Solaninum

An alkaloid, C^HJ^O^ obtained fi ■oni various Solanums, especially from 8. nigrum and S. dulcamara.

Prepare tiou, Triturations.

Authorities. Reil's Journ. f. Pharmacodynam., 1857. 1, Dr. Clams, took ^ grain of the acetate first day, 1 grain second day, 6^ grains third day ; 2, Schopf, Lehrbuch f. Pharm., 4th ed., p. 623, proving of Solanin from 8. dulcamara on four persons; 3, Froumiiller, Khu. Studien, etc., gave to several persons doses of 1 to 4 grains of 8. from 8. tuberosum and nigrum, no symptoms; afterwards took 6 grains; 3a, same, persons took 15 grains.

Mind

Stupefaction without previous excitement

Head

Vertigo

Head hot, heavy, dull, painful

Heaviness of the head

Pain in the occiput

Eyes

The pupils were not much affected, perhaps somewhat contracted

Mouth

Salivation

The pure alkaloid has a cooling, acid, and salt taste, and when chewed, it causes a glutinous sensation iu the pharynx and throat, with scraping, which extends down to the stomach, where it becomes a peculiar sticking pain

Bitter taste.3

Throat

Scraping in the throat

Stomach

Constant eructations

Nausea and diarrhoea

Nausea, and violent ineffectual efforts to vomit

Nausea and vomiting

About 5 p.m., vomiting three times without previous nausea, without pain and without any intestinal symptoms

Abdomen

Rumbling in the abdomen

Urinary Organs

(The next morning, examination of the urine showed albumen!)

Respiratory Organs

Hoarseness

Respiration slightly slower than natural, temperature not affected

Very superficial slow respiration, 15 or 16 to 14 to the minute

Difficult respiration, with oppression of the chest

Oppressed respiration

Pulse

Pulse increased iu rapidity, weak (72 to 88)

Increased frequency of the pulse, sometimes as much as 25 beats, lasting four hours (the next morning, somewhat slower than natural)

The pulse ran up to 95 and 100, was remarkably soft, small, and weak

Pulse rose from 76 to 92 in fifteen minutes; in twenty minutes more it returned to the normal

It caused after ten hours slight slowness of the pulse and respiration, but no change in the temperature

Pulse small, weak, thready

Inferior Extremities

Slight tonic spasms of the lower extremities

The next morning the prover felt quite well, with the exception of some weakness in the lower extremities

Generalities

Weakness

Sensation of great weakness

Sensitiveness to light, noise, and to touch

Skin

Skin dry

Hyperesthesia of the skin ; creeping along the spine when touching the skin ; more easily tickled than natural

Itching of the skin

Sleep

Frequent yawning

Great sleepiness, with inability to sleep

Sleepiness

Sleep very restless, frequently disturbed by frightful dreams

Sleep frequently interrupted during the night, but without dreams

Fever

Extremities cold

Profuse perspiration without weakness