Atropinum

Clarke, A Dictionary of Practical Materia Medica, 1900, Vol. I, p. 217

Atropine. An alkaloid of Belladonna. Cx7 H NO3. The effects of the Sulphate of Atropine, the preparation most in use, are included. Solution.

Clinical

Blepharospasm. Convulsions. Enuresis. Epilepsy. Eyes, affections of. Gastric ulcer. Locomotor ataxy. Mania. Neuralgias. Pancreatitis Spinal urination. Stammering. Tetanus. Vision, disorders of. Wryneck*

Characteristics

Atropine, as the most active principle in Belladonna, produces, as we should expect, most of the characteristic effects of that drug; but at the same time the two are not identical Atrop. produces hyperaesthesia of the sensory nerves. The most numerous symptoms have been observed in the eyes. All kinds of illusions of vision. Everything appears large. Motes over everything. I once cured with it a lady who had an appearance of shadows passing over whatever she looked at It has shown an affinity for the pancreas, which relates it to lod. Kali iod,, and Iris, A case of chronic wryneck, of three years' standing, was relieved and finally cured within two weeks by injections of rv platysma, the dose being increased up to V- " was in old-school practice. It has caused difficulty of speech : frequent stuttering, especially at words difficult to pronounce ; articulation indistinct, rapid and chattering.

Relations p. 218

It antidotes : Muscarine and Opium. // is antidoted by : Op. and Physostigma. Like Bell., it is a right-side medicine.

Mind p. 218

Frenzied with excitement — Spectral illusions; sees insects and crawling things and tries to catch them. — Mania, tries to escape. — When spoken to often turns his head to wrong side.

Head p. 218

Vertigo on turning head suddenly. — Feeling as if head were screwed up ; walking caused the most severe sticking pains; > towards ii a.m., and disappeared by evening. — Head very hot. — Headaches of epileptics. — Sticking pains in back of skull and over eyes, < every motion and stepping. — Sticking l. temple on waking, extending into ear and eye ; > moving in open air. — Headache, with flushed face, blindness, and delirium.

Eyes p. 218

Objects appear large, with red halo. — Everything seems elongated, objects appear in a cloud.— Clouds of flies ; motes ; bright spots ; stars ; flashes. — Figures on carpet appear constantly and successively to rise in her face. — Diplopia.— Sharp neuralgic pains in and about eyes.— At 9 p.m. eyelids heavy, difficult to keep open.

Face p. 218

Face hot and very red. — Deathly pallor.

Mouth p. 218

Mouth dry. — Tongue thick ; cannot articulate distinctly. — Tongue semi-paralysed. — Speech slow, embarrassed, stuttering, chattering. Q. Throat. — Burning caused by coughing. — Dryness. — Dysphagia; swallowing causes paroxysms of suffocation. — Throat dark red.

Stomach p. 218

Vomiting of food ; after hot drinks ; with severe sticking pains in umbilical region. — > After vomiting. — Region of stomach very sensitive ; swelling in pyloric region.

Urinary Organs p. 218

Frequent micturition. — Involuntary, but scanty ; nocturnal enuresis. — Cutting, drawing pains in l. ovary, extorting screams, > bending; ovary swollen and tender during menses. — Epilepsy from ovarian irritation. IQ. Heart. — Failure of action from chloroform and other cardiac paralyzers. — Accelerated pulse.

Neck and Back p. 218

Burning in back under sternum and in region of stomach. — Spinal irritation, pressure causes pallor-, nausea, belching, and retching.

Limbs p. 218

Numbness ; heaviness ; paralysis of limbs.

Generalities p. 218

Hyperaesthesia of some nerves : ophthalmic, auditory, olfactory, vaginal, spinal, olar*plexus, nerves of uterus and bladder. — Great deare for open air (faintness). — Very weak in the open air. — Giddiness and staggering.— > From motion.

Sleep p. 219

Disturbed by gastric pains.— Restless through night— Waked by frightful dreams.

Atropinum in the other books