Hydrophobinum

The virus from the mad dog.

Preparation, Trituration with sugar of milk.

Authorities. (1 to 7, provings by J. R. Coxe, Jr., M.D.; Phil. J. of Horn., 3, p. 262;: 1, J. R. C., Jr., took 3d dil. three times a day for four days; la, proving with 6th dil.; 16, proving with 30th dil.; Ic, proving with 3d dec. dil.; 2, Daniel Coxe, aged 17, took 3d dil. in same manner; 2a, same took 6th dil.; 3, Charles Coxe, aged 7, took 6th dil.; 4, N. E. W., aged 18, took 3d dil.; 4a, same took 6th dil.; 5, same took 30th dil.; 6, A. R. S., aged 18, took 3d dil.; 6a, same took 6th dil.; 7, Miss A. S., aged 30, took 3d dil.; 7. «)Same took 6th dil.; 7 6, same took 30th dil.; 7 c, same took 3d dec. dil.; (8 to 18, and a few authorities given after the symptoms, from same reference, no details furnished) : 8, Hering ; 9, “ B.,” Bute ; 10, N., Neidhard ; 11, “ Y.;” 12, “ Schra.;” 13, “ W.;” 14, “ My.;” 15, “ E.;” 16, “ Br.;” 17, “ C.;” 18, Pherson.

Mind

Etnotioildl. Strange notions and apprehensions during pregnancy

Exaltation ; thinks he has something of importance

Singing, in walking through the whole house, entire day

^aug more than usual, but did not feel at all merry ; singing involuntary

Happy disposition, after perspiring in the evening

Exhilarated, felt as if he had received joyful intelligence, all day

During the first two or three days, temper more equable than usual

Felt unusually serious

Had a good cry before going to bed ; felt very sad (third day)

Bitterly crying, with headache

Anxiety of mind, restlessness, with great prostration ;” with pain in the heart;” with the headache

Feeling as if I had heard, or was about to hear something bad; morose and crabbed feelings until 4 p.M. (fourth day)

Mind much depressed ; felt as if something disagreeable was about happen (third day)

Feeling as if something annoying was about to happen ; goes off when thinking of it

He cannot prevent ideas of something awful about to happen, or as if he would do something awful

An indescribable idea, which I could not shake off, of something dreadful about to happen to me; all day feeling as if some great misfortune were about to occur

Irritability

Irritable, with headache

Feel irritable; spoke short to the children (ninth day),’-

Very irritable at trifles

Am extremely irritable, or rather- feel stern (sixth day)

Disposed to get mad

Imi)patient all day

Impatient all day, with headache

Ci'oss and hypochondriac in the evening

Felt very cross ; did not want to converse or see any one

V^ery cross and crabbed until 10.30 P.M., when I fell asleep

Very cross, so much so that my children expressed great surprise; took offence at the merest trifles; scolded my wife and children ; could not concentrate my mind on anything

The last day or two feel more morose; caught myself saying to nephew, in severe tone If you do that again etc., when he was not really in fault

Offended at everything; gives offensive answers

Inclined to use offensive expressions

Thought came into his mind to attack others in a mean way; to cut others with a knife he holds; to throw water he has in a tumbler into another’s lace

Occasionally exhilarated, then again morose, both feelings going off very readily on conversing

Intellect ill. There seems to be two distinct trains of thought operating at one and the same time

Plays chess much better, but cannot relate a story

Undecided about little things

Have found it difficult through the whole proving to think intently, and at times almost impossible (seventh day)

Restlessness in the mind during the forenoon and at noon

A strange oppression and indifference, as if he was unable to do anything if he forces himself; there is no power in the mind

j40.] Dulness and stupidity (second day); at night with restlessness

Memory for words much better

He loses consciousness for a moment

Meld p. 14

Vert(JO. Vertigo while silting, and after rising or walking he staggers

Slight vertigo when rising from a chair (sixth day)

Dizzy, as if he could not hold the head

After stooping <dizzy, and losing sight

Dizzy headache (eleventh day)

Dizzy headache all day, spirits not depressed (third day)

A dizzy dulness in the vertex, he fears he will fall while walking, in the evening

L^O.] Slight dizziness and nausea (sixth day)

While stooping, giddiness on the right

After lying down in bed, a giddy-like shock in the upper part of brain

GelieVill Mead. Rush of blood to the head while lying down

Lightness in head

Lightness (of head) after nausea

Dulness (of head)

Have had all day a singular sensation in head (third day)

Feels as if a leaden ball was rolling about in the brain

Pain in-the head (fifth day)

Slight pain in head and heart (fourth day)

Pain from mouth up through head, and down to back of neck, quite severe

Pain in head, which was very severe till 9 P.M. (fourth day)

Intense pain in head, extending back of forehead to organ of firmness, at 2 P.M.; soon after to whole top of head, or to eyes, lasting all day (second day)

Burning waving towards the head

After moving, turning, stooping, feels as if head would burst

Head feels as if it would split, and a great pressure on top

Dull, heavy pain in the head

Headache all day (fourth day),'*; (sixth day)

Some headache and pain in eyes (sixth day)

(70.] Walked out and had headache, or after walking five minutes felt sharp pain across the eyebrows or up the nose ; felt exceedingly fatigued and weary after a short walk (fourth day).

Headache in the bones

Towards noon slight headache

At noon slight headache, lasting all day

Headache severe; (fifth day)

No pains till 3 P.M., when head ached severely until 9 p.m.,®.

Headache quite severe all day, and implicating eyes; feel lazy, requires an effort to think (fourth day)

Headache quite severe

At 3 p.m. headache very severe

A severe, impatient headache through the whole morning-

A very intolerable, snappish, irritable headache for three days, with the jaws stiff and sore, the hands numb (after nearly a mouth)

Headache alternately with flushes in face

Afternoon pain in head, sick headache

Considerable pressing pain in head (seventh day)

Tearing and shooting-like in the bone (of the head)

Irritable headache; touchinothe head makes it ache (sixth day)

Throbbing headache in forehead vertex, and occiput, down to the neck

Throbbing, pulsating headache most severe in right temple and over right eye

Headache all day, most severe in right temple, beating, throbbing, and pulsating

A slow vacillation or waving of the head from losing something in the upper part of the head

Dulness in the middle of the brain where it waves and moves

Shocks (in head) like dizziness

Headache relieved by cold air

Forehead. Dulness in the forehead, more to the right side

Pain in forehead, in the protuberances, soon

Pain in head, greatest one and a half inches above left eye

Great pain in head, from temj)le to temple, all day

Slight burning pain in forehead

Dull pain in forehead, especially on the left side, with a stupid feeling

Dull, heavy pain in forehead, and sharp, pricking pain in left temple, sometimes attended with throbbing and pinching

Severe, heavy, dull pain in forehead, lasting five hours

During the afternoon and evening, headache over the eyes

Head aches severely from temple to temple (fifth day)

Pressive pain in forehead; with sensation of heat

Pressive pain in forehead and vertex, worse after moving the head and stooping

Pressing pain on top of forehead, while reading and thinking, in the afternoon, with restlessness of mind

Violent pressing outwards in forehead ; the patient put the head towards the wall

At 9 p.m., severe shooting pains in the head over the eyes, and in the temples, also a very violent, aching pain inside of and all over the chest (second day )

Severe headache from temple to temple, of a throbbing, beating nature (fifth day)

Temples, Pain in the temples from the jaws

[HO.] During the day, headache very intense at times in right temple

At 9 a.m., most severe headache in both temples and over eyes unbearable, causing him to cry bitterly, and refuse to take another dose

Boring in temples every second day, in the left, morning (fourth day)

Boring in the right temple every second day; in the left in the morning (fourth day)

Vertex. Could detect no symptoms, save a slight headache on top (eighth day)

Much pressing on top of head ; feels as if a form, fitting top of head, was pressing on it (fifth day)

Pressing pain on top (of head) and forehead, while reading and thinking, in the afternoon, with restlessness of mind

Painful pressure on top, by moving the head, with fever and prostration

Pressing heaviness on top aud to the right (of head)

Pressing shutting on top of head

Beating, pressing on top; painful pressure on top (of head) on moving the head, with fever and prostration

Strange pulsation on top of head

Parietal v. Numbness in left side of head

Right side of head feels stiff, as if it would become numb (third day)

Pressure in left side of head, with boring aud shooting inwards, extends to forehead and eyes, in the evening

Tearing from forehead towards left side

Left side of head is now, and has always been, most severely affected (sixth day)

Occiput, Dulness in occiput, after awhile becoming painful

Slight pain in head, back part (seventh day)

Pressing on occiput, upper side

External Head. My hair, which is usually dry, has become very oily to-day, the first time I remember such an occurrence (third day)

Skin of head seems contracted and pinched up ;fifth day)

Scalp very sensitive

Whenever I put my finger on my head, there is always a strong subsequent pain, lasting a con.«miserable time

Itching in “acquisitiveness in the morning (fifth day)

On right side of vertex something comes from within aud itches

Eyes p. 15

Ohjeetire. Eyes somewhat red and inflamed (the cornea)

No pain, but eyes still slightly red, and occasional stitches in right temple

Eyes bloodshot and painful (fourth day)

Inflammation in eyes during the day (tenth day)

Inflammation of one eye; frothy matter pours out between the lids; pimples around the eye since the bite of a dog in the t^l\gQY

Sabjeetive. Weakness of eyes when looking upwards

Great weakness in eyes, but no pain

Some pain in eyes (eighth day)

Burning in eyes

Headache not severe; pain extends into right eye (fourth day)

Eyes ached intensely/

Soreness in eyes (fourth day)/.

Soreness in eyes, and pain in forehead above them (second day)

Soreness in eyes and throat, and difficulty in swallowing (fourth day)

Drawing, beating pain over the eyes and into the balls

A curious stinging pain in left eye, extending to forehead, over right eye painful, at 9 A.M. (third day)

Tickling and heat in eyes,"; from the neck

lit'OlV, Pain over the left eye previous to retiring (fourth day)

Pain in small spot over right eyebrow, rendered worse by writing

Pain over right eye inwards, pressing the temple

Sharp pain across eyebrows, afterwards burning in the eyelids (fifth day)

Drawing-beating pain over the eyes and into the balls

Lids. Eyelids as if they were lame, or were firmly closed, in the morning

Burning in the lids

Burning in eyeballs

Vision}l, Left eye extremely sensitive to light, and weeps; unusual with me, my eyes being very strong

Dimness of sight, with giddiness

Something moves before the eyes, but always at a distance from the place she looks at

Head p. 16

Rush of blood to right ear, after it a pressure, as if from a dull point

Ears feel very stiff

Buzzing in right ear

Rushing noise, like water falling, in left ear,®-

Nose p. 16

Objective, Frequent sneezing, ceases after his attention is called to it,'k

Often coagulated blood in the nose

Subjective. Pain in nose (second day)

Pain in the nose and right neck and side ; feel very stiff, most about the jaws (fifth day)

Nose pains from thinking

headache extends into the nose

Sharp pain runs up the nose

Nose feels bruised (fifth day)

Tickling in nose

Itching in nose (all day)

Smell, My sense of smell, which is always extremely acute, became painfully so, particularly in reference to unpleasant effluvia; the action of the nostrils was extremely painful

The greatest sensibility to the smell of tobacco; tastes the snuff, while the box is one foot distant

Face p. 16

Objective, Paleness and qualmishness

Quivering in the face

Slight twitchings in face and hands

Face pale yellow, nearly brown

Subjective, Heat in the face after drinking coffee

Heat in face, with redness

Heat in face, and soreness of left cheek, from thinking

It draws about in right side of face

Cbeehs, Quick drawing from the right malar bone towards nose

Feeling as if bitten in the face, left side of mouth

Something seems gnawing right cheekbone (fifth day)

Rending pain in right upper jaw towards the ear; jaws ache with the headache

Shooting pains in upper jaw

Chin, Biting-snapping, with convulsions

Several severe twitches in jaws

Jaws feel stiff, and a disposition to gape

Jaws stiff and sore, with headache (after nearly a month)

Both jaws feel stiff; tingling in cheek-bones (third day)

Jaw quite stiff at times, more painfully so than before (tenth day)

Earache nearly all day, and pressure on top of head most severe

While reading, jaws began to ache; the longer I read, the more they ached ; gaped frequently (seventh day)

It seems to make the jaws ache to write (second day)

Jaws ache severely (second day)

jaws feel sore and stiff; have a great disposition to press the hand against the lower jaw

Jawbone feels quite sore

Mouth p. 16

Teetlt, Teeth feel on edge (second day)

Pain in roots of back teeth

All the teeth ache

Headache and earache extend into the teeth

Teeth very sensitive; pulsation in teeth of upper jaw,’®._ Toothache during pregnancy

Gums, Gums painful

Tomjue, Pain in the root of the tongue and left side of throat (second day),’®._Gen- €i'(lJ 3ToNfh. Feeling of coldness (in mouth), like essence of peppermint

Felt as if the velum pendulum palate was elongated; examining, found it not so, but was slightly inflamed (fifth day)

Have had quite a sore mouth, feels as if thei-e were lumps in it

Have had, for a week previous to taking medicine, a dry, parched mouth, with great thirst; now, mouth full of saliva, and total disinclination to drink (third day)

S(l/iva. Increase of saliva, not more viscid than usual (third day)

Towards noon, slight increase of saliva

Much saliva

Much saliva, not thicker than ordinary (sixth day)

Great flow of saliva and difficulty in swallowing liquids (second day)

Saliva more plentiful, but thin, and of a yellow color (fifth day)

Much viscid saliva (second day)

A large quantity of viscid saliva in mouth, causing me to spit an unusual quantity (third day)

A very large amount of viscid saliva, and an increase of oil in the hair (fourth day)

Saliva more viscid, constant spitting, feeling of general malaise all over, without pain, or knowing where to locate it (fourth day)

Saliva very viscid, not more copious than usual

Saliva very viscid and plentiful, sore throat all day (third day )

A great flow of spittle (third day)

A great flow of raucous spittle (second day)

Much tenacious mucus in mouth and throat

Taste. All through this proving, could not get my food to taste of salt, though I used more than usual

Throat p. 17

Objective. Inflammation of the throat (Braung).

Slight inflammation of throat and fauces as far as I could see (third day)

Throat much inflamed, some difficulty in swallowing

Much mucus in throat and nose (fourth day)

During the day, bile rises in the throat; an unusual quantity of tough saliva in mouth and throat

A terrible pain in throat all day, and great pain in swallowing

Great heat in the throat and around the heart (second day)

Throat feels as though I had swallowed a small quantity of red pepper (fourth day)

At 3 p.m., felt a strange constrictive sensation in back part of throat never experienced before; at 4 P.M., worse, could not swallow without great pain; went off at 6 p.m.; returned in an hour, lasting till 10 p.m.

Violent spasms of throat at 2 p.m., feeling as if I was about to be suffocated ; went off at 9 P.M.

Sore throat

Sore throat all day (fourth day)

Throat feels sore and as if swelled

Sore throat, increased saliva, no inflammation, as far as I could see, though it felt as if inflamed, and hotter than usual (seventh day)

Sore throat, constant desire to swallow

Very slight sore throat, constant desire to swallow (second day)

Sore throat increased, slight difficulty in swallowing liquids, much saliva, rather more viscid than usual (third day)

Sore throat, not able to swallow without great pain (fifth day)

Sore throat and headache all day

Slight sore throat, difficulty in swallowing liquids; this time a real difficulty; epiglottis appeared partially paralyzed (this symj)tom continued three days in several persons, going off by degrees); no difficulty in swallowing solids

Slight sore throat

Throat quite sore, headache in both temples, numbness in both arms, slight pain in lumbar region all day

C^quite a sore throat, constrictive sensation much worse when attempting to swallow liquids, which I could not do without pain ; solids not painful

Violent sore thi-oat, quite inflamed, could not swallow, liquids ran through the nose

Very violent sore throat; soreness over whole body, as if beaten

Soreness in throat from 11 a.m. till noon

Soreness and suffocation in back of throat at 10 a.m.

Throat feels raw and as if about to become very sore (fifth day)

Burning down in the oesophagus

A desire to swallow, and spittle more copious and viscid than usual,h

Constant desire to swallow (third day); (sixth day),h

Constant efiiirt to swallow, or dislodge mucus, which seems glued between nose and throat (eighth day),h

Feeling of suffocation has left the throat, but still I have difficulty in swallowing, also soreness in the eyes, but not the pain above them (third day)

Slight difficulty in swallowing,'a.

Great difficulty in swallowing; sore throat (second day) Just before taking first morning dose, felt as if I was unable to swallow;^ tried a mouthful of cold water, swallowed it readily, but with a kind of aching in throat, followed by a slight burning; this burning lasted all day (fourth day)

Feel as if I was going to have the mumps (second day)

Rending and tearing pain in right jugular bone,". Gnawing in right jugular bone

Stomach p. 18

Apltetite. Better appetite than usual

Appetite today and yesterday perfectly ravenous

Likes cold apple-butter,®. Little appetite in the morning

Aversion and disgust to everything fat, particularly mutton

Thirst, Not thirsty these two weeks

JVflllsea and Voniitinff. Nausea, with pale face, after diarrhoea

Sickness of the stomach after eating eggs or fat meat; nausea, with giddiness and headache

Vomiting of the supper at night

Stomach, Noise in the stomach like bubbles of water; pressure like something pointing

Pressing inwards in pit of stomach after eating

Abdomen p. 18

Uypochottdria. Pressing pain in hypochondriac regions after quick walking

Painful throbbing, like an abscess, in the hypochondriac regions

Gnawing pressure in the left hypochondriac region

Tearing from left (hypochondriac region) to right

Pain in region of liver and right kidney

Conval Abdomen. Difficult and impeded passage of wind

Burning waving and rolling (in abdomen)

Feeling of coldness and burning in abdomen

Violent bellyache

Pressive drawing and wrenching sensations (in abdomen)

Shooting in abdomen

Shooting in right side of abdomen

Iliac Key ion. Glands in groins swelled very much and pained greatly for two hours (sixth day); not much abated (seventh day)

Pain in both groins ; the right groin has two little balls swelled up under the skin, quite painful (fifth day)

Much pain in right groin and slight swelling there at 2 p.m. (fifth day)

Dull pressure above the right groin, on a small, distinct point

A dragging pain in both groins

Rectum and Anus p. 18

Piles protrude

Blood from anus during menstruation

Bright-red blood from anus, with a horrible burning and stinging, like thorns

Sphincter (ani) closes violently

Pulsation outside of anus

Stool p. 18

Diarrhoea

Diarrhoea, without pain, in the morning; with pain in the morning

Softer stool than usual

Urinary Organs p. 18

Kladder. Cold and burning feeling in bladder; pain in sphincter

Urethra. After urinating, flow of prostatic juice

Burning and tenesmus in region of prostate and down urethra

Tickling burning in urethra after urination

Micturition. Urging to urinate

Very frequent urination ; very copious watery urine

Urine. More urine and brighter colored

Urine brown, turbid, with reddish or whitish sediment

Sexual Organs p. 18

Male. Great weakness of the male parts; they feel empty, as if gone; bearing down in urethra

Tickling and burning on corona glaudis, with some greenish pus

Aching in testicles

Lascivious ideas and erection, afternoon

Indifference during erection, and even during coition

Nightly emission in sleep, with dreams

No sperm during coition; the sperm passed off in sleep

Female. During the day, great pain, extending from uterus into breast and right side of abdomen (seventh day)

Bearing down in uterine region

Sharp pains in uterus, shooting down to labia

Slimy leucorrhoea during the proving

Menstruation after fifty days, with headache

Menstruation after two weeks, with hfemorrhoids, pulsation in anus, and weakness of back

Taken three days alter menstruation is over, it reappears in two cases

Respiratory Organs p. 19

Sighing

Sighing, with oppression of breathing

Sighing, with pain in heart

Chest p. 19

Rush of blood from the chest upwards, with toothache during pregnancy

Pain from within outwards, in right side

Pain in left side

Dull pricking pain in left side from head to waist

Heart p. 19

Slight pain in heart and head (fourth day)

Back p. 19

Pain in back and both groins

Aching in loins into back

Aching from loins down to feel

Drawing downwards (in loins)

Extremities in General p. 19

Severe pain in all the joints

Superior Extremities p. 19

Numbness in both arms

Hands numb, with the headache (after nearly a month)

Inferior Extremities p. 19

Heavy bruised feeling in both thighs

Legs felt heavy and throat sore

Generalities p. 19

Chlorosis (Barr, Gross).

Great weakness and prostration

Nervous and irritable (seventh day)

Felt very nervous and much excited (third day)

Feel lazy, requires an effort to think (fourth day)

General malaise all over, without pain, or knowing where to locate it (fourth day)

Feel very bad to-day, severe pain in eyes, and in all my joints

Skin p. 19

Pimples on left forehead, afterwards on the right

Slow-maturing, bluish pimples on face

Trickling in the left cheek, at 6 a.m.

Itching in root of penis

Sleep and Dreams p. 19

Excited, cannot sleep

Admires his own skill in talking fluently Latin in a dream

Subordination, like a servant in a dream

Fever p. 19

Flushes (in the face) and headache alternately

Face sweats, with flushes

Conditions p. 19

Aggravation.

(Morning), Eyelids as if lame; little appetite.

(Afternoon), While reading and thinking, pam on top of head.

(Evening), At 9 oclock, pains over eyes, etc.

(After coffee). Heat in face.

( When looking pinard). Weakness of eyes.

(Moving), Bursting feeling in head.

(Stooping), Vertigo; bursting feeling in head.

(Writing) Pain over eye.

Amelioration p. 19

(Cold air). Headache.

(After meals). Feels better.