Lupulus

Humulus lupulus, Linn.

Natural order, Urticacese.

Common names, Hop, Happen, Houblon.

Preparation, Trituration of the hops.

Authorities, 1, Dr. Bethmann, A. H. Z., 10, 72, proving in a girl aged twenty-three, took tinct. 8 drops first day, 30 drops third and fifth days; 2, same, a girl, aged twenty-one, took 45 drops, and subsequently 100 drops; 3, same, a boy, aged five, took 25 drops of tinct.; 4, same, a man, aged thirty-four, took 1 drop of 2d dil.; 5, same, a man, took a teaspoonful of tinct.; 6, same, a man, took two teaspoonfuls; 7, Dr. Walter Jauncey, Loud. Med. Journ., 1858, p. 699, effects of large dose of “ Lupuline;” 8, same, took repeated doses of Lupuline for six hours, 10 grains every half hour; 9, Same, inclosed myself in a room where Lupuline was being distilled in an open retort; 10, same, effects in a man employed bagging or treading dried hops ; 11, Bauman, Wurt. Corr. BL, 1864 (S. J., 123, 165), poisoning of a child, aged twelve, from being several days in a room where they were picking hops; 12, Fronmiiller, experiments on healthy persons, “Narkot. Arzneim.,” 1869, Geo. D., took ^ an ounce of freshly powdered hops; 13, same. Geo. X., took 2 an ounce; 14, Schopf, “ Lehrb.,” effects of the air in a close room in which hops were stored.

Mind

Frequent starting up from deep sleep, with violent delirium, from which he could only be aroused with great difficulty, when he recognized the bystanders, but immediately feel backward into stupor

The mental functions remain indolent for several months

Stupefaction

Head p. 626

Confusion of the head,"; (third day),h

Vertigo,Increased rush of blood to the head and eyes

Heat in the head ; with confusion and dull headache

Heat of the head and face, with a dull and confused condition of the head (fifth day),h

Pain in the head,h

Violent pain in the head (after half an hour) ; headache insupportable (after one hour); the headache continued nearly two hours after discontinuing the inhalation

Headache

Drawing pain in the head

Dull pressure in the forehead, as after intoxication (after one hour)

Violent pulsating of the temporal arteries

Eyes p. 626

Pupils remain dilated for several months

Mouth p. 626

Tongue thickly coated, with much inclination to be dry

Throat p. 626

Violent pulsation of the carotids

Stomach p. 626

Appetite. Loss of a{)petite,h

Thirst. Great thirst, no appetite

Eructations. Eructations, so that she became nauseated (soon),h

Some eructations of air (soon),h

Eructations tasting of the hops

Nausea and Vomiting. Nausea,h

Nausea continued nearly two hours after ceasing the inhalation

Nausea for two days, and a little retching

Nausea and slight colic

Inclination to vomit (after one hour)

Vomiting

Stomach. Sensation of increased warmth in the stomach, soon,^; (third day),h

Sensation of turning in the stomach, with some nausea, without diminished appetite

Sensation of turning in the stomach, and a feeling as though she were very hungry, without, however, having an appetite (third day)

Abdomen p. 626

Fermentation and some dull pains in the abdomen

Pains in the abdomen (third day)

Dull griping in the lower abdomen, with nausea (third day)

Stool p. 626

Stool softer than usual, with so great urging that he could scarcely reach the closet (after ten hours)

Stool retarded

Urinary Organs p. 626

Burning in the urethra during micturition, which was not Relieved by coffee, as were the other symptoms

Urine retarded

In full doses it acts as a diuretic

Urine dark-brown and clear

Considerable quantity of clear urine, the reaction of which was acid, and sp. gr. 1026; while that passed previously the same day and that on the following day were respectively 1015 and 1020,®.

Sexual Organs p. 626

Diminishes and allays the venereal appetite

Respiratory Organs p. 626

Respiration deep, almost stertorous

Respiration 20 (before taking), 24 (after ten minutes)

Chest p. 626

Pulse 64 (before taking); 80 (after five minutes) ; 78 (after fifteen minutes) ; 74 (after twenty minutes) ; 92 (after twenty-five minutes) ; 86 (after thirty minutes)

Pulse slow, rather full

Pulse slow and intermittent

Frequency of the pulse reduced from 20 to 30 beats a minute (and Dr. Maton lowered it even 36 beats in the minute)

Pulse lower by 30 beats in a minute, and intermittent, accompanied by such an uncomfortable sensation of faintness, that I did not carry the experiment farther,®. Pulse 96 (before taking), 94 (after a quarter of an hour)

Pulse 84 (before the experiment) ; reduced 15 beats (after half an hour) ; fallen to 60, and occasionally intermittent (after one hour) ; regular and of its usual rapidity (twenty minutes after discontinuing the inhalation)

Superior Extremities p. 626

Great twitching of the tendons of the upper extremities

Inferior Extremities p. 626

Paralytic weakness of the lower extremities

Generalities p. 626

Objective. Movements of the body were difficult and unsteady for several months

Occasionally the smell made him so faint that he was obliged to go into the open air ; he described his feelings as a faintness and dizziness

Subjective, Uncomfortable sensation of faintness

Drawing in almost all the muscles in short paroxysms, mostly between the shoulders, and also in the muscles of the arms and hands; these pains shifted from one place to another, “just like rheum- matism

Skill p. 627

Scarlet-like erythema, especiallyover the face; with here and there small pustules

Fever p. 627

Temperature 29.8° (before taking); 30° (after taking)

Profuse perspiration with high temperature

Conditions p. 627

Amelioration.

(After coffee), Immediately, the symptoms