Ailanthus

Authority. 15, C. A. L., Pub. of Mass. Horn. Med. Sac., vol. iv, p. 119, a proving.

[210.] P., a student of medicine, aged nineteen, in good health. Took 1 drop of 1st cent, dilution every hour from 8 a.m., March 4th.

At 10 A.M. Lancinating pain through both temples, and fine prickling pain in left temple. Burning in, and darting pains through the stomach.

12 M. Tired sensation of lower limbs, chills over the whole body as from water, and sharp pains through both lungs.

I P.M. After dinner, sinking feeling in stomach.

3 P.M. Severe constriction of the throat.

8 P.M. Sharp prickling pain in the stomach and temples.

March 5th, 10 a.m. Aching in left lung. Discharge of bright-red blood from the nose, which was swollen.

II A.M. Severe nausea, as from fat meat.

1 P.M. Sharp pain through both temples.

3 P.M. Lancinating pain through the whole lower limbs.

6 P.M. Throat feels very full.

INIarch 6th, 7th, and 8th. No new symptoms.

March 9th, 9 a.m. Bleeding from the nose and sharp pains through both lungs; worse when taking a long breath.

12 m. Mouth very sore, and feels raw and burning, as if from the presence of acid.

1.30 P.M. Lancinating pains in both temples, and deathly faintness of the stomach after dinner, lasting an hour and a half.

4 P.M. Sensation as from a blow in right ear.

6.30 P.M. Trembling of the legs.

March 10th, 8 a.m. Mouth sore and raw, and oozing of blood from the denuded surface. Faint feeling, with nausea. Sharp pains in both lungs, and in the stomach, as from pins.

12 m. Ringing in right ear.

2 P.M. Bruised sensation on the right forearm.

5 P.M. Mouth very sore and painful, discharge of blood from the swollen gums.

March 12th, 8 a.m. Dryness of the mouth, and bleeding from the roof and sides. Nausea in the abdomen.

10 A.M. Sharp pain through the right temple, with nausea.

3 P.M. Pricking pain through left lung. Trembling of the legs. Ringing in the ears, like music.

]\Larch 15th, 8 a.m.. Mouth continues very sore, with discharge of blood and stringy mucus. Teeth feel as if he had taken acid in the mouth.

10 A.M. Pains in lungs return, and trembling of the legs and bruised sensation of right forearm. Constriction of the throat, with sensation of a foreign body there for about ten minutes after every dose of the medicine. Took same doses up to the 25th, with no new symptoms,^\

Additions: Introduction p. 642

The following revision of “Authorities” 3 to 13 is intended to be explanatory, Nos. 15 to 17 are new.

Authorities. 3, J. T. Alley, M.D., North Amer. Journ. of Horn., vol. vii, p. 385, made tincture from flowers just before maturing, of about 1 ounce to a pint; I took it in drop doses four times a day, for three weeks, and gave it to two young men, who took it each about two weeks ; I took it three different times, continuing each time about three weeks; my last proving was with the 1st dil. ; only symptoms common to all provers are given; 4, same, U. S. Journ. of Horn., vol. i, p. 285, Mrs. F.’s symptoms during flowering season ; 5, same, ibid., Mr. M.’s symptoms during flowering; 6, H. Milton, M.D., ibid., vol. ii, p. 668, made tincture from leaves, bark, and woody Ailanthus, and gave a young man 2 drops at 8.15 and 10.15 A.M. (first day), 2 drops (second day, and from the fifth to the fifteenth days inclusive) ; 7, same, a man, aged twenty-eight years, took 3 drops tincture at 5 p.m., and 5 drops tincture in solution at 8.15 p.m., seven days later took 3 drops tincture at 8.30 and 9.15 a.m. ; 8, same, J.’c. L., aged twenty-one years, took 1 drop every hour till he had taken eight doses, and then he took a teaspoonful; 9, P. P. Wells, M.D., Amer. Horn. Rev., vol., vi, p. 268, effects of aroma, and U. S. Med. and Surg. Journ., vol. iv, p. 330, a proving, dose not mentioned (symptom 138) ; 10, same, Amer. Horn. Rev., vol. iv, p. 385, a girl, aged fifteen years, stripped outside bark from the young and tender shoots, and then after writing letters on stalks with a pin, moistened these with saliva, which was rubbed on them with the finger, this was repeated many times, and the juice was thus conveyed to the mouth ; 11, same, effects on a boy, of eating the seeds; 12, W. Williamson, M.D., U. S. Journ. of Horn., vol. ii, p. 668, some little boys smoked the stems likesegars; 13, Hale’s New Remedies, third edition, a resume; (15 to 17, from Dr. Giraud, Thesis, Paris, 1875); 15, effects of the bark on Dr. Hettet; 16, Dr. Robert, who published the first work on Ailanthus in dysentery, experimented on himself with the infusion, see Archives de Naval, 1874 ; 17, Dr. Gerard, took two spoonfuls of an infusion.

General malaise, sensation of feebleness, and dimness of vision and nausea,'^—He found it extremely bitter, causing nausea, sometimes vomiting. After an hour there was very notable diminution of the pulse, of about 10 beats, which persisted for half an hour, after which it rose and became more frequent than normal,*®.—After a quarter of an hour there was nausea, accompanied by anguish, similar to that caused by Ipecac.. Sensation of tightness in the temples. All these synqrtoras increased after half an hour to vomiting; the pulse had increased from 68 to 76, temperature from 37.2° to 37.3°. After this he experienced a peculiar sensation of emptiness in the stomach. Pulse 80. Tenqrerature 37.7°. This was followed by a fall of the pulse to 64, and a sensation of coldness over the whole body. After a few hours there was colic, followed by a soft stooll In another experiment, he took an infusion, pulse 78. There was no nausea ; after three-quarters of an hour, pulse 70, and a sensation of coldness; the pulse rose to 76. After four hours some colic and soft stool,'h