Trimethylaminum

Trimethylamine, CgHyN.

Preparation, solutions.

An alkaloid found in the following plants; Chenopodium vulvaria, Crataegus oxycantha, Sorbus aucuparia. Phallus impudicus, Pyrus communis. Arnica montana. Cotyledon umbilicus, Fagus sylvatica, etc.; also in Herring-brine, Cod liver oil, etc.

Authority. M. Dujardin-Beaumetz, Nouvelles Recherches sur la Trimethylamine, Paris, 1873; 1. effects on himself, of 50 centigrams of the muriate dissolved in water; 2, another person in perfect health took 75 centigrams of the muriate; 3, results of several experiments.

This drug, according to several experiments on patients, etc., diminishes the amount of urea; in one case there was a diminution of over 2 grams during twenty-four hours, in another 2.24 grams, in another a diminution of 3 grams,®.—Pulse 88 (before the experiment) ; 84 (after one hour) ; 82 (later) ; 76 (after two hours). There was not only a diminution in the number of pulsations, but also a modification in the force, as shown by the tracing (it shows no special modification, with the exception of diminution in the force of the heart’s action),®.—Pulse 78 (before the experiment) ; 76 (after one hour); 74 (after one hour and a half); 72 (after two hours); 78 (after four hours),'.—Temperature 37.4° (before the experiment) ; 37.2° (after one hour); 37° (after one hour and a half); 36.8° (after two hours),'.—Temperature 37° (before the experiment); 36.8° (after one hour) ; 36.4° (later); 36° (after two hours),®.