Tohimbinum

Clarke, A Dictionary of Practical Materia Medica, 1900, Vol. II, p. 1578

Johimbm. A crystalline alkaloid obtained from the bark of the Ycimbdia, or Yumbehoa tree, of the Cameroons. N. O. Rubiaceae (?). C,3H3.N«04, or CttH3oN,04. Trituration.

Clinical

'Ditiresis* Heart, palpitation of. Impotence. Priapism. GhaMotofflttiM.— The natives of West Africa discovered a potent aphrodisiac in the bark of the Yohimbe tree and from this an active principle, Yohimbin has been isolated and tested in Europe (Therapist, December 15, 1900). It is a powerful stimulant of the genital function in males. In animals it causes increased liveliness and cheerfulness, hyperaemia of the conjunctiva, heat and redness of the ears, and of the nose also in dogs. Lambreghts (. Bclgc tPH viii. 188) relates the case of a young man, 28, '' thin, anaemic, nervous, and partially impotent/' who took a 5-mgr. tablet one morning, another in the evening, and a third the following morning. The symptoms of the Schema are his, and they were so severe that he discontinued the drug in spite of a certain amelioration of the sexual neurasthenia. Yohim. set up symptoms of fever, disordered the digestion, caused agitation and tremors, and increased the action of the heart. Eulenburg (DeuU Med. Woch. April 25, 1901, quoted B. M. y.) used Yohim. in lo-drop doses of a i per cent, solution, and in 5-m. tablets, "in cases of neurasthenic impotence with excellent results. Yohim. should be a homoeopathic remedy in priapism and congestive states of the sexual organs.

Relations

Coma : Erections, Pic. ac, Pho., Graph., Cantfa., Hdfb.

Mind

Intense agitation, with trembling;.

Face

Flying sensations of heat, heightening the colour.

Mouth

Tongue covered with a yellow ooat — Disagreeable metallic taste.

Stomach

Appetite almost completely disappeared.

Abdomen

Flying heats in abdomen.

Stool and Anus

Stools frequent, liquid, black, and bilious.

Urinary Organs

Urine clear, abundant, foamy, no trace of albumen ; had to rise three times in the night X5. Male Senal Organ&In the morning strong and lasting erections without increase of desire.*-Sexual neiira8liienia» with impotence, is relieved.— Enlargement of testicles and epididymis (animals). I9b HeartFlying sensation of heat in heart — Heart-beats more intense and more frequent ; poke, normally So, became io8.

Neck and Back p. 1579

Plying heat in back. at. Upper Limbs« — Hands trembled, he could scarcely write, and his writing was illegible.

Sleep p. 1579

No sleep all night.

Fever p. 1579

Three hours after the dose (5 mgr.), flying sensations of heat, true vapours (vapours) which heightened the complexion ; afterwards the same phenomena in the back, heart region, and lower abdomen, so that in spite of the cold weather the prover was inconvenienced by the inttaae heat and tendency to sweat.

Tohimbinum in the other books