Croton Tiglium
Allen, Supplement to the Encyclopedia of Pure Materia Medica, 1879, Vol. X, p. 498
Authorities. 64, M. Andral, Gaz. Med. (Bost. Med. and Surg. Journ., vol. vi, 1832, p. 194), effect of application to the skin of from 4 to 20 drops in more than thirty cases; 65, Dr. Maudlin, Gaz. des Hop., 18()9, p. 290, a child, set. six years, took all at once 3 grams of Croton oil in a cup of coffee ; 66, G. H. Snead, M.D., Rich, and Louis. Med. Journ., 1872, p. 651, Mrs. S. took two teaspoonfuls of Croton oil mixed with two parts of sweet oil.
The child was taken with the most acute pain in the epigastric region, followed by violent, extremely profuse vomiting for three-quarters of an hour. After this she fell into a profound sleep for a quarter of an hour, when she called for food. She had no more pain in the epigastrium or abdomen, and had only two profuse stools. Afterwards there was a fine vesicular eruption on the lips caused by contact of the oil ; in other respects the child seemed well,®''.—Burning sensation in stomach and bowels; rapid and drastic purging (soon); pulse 150 and scarcely perceptible; entire surface bathed in cold, clammy sweat; countenance sunken; copious watery choleraic dejections every few minutes (after two hours),®®.—A few hours after the friction (supposing this to have been employed for some minutes) the patients experienced a smart tingling in the part. In some this sensation was transient; in others prolonged, but never to such an extent as to produce troublesome nervous disturbance ; at the same time there appeared a great number of little red points, at the apices of which there were soon perceptible little pustules which, within from thirty to fifty hours, had become fully developed. Many of these became united, and there formed large patches filled with white opaque fluid. The eruption increased for three or four days, after which it remained stationary, and subsequently died away like small-pox. In some cases where the oil was applied to the face the eruption was more copious and intense than elsewhere,®h