

Nausea and vomiting, continuing all night (man, after four hours)

Nausea, with oppression in the pit of the stomach, in the morning (after eight hours)

Some nausea (after one hour)

Frequent nausea (from 10 to 15 grains of Parisian Lactucarium)

Qualmish sensation in the stomach

Qualmish sensation in the abdomen (second morning)

Feeling of qualmishness in the chest, from afternoon till evening (first day)

Inclination to vomit

Vomiting of ingesta (woman, after twelve hours)

StoniacJi, The pit of the stomach is retracted, and there is a slight pain in the stomach, which is aggravated by pressure (after half an hour)

Feeling of warmth in the stomach, soon after taking, accompanied by nausea rising into the throat, and aflat taste at the root of the tongue, which within a quarter of an hour changes to icy coldness of the stomach and f/troat

Feeling of coldness of the stomach (from Lactucarium)

Crawling cold sensation in the pit of the stomach and epigastric region, with frequent eructations (alter half and one hour)

A not unpleasant feeling similar to coldness in the epigastric region (after half to one hour)

Constant sensation like that felt after sitting long bent in an unusual position, in the epigastric region and sternum (after twelve hours to eight days)

Tightness in the pit of the stomach, followed bij true precordial anxiety

Pressure in the stomach,^®. Pressure in the stomach (from 10 to 15 grains of Parisian Lactucarium)

Pressure in the stomach, without having eaten anything (second morning)

Pressure and fulness in the pit of the stomach (first day)

Violent pressure in the stomach, with fulness as if it would burst (after one hour and a half); then crawling beneath the right mamma, and a sensation as though a bladder formed, like a distension and pressing outward, of the size of the palm of the hand ; followed for some hours by a desire for stool, which does not take place; after an injection of water, two quite solid masses of faeces are evacuated,®.!

Violent pressure in the region of the cardiac orifice of the stomach (after one hour and a half)

Pressive pain in the pit of the stomach, with difficult respiration (after fourteen hours)

Stitches at the entrance of the stomach (after one hour)

The stomach was relieved by the emission of offensive flatus (after one hour)

Standing bent over relieves the stomach (after half an hour)

Abdomen p. 492

Hfjpochondrla. The hepatic region is swollen ; external pressure causes tensive pain (second day)

Liver swollen hard, so that it cannot remain under the short ribs, with slight pressive pain (third and fourth days)

Pinching in the left hypochondrium, for several hours in succession, especially during rest

A dull pressure in the right hypochondrium, in the evening (first day)

A sudden stitch through the right hypochondrium, after eating

Several dull stitches and a feeling of heaviness in the right hypochondrium (first day)

Sharp stitches in the right hypochondrium, extending to the back, which leave behind a dull sensation (after half an hour)

Some dull jerks in the hypochondria, especially in the right (first day)

Dull jerks and stitches in the right hypochondrium, seldom in the left (first day)

Burrowing pain in the hepatic region (after eleven hours)

Periodic drawing in the hepatic region (after five days)

Pressive pain in the hepatic region (after two hours)

Bruised feeling in the hepatic region, in the morning (fourth day)

A violent stitch shoots through the region of the spleen several times (fifth day)

TJnihilicnl. Periodic griping above the umbilicus; worse when the legs are crossed (first, second, and third days)

Sensitiveness of the umbilical region (soon)

GetieVfll Abdomen, Distension of the abdomen (soon)

Diminished peristaltic action of the bowels

Some rumbling in the abdomen (soon)

Rumbling in the abdomen, chiefly in the umbilical region (after one hour)

Rumbling in the abdomen during dinner (first day)

Rumbling in the abdomen after dinner, and some dull stitches in the precordial region (first day)

Rumbling in the abdomen soon after eating, also with slight griping (first day),'; with eructations affording little relief, and gurgling in the stomach, borborygmi in the abdomen and emission of flatus, affording more relief; pressure in the pit of the stomach changes to anxiety, concentrates itself more under the sternum, and constantly alternates with burning and a feeling of coldness (after half an hour)

Flatulence

Flatulence moving about in the abdomen (first day)

Several emissions of flatulence in the evening, which had previously caused griping in the abdomen (third day)

Emission of much offensive flatulence, which first rumbles about the abdomen (third day)

Disagreeable feeling of warmth in the abdomen (fourth day)

Feeling of fulness in the abdomen (after two hours)

Feeling of fulness in the abdomen, especially in the right side, which impedes respiration; relieved by discharge of flatulence upward and downward (first day)

Feeling of fulness in the abdomen, with periodic rumbling and some emission of flatulence (after half an hour)

The abdomen is tense, especially in the hepatic region, the whole evening (first day)

A painful pinching sensation in the abdomen, during and after breakfast (after half an hour)

Griping in the abdomen, with urging to stool, but only flatulence passes, in the forenoon (second and third days)

The griping and cutting in the upper abdomen are worse during and after dinner, and oblige him to bend together (second day)

Transient griping in the upper abdomen, in the morning in bed (after eight hours)

Dragging downward, heavy sensation in the abdomen, after breakfast (after three-quarters of au hour)

Feeling as if a weight were lying upon the abdomen, especially upon the umbilical and epigastric regions; worse Awhile standing (after nine hours and second day)

Violent cutting, with painful rumbling in the whole abdomen, followed by diarrhoea-like, slimy evacuations (after six hours)

Fine cutting and griping in various places in the abdomen (second and third days)

Violent colic (man and woman, after four hours)

Rectum and Anus p. 493

Several hemorrhoidal tumors about the anus, with a sensation of twinging in the rectum; after the discharge of a hard stool there always follows a somewhat thinner stool; lasting eight days.f

Transient drawing in the anus (first day)

Pressing in the anus, after a soft stool

Some prickling in the anus, towards evening (first day)

Desire for stool, which however does not take place (first day)

Stool preceded by urging and griping (after two hours and a half)

Stool p. 493

Diarrhoea. Evacuations of the bowels are rather promoted than retarded

Diarrhoea

Sometimes diarrhoea (from Parisian Lactucarium)

(The customai’y obstruction alvi was lessened)

The evacuations of the bowels become smaller (mushy), and take place more frequently than usual; two to three times in twenty-four hours

It causes easy stools

Easy stool, though no diarrhoea

Two soft stools (first day)

Two pasty evacuations, contrary to habit, during the first twenty-four hours

It obliges him to go to stool, with a feeling of great weakness; only a little is passed with difficulty (after two hours and a half)

Stool with a feeling of general weakness and "weariness, so that he Was unable to sleep; yawning and accumulation of water in the mouth (after half an hour and one hour)

Frequent urging to stool, followed by stool with hard pressing, and succeeded by bruised pain in the anus (sixth day)

Stool hard (after twenty-four hours)

Stool at the usual time, but hard ; for several days

Stool hard aud dry, only resulting after long pressing (three to six days),Constipation. Sometimes causes constipation (Parisian Lactucarium)

Constipation for two days, followed by a very hard and lumpy stool, with burning in anus (fourth day) Stool scanty and dry

Insufficient stool (second day)

Delayed, hard stool (second and third days)

Stool more seldom, and harder than usual,h

Stool, which usually occurs regularly in the morning, occurs twelve hours later, and is harder than usual (second day)

Stool omitted (first day)

Stool entirely wanting (fourth day), and only follows after forty-eight hours; is hard and passed with pressure

Urinary Organs p. 494

Bladder. The increased amount of urine that has collected presses and drags upon the bladder, during the morning hours (first to fourth day)

Twinging pressing sensation in the region of the bladder (second Urethra. A constant sensation white sitting still as though a drop were flowing through the urethra (the whole second forenoon)

Slight burning in the urethra, especially in the orifice (first and second days)

Urging to urinate, with periodic drawing in the glans penis, which shoots through the whole body (after eight hours),*. It increases the discharge of urine

Is obliged to urinate more than usual

Very frequent discharge of urine clear as water (first and second days)

Urine, Urine increased and more frequently voided

Urine increased during the first twenty-four hours

Urine increased in quantity and more frequently voided; she is even obliged to rise at night on account of it, contrary to habit *®.

Increased secretion of urine (first day)

Secretion of urine increased without being obliged to pass urine more frequently than usual (fifth and sixth days)

Copious secretion of urine

More frequent and profuse discharge of clear urine (after six to twenty hours)

It increases the diuresis

Increased diuresis, lasting several days (after several hours)

Diminished secretion of urine

Urine yellowish, clear, smelling of violets

Urine brown, hot, and causing burning in the urethra (second day)

Sexual Organs p. 494

31 ale. Persistent swelling of the lymphatic vessels of the penis after erections in the morning (second day)

Painful erections during the morning sleep (first day)

Dull drawing at the root of the penis (second and third days)

Sharp drawing in the right spermatic cord and down the inner side of the leg (second day)

Desire for coition seems increased

(It removes lasciviousness and voluptuous dreams),®®.]

Emission (third night)

Emissions twice during sound sleep, without his knowledge (first night)

Female, It promotes menstruation

Menstruation six days too early

Menstruation occurs four days too early, with some cramplike pain in the abdomen

Respiratory Organs p. 494

Larynx and Trachea. Feeling of dryness and scraping in the larynx and upper part of the chest

Feeling of scraping disappears, while the feeling of fulness in the trachea continues

On bending the body backward, the fulness in the trachea is somewhat relieved

Rawness in the larynx (after one hour)

Rawness in the trachea obliging deep breathing (after one hour)

Voice. Greatly increased register of the voice (after twelve hours)

Hoarseness

Hoarse and raw in the throat in the morning (second day)

Hoarseness in the evening (first and second days)

Cough, and Expectoration, Some cough, with a dry, burning sensation in the throat (fifth day)

Periodic cough in short paroxysms, shaking the abdomen (first and second days)

Frequent cough (second day)

Tickling in the throat provoking frequent cough (second day)

Tickling in the throat

■j- From the seeds of Lactuca, in wine. provoking frequent cough, with a feeling of constriction over the whole chest (first and second days)

Incessant spasmodic cough, which threatens to burst the chest; it is always caused by a peculiar tickling in the fauces, which in turn seems to he produced by a sensation of suffocation in the throat (third to eighth day), (and lasting still longer at times)

It provokes a hacking cough at times (soon)

(The cough, which before the proving had been easy and loose, changed to a dry, barking, painful cough), (second day)

Some dry cough now and then (first two days)

* Dry cough in short paroxysms, with shaking of the chest and occiput (after one hour)

Hollow, dry, spasmodic cough in the forenoon (third day)

(The dry cough which he usually had before the proving, especially on change of temperature, almost entirely disappeared)

The cough becomes more violent, the paroxysms longer, and with expectoration of mucus (after two hours)

Free expectoration

Much mucus is expectorated by the short cough (first day)

JRespivdtion, Increased frequency of respiration

Respiration 27.2 (before taking), 27.8 (after taking), 27.3 (next morning), (average of all cases)

Inclination to take a deep breath

Frequent inclination to take a deep breath

Frequent desire to take a deep breath while sitting with the body bent forward (after one hour)

Constant hunger for air (after half an hour)

Little sleep, on account of difficult breathing; griping and pressive pain in the chest (second and third nights)

Shortness of breath lasting twelve hours

Short and difficult respiration

Tightness of breathing, heaviness upon the chest, lasting two days

Oppressed respiration (from 10 to 15 grains of Parisian Lactucarium)

Oppressed respiration, with frequent desire to take a deep breath (first and second days)

Dyspnoea and suffocation, somewhat as after inhaling acrid vapor, with dry, hollow hacking, in the evening after lying down (second to fourth day)

While walking and standing it seems as though the breath could not be expired, in consequence of an almost spasmodic constriction in the umbilical and epigastric regions; is frequently obliged to take a deep breath (after nine hours to tw'o days)

Chest p. 495

Feeling of heaviness of the chest, in the evening, with a feeling of filling of the air-passages (after twelve hours)

Pain in the left chest, aggravated by the short hacking cough ; the same sensation in the right half of the chest was also caused by coughing (after three hours)

Sensation after waking, in the lower anterior portion of the thorax, especially the left side, like that felt in the muscles after physical exertion (second day)

The wdiole chest is full, painful, as if beaten, with slight trembling in it (after one hour)

The feeling of fulness in the chest increases towards evening (first day)

Feeling of anxious fulness in the chest (after four hours)

Feeling of tightness in the chest, which is felt about the heart, in the afternoon (first day)

Feeling as though the thorax were too tight and constricted (fourth day)

Wakes from sleep several times at night on account of great tightness in the chest, so that he suddenly rises up anxious, and in the morning is very tired (first night)

A sensation of orgasm in the chest suddenly causes a transient tightness, with subsequent spasmodic pain in the chest externally (first

Readily attacked by orgasm and tightness of the chest after moderate exertion

She feared to take a deep breath on account of tightness in the lower portion of the chest; there was then felt a slight shock (after two hours and a half)

Frequent alternations of tightness in the chest, heaviness on the chest and need of deep breathing; yawning and stretching relieved for the moment

He is sometimes awakened from sleep at night on account of great tightness of the chest, so that he suddenly starts up anxiously (first night)/.

Constrictive sensation, with a feeling of heaviness low down in the chest, oppression and increased warmth, periodically increasing and decreasing, lasting through the day (after one hour),h

The thorax seems constricted; on deep breathing he is unable to expand it completely (after ten hours, lasting till eighth day)

Feeling as if the region of the short ribs, especially the right side, were spasmodically constricted (after eight hours, lasting till fourth day)

The chest feels compressed, tight, especially when sitting bent over

On deep inspiration, the breath does not completely fill the chest, but without the slightest painfulness in the chest (first hour)

Pinching and pressure in the upper half of the chest, with a sensation of tightness and inclination to yawn and stretch the upper part of the body (after a quarter of an hour)

The dull, painful sensation in the chest is increased by deep breathing

Dull, drawing pain in the chest in the morning in bed, increased after rising (after twenty-four hours)

Dragging and orgasm in the chest, compelling rapid respiration (first day)

Periodic twingings in the lower portion of the chest, with a feeling as though the thorax were too tight (fifth day)

Pressure in the upper part of the chest, and weakness even to sinking down, after walking in the open air (fifth day)

Violent pressure in the middle of the chest (first and second days)

* Cramping, pressive joins in various parts of the chest (first, and also sometimes on the second day)

Feeling as of a strange weight in the chest while walking in the open air

Heaviness, like a hundredweight upon the chest; she was obliged to loosen the clothes; everything seemed too tight, and impeded respiration (first day)

Oppression of the chest, with dull pain beneath the sternum (after eleven hours)

Feeling of oppression of the chest; she is often obliged to take a deep breath and to rise from her sitting, bent position, and stretch up the upper part of the body in order to relieve it (first day)

Slight oppression of the chest from both sides and beneath the sternum, followed by a feeling of warmth in the rest of the thoracic walls (after half an hour)

Great oppression of the chest, with periodic twinging pains in various parts (third day)

Anxious oppression of the chest, with inclination to take a deep breath and yawn (first and second days)

Transient stitches at times in the left lobe of the lungs, with difficult breathing (fourth day)

Some transient stitches in the region of the cartilages of the upper false ribs (after one hour)

Violent, sore pain in the chest on sneezing once, which afterwards changes to a pressure (soon)

The whole chest is painful while sneezing

A waving sensation rises several times from the abdomen into the chest (after one hour)

He cannot endure anything tight about the thorax (after half an hour)

Sitting upright relieves the chest

JCroilt. Feeling of fulness in the chest, beneath the sternum and more towards the left side, extending to the clavicle, obliging him to take a deep breath (after one hour and a quarter)

Pressure and tension beneath the upper part of the sternum on moving

Slight pressure beneath the sternum, especially if the hand were pressed against it (second day)

Transient pleuritic stitches to the right of the middle of the sternum (after half an hour)

Sides. Dull pain in the left side of the chest, near the middle of the sternum, necessitating deep breathing; soon after, the same sensation in the corresponding place in the right side of the chest, more towards the upper part, which was soon relieved, while it continued longer in the left side (after one hour)

Pressure in both sides of the chest, aggravated by inspiration, in the morning (second day)

Pinching, dull, sticking pain, which becomes seated in the upper part of the left side of the chest, with tightness of the whole chest, which periodically becomes more extensive

Dull stitches in the right side of the chest, which leave a spasmodic jerking sensation (after two hours)

Dull stitches in the lower portion of the right side of the chest, extending towards the back

Dull stitches from the left side of the chest to the scapula (first day)

Several sharp stitches beneath the short ribs of the left side (soon)

Transient burning throbbing pain in a small spot in the right side of the chest (after ten hours)

3Lai}linw. It increases the milk

It promotes and increases the secretion of milk which is inclined to dry up

Pulse p. 497

Pulsations 81 (before taking), 88 (after taking), 80 (next morning), (average of all cases)

Rather frequent pulse (half an hour after 1 drachm of Lactucarium)

Pulse not remarkably changed, perhaps a few beats slower than usual

Pulse retarded

Pulse slower (from 10 to 15 grains of Parisian Lactucarium),*k

Pulse slow and tense (after twenty-four hours)

Pulse a few beats slower than usual (first day) *®.

Depression of the pulse from 75 to 62 within an hour and a half

Pulse diminished (from 6 to 8 grains of Parisian Lactucarium taken at intervals of three or four hours during the day)

Pulse reduced from 67 to 60; in some persons the pulse was reduced from 10 to 12 beats, and in one individual still more

Neck and Back p. 497

Neck, Pain in the nape of the neck when coughing (after seven hours)

Tension in the cervical muscles of both sides (after twenty minutes)

Tensive cramplike pain in the muscles of the neck in the right side (after half an hour)

Drawing and tension in the nape of the neck, shoulders, and cervical muscles (first and second days)

Pack. Pain in the spine, extending into the cauda quina, and also streaming through the coccyx (after two hours)

Pinching pain, periodically extending through the back, in various directions

Drawing, frequently extending from the small of the back to the groin towards evening (first day)

Bruised pain in the lumbar region (after ten hours to fourth day)

Extremities in General p. 497

Heaviness of the limbs (first day)

Limbs tremulous and weak (first day)

Great weakness of the limbs, and disinclination to work, in the morning after rising, for fourteen days

The limbs frequently fall asleep (first and second day)

Pain in the limbs

Cramplike pains, here and there (elbows, hands, fingers, lower legs), which impede the function of the limbs; they do not last long, and soon reappear in other places

All the limbs feel bruised, obliging lying in bed the whole day (fourth day),®. ' Superior Extremities.

Drawings in the arms, especially starting from the elbow-joints

Frequent drawing and jerking in the arms (soon)

Periodic drawing and jerking in the arms (soon)

Fine stitch beneath the right arm {^oon)

Shoulder. Transient paralytic feeling in left shoulder-joint (second day)

Pains in the shoulders and limbs (from 10 to 15 grains of Parisian Lactucarium)

Sticking in the right axilla, as from a small sharp instrument, lasting several days; the pain is aggravated by pressure and by raising the arm,*. Wandering tearing pain as if in the bones the joints of the right shoulder and elbow, in the open air ; it afterwards extends, now into the wrist, now into the knees, now into the leg, now into the ankle, neck, temples, etc., for a short time, lasting till the eighth day (after eight hours)

Dull, very transient pain in the deltoid and pectoral muscles, afterwards extending to the shoulders, during rest,h

Cramplike pain on the back of the lower portion of the upper arm, which is relieved by moving it (first and second days)

Dull drawing and feeling of weakness in the left upper arm (first day),k

Pain as from a sprain in the deltoid muscle of the left arm, only while the forearm is bent (after eighteen hours)

J^lhow. Dull drawing in the tip of the right elbow (soon)

ForedVm. Tearing pain in the right forearm, with a subsequent paralyzed feeling in the little finger (after two hours)

Wfist. Drawing pain in the external condyle of the left wrist (after one hour and a half)

Hand, Trembling of the hands

Painful jerkings in the hands

Cramplike drawing in the left hand (first day)

Fh%(f€VS. Feeling of heat in several fingers, which leaves behind a weakness

Pain in the middle fingers of each hand, a kind of tearing (after three hours)

Inferior Extremities p. 498

Ohjective. Gait unsteady; he reels to and fro (soon)

Staggering while walking (from 10 to 15 grains of Parisian Lactucarium),”; on attempting to walk

Great weariness of the limbs and right arm (after half an hour)

Subjective. The limb falls asleep while sitting (first day)

Heaviness of the limbs and tension in the hollows of the knees, while walking

Drawing in the limbs and back (first day)

Painful whizzing in the limbs, in the afternoon, while sitting quietly

Thigh. Jerking in the left thigh (after half an hour, and three hours)

Knee. Tension in the hollows of the knees on rising from a seat; the thighs feel bruised (after eight hours)

heg. Trembling of the left lower leg, in the afternoon (second day)

Feeling of heaviness like a stoppage of blood in the lower legs, while sitting (first day)

Cramp in the left calf Awhile walking, lasting about a quarter of an hour (after nine hours)

Drawing and a feeling of stoppage in the right lower leg, especially during rest

Dull drawing pain with a feeling of stiffness in the right lower leg, at times extending up into the hip

Foot, A pain in the ball of the foot on the digital border of the second metatarsal bone, and in the great toe of the left foot; the toes feel grown together and drawn back, only when stepping upon them (fifth to eighth days)

Pain in the sole of the left foot as from a stone-bruise, during rest, disappearing when stepping upon it

Toes. Sensation beneath the nail of the fourth toe as if suppurating, without any external alteration ; and pain on pressure (third day)

fjreiiernl Sgmptonis.

Objective. It causes good nutrition, and diminishes corpulency

Alarming convulsions in a lying-in Avoman (from the juice of the ordinary salad)

Weariness for twelve hours

Weary and sleepy, contrary to habit (first day)

He is as weary and sick after a slight exertion in the house, as if he had taken a long wall in the forenoon (first day)

Great weariness and sleepiness throughout the day (first day)

Astonishing weariness (after one hour),’l

Great weakness (from 10 to 15 grains of Parisian Lactucarium)

Great weakness, immobility and general exhaustion

General exhaustion (from 10 to 15 grains of Parisian Lactucarium)

Subjective. (A truly enlivening, invigorating power, from Lactucarium, in a hysterical woman)

Increased feeling of lightness (from 6 to 8 grains of Parisian Lactucarium)

Unusual lightness of the body in the open air (after some hours)

Great lightness in the open air, and an agreeable, healthy feeling in the whole body (after twelve hours)

A peculiar indescribable sensation of lightness in the whole body without narcotic effect and without any abnormality of the pulse (from 3 to 5 grains of Parisian Lactucarium)/

Feeling as if the body were swimming, in bed (soon),h

Periodic drawing in various parts of the body (first and second days),h

Sharp, cramplike, jerking pain becomes firmly seated close to those parts of the body which bend (the neck, hypochondria, elbows, hips), and especially occurs in the evening and during rest; it is not in the joints, but only near them, and seems to prefer the extensor rather than the flexor surface, and also to be worse in the morning

Desire for the open air

She recovers in the open air; especially tke chest becomes freer

Inclination to sit upright

Skin p. 499

Inflammation and slight eruption caused on delicate parts of the skin by the external application of the extract

Fine sticking twinging and biting, here and there beneath the skin, suddenly

Slight pain under the skin, here and there, in the limbs, almost like a fine sticking

Prickling pain beneath the skin of the nape of the neck, which gradually becomes seated in a small spot beneath the right scapula,k

Crawling itching on the left toes, and left fingers (third day)

Sleep and Dreams p. 499

Sileephiess, Yawning and stretching of the limbs (from 10 to 15 grains of Parisian Lactucarium)

Frequent yawning; (first day)

It promotes sleep

Hypnotic effect

Inclination to sleep

Inclination to sleep, which, however, does not follow

Great sleepiness (after a quarter of an hour)

Great sleepiness, without being able to completely overcome his previous wakefulness (half an hour after 10 grains of Lactucarium j

Great sleepiness, with frequent yawning (after two hours),**; (first day)

Is obliged to go to bed earlier than usual, on account of great sleepiness

Irresistible sleepiness (from 2 scruples of Lactucarium)

Overpowering sleepiness, with nausea (from 2 scruples of Lactucarium)

It causes sleep (when put into footbath)

She falls asleep while at work, in the afternoon (first day)

Quiet sleep (in a hysterical woman)

Quiet sleep, in one suffering from chronic wakefulness (from 5 to 8 grains of Parisian Lactucarium, taken in the evening)

Quiet and refreshing sleep, when taken in the evening (from 6 to 8 grains of Parisian Lactucarium)

Quiet, natural, and refreshing sleep, with diminished warmth (from moderate doses of Lactucarium)

Quiet and gentle sleep at night, but little sleep in the morning, contrary to habit (first day)

Very good sleep at night (first night)

Sleep at night sound and without dreams

Sound sleep full of dreams (first night)

Sound sleep, with emission of semen without any sensation of it (first night)

Deep sleep, lasting five hours and a half (half an hour after 1 drachm of Lactucarium)

Deep sleep for five hours, without stupefaction (from 1 drachm of Lactucarium)

Heavy sleep, without alteration of the pulse or increase of the secretions (from 20 grains of Lactucarium)

Stupid sleep at night; animot rouse herself from sleep, in the morning

Sopor

Sleeplessness. Sleeplessness (boy)

Little sleep, without special uneasiness (second and third nights)

Kight very restless, with many vivid dreams (first night)

Sleep restless, unrefreshing (from 6 to 8 grains of Parisian Lactucarium, taken at intervals of three or four hours during the day)

Sleep at night restless; awakes in the morning with great confusion of the head

Very restless sleep, wakes almost every quarter of an hour (fourth to sixth night)

Very restless on account of headache, spasmodic cough and febrile heat accompanied by dreams which he did not remember in the morning (third and fourth nights)

Long restless sleep (from 10 to 15 grains of Parisian Lactucarium)

Dreams. She slept all night, but had many dreams (first and second nights)/®.

Sleep full of dreams at night, contrary to habit (first night),f

Dreams in the morning, contrary to habit,”. Sleep at night sound, but disturbed by vivid, unusual dreams (first night)

Voluptuous dreams, with emission, during the morning sleep

Heavy dreams (first night)

Sleep at night sound, but with many anxious dreams; waking with a dull headache

Sleep at night sound, but disturbed by very anxious dreams (of shooting, etc.)

Slept well at night, with remarkable dreams towards morning, as if he were turning around in a circle, with one foot upon a pointed object (first night),k

Fever p. 500

Ch illness. The temperature of the axilla was reduced from 1° to 1]° Cent., by the use of lettuce

Chilliness in a warm room (after one hour)

Chilliness in a warm room ; the hands and feet are cold, with cold creepings over the head and back (after one hour)

She easily becomes chilly during the day (first day)

An unusual sensation, allied to coldness, but not unpleasant

Slight shivering (after a quarter of an hour)

Diminished temperature of the hands

Coldness extending over the head and back, alternating with heat in the face, in the forenoon (first day)

Feeling of coldness in the chest (from 10 to 15 grains of Parisian Lactucarium)

Frequent coldness creeps over the back and head (first hours)

Cold feet (after two and three days)

Shivering as if creeping under the hairs,k

Heat. Temperature 29.9° C. (before taking); 30° (after taking) ; 29.9° (next morning) ; (average of all cases)

Sensation of heat, intolerably dry, especially on the lower legs, coincident with aching like that after excessive exertion in w^walking ; from 3 to 6 A.M. (third day)

Fever ; very decided headache ; even the scalp is painful to touch, increased by tearing, which also affects the joints of the limbs, nape of the neck, and face; towards evening the head became so heavy that she was obliged to incline it forward ; unusually dry, extremely distressing heat in the head and upper part of the body, with icy coldness of the feet, burning and lachrymation of the eyes ; incessant, dry, hollow, spasmodic cough, recurring periodically, increasing to threatened suffocation, violently shaking the chest and head, together with spasmodic and painful constriction of the abdominal muscles, and region of the short ribs; at noon (third day)

Heat in the face, with a feeling of swelling and trembling of the lips, several minutes after taking

Siveat. Sweat, during the night

Slight general perspiration, at night (first and second nights)

Copious perspiration,”k

Profuse sweat

Outbreak of cool sweat (from 10 to 15 grains of Parisian Lactucarium)

Conditions p. 500

Aggravation.

(Morning), Mucus in throat; after rising, pain in chest; pressure on both sides of chest; after rising, weakness of limbs, etc.

(Afternoon), Headache; towards evening, feeling in chest.

(Evening), After lying down, dyspnoea, etc.

(In open air), Pain in shoulder, etc.

( Walling in open air), Pressure in upper chest; feeling in chest.

(After eating), Stitch through hypochondrium.

(Rest), Pain in deltoid muscle; drawing, etc., in lower leg; pain in left sole.

(Standing), Feeling of weight upon abdomen.

( Farm room). Vertigo, etc.; pain in forehead.

( Writing), Burning in lids.

Amelioration p. 500

(In open air). General relief,’; especially of chest

(In bed), Ill-humor.

(Sitting erect). Chest symptoms.

Footnotes

† Experiments with Lactucarium (the inspissated juice) are here included; the French Lactucarium is chiefly prepared from L. sativa, the German and English from L. virosa, the American from L. elongata. Fronmiiller ; Die Narkot. Arzneim., 1869.

† From one grain of alcoholic extract of Lactuca, in water, given to a woman of sixty, who had not recovered from an inflammatory attack in the chest, followed by cough, with pain in the scrobiculus.

† From 5 drops taken three days in succession by a man suffering from complete amaurosis for three years, but otherwise healthy.