Yanadium
Clarke, A Dictionary of Practical Materia Medica, 1900, Vol. II, p. 1502
Vanadium. The Metal. V. (A.W. 51-2). Trituration. (Burnett used the '' soluble ammonium salf )
Clinical
Addison's disease. Atheroma. Fatty degeneration. Innutrition.
Characteristics
Burnett (Fifty Reasons) tells how he came to use Van. through reading the result of some experiments on animals in which the Salts of Vanadium produced * true cell destruction, the pigment escaping, the liver being hit hardest" Burnett had at the time a case of "fatty liver, atheroma of the arteries, much pain corresponding to the course of the basilar artery, -large, deeply pigmented patches on forehead, profound adynamia." Van. restored the patient, who was seventy, and at eighty he was "hale and hearty." Marc Jousset (L'Aii Mdd.f Ixxxix. 3i7) tells of experiments with salts of Van., chiefly the meta-vanadate of sodium, by Bonnet and others. Animals poisoned by intravenous injections rapidly develop Cheyne-Stokes respiration ; with little or no action on circulation or blood. These observers gave Vanadates to two hundred patients (suffering from tuberculosis, chlorosis, chronic rheumatism, neurasthenia, &c.), and produced in nearly all cases increased appetite, strength, and weight The amount of urea was also increased. They regard Van. as " an energetic excitant of nutrition," and probably an oxydat stimulating organic combustion. The dose was 2-5 mgr. in twenty-four hours, and only on three separate days in the week.
Relations
Coma<0 ; Fatty degeneration, Phos., Ars. Addison's disease, Adren. Tuberculosis, Tub., Bac.